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TY - JOUR AU - Kelly, Leonard E. PY - 1983 DA - 1983/06/01 TI - An altered electroretinogram transient associated with an unusual jump response in a mutant ofDrosophila JO - Cellular and Molecular Neurobiology SP - 143 EP - 149 VL - 3 IS - 2 AB - 1.Mutations at thestoned locus ofDrosophila melanogaster produce a reversible temperature-sensitive debilitation. At permissive temperatures they also exhibit an unusual jump response to a light-off stimulus.2.An increase in the amplitude of the off-transient of the electroretinogram (ERG) is associated with this abnormal jump. Both the jump response and the increased amplitude of the off-transient are shown to be dependent on the duration of the light pulse prior to the light-off stimulus.3.Instoned flies which are light adapted, the jump response, as measured by recording from the indirect flight muscles, is seen to habituate with increasing light-off frequency. This habituation corresponds to the decrease in the amplitude of the off-transient that also occurs with high-frequency stimulation.4.Another visual mutanttan, removes the off and on-transients of the ERG.5.The combining of thestoned mutation withtan in thetan, stoned double mutant results in the loss of the jump behavior as well as the partial restoration of the off-transient to an otherwisetan-like ERG. The relationship between the increase in the amplitude of the off-transient instoned flies and the eliciting of the jump response is discussed. SN - 1573-6830 UR - https://doi.org/10.1007/BF00735278 DO - 10.1007/BF00735278 ID - Kelly1983 ER -