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TY - JOUR AU - Burgoyne, Paul S. PY - 1982 DA - 1982/09/01 TI - Genetic homology and crossing over in the X and Y chromosomes of mammals JO - Human Genetics SP - 85 EP - 90 VL - 61 IS - 2 AB - The “X-Y crossover model” described in this paper postulates that (1) the pairing observed between the X and the Y chromosome at zygotene is a consequence of genetic homology, (2) there is a single obligatory crossover between the X and Y pairing segments, and (3) the segment of the X which pairs with the Y is protected from subsequent X inactivation. Genes distal to the proposed crossover (“pseudoautosomal genes”) will appear to be autosomally inherited because they will be transmitted to both male and female offspring. Some criteria for identifying pseudoautosomal genes are outlined. SN - 1432-1203 UR - https://doi.org/10.1007/BF00274192 DO - 10.1007/BF00274192 ID - Burgoyne1982 ER -