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TY - JOUR AU - Reynolds, D. J. AU - Debney, T. G. AU - Hall, G. A. AU - Thomas, L. H. AU - Parsons, K. R. PY - 1985 DA - 1985/03/01 TI - Studies on the relationship between coronaviruses from the intestinal and respiratory tracts of calves JO - Archives of Virology SP - 71 EP - 83 VL - 85 IS - 1 AB - An immunofluorescence test on smears of nasal epithelial cells was used to detect coronavirus infection in the respiratory tract of calves. Thirteen gnotobiotic calves were infected with coronavirus isolates derived from faeces or respiratory material: virus was detected in faeces and nasal swabs from all animals. In 115 calves from a field survey, there was a significant association between coronavirus excretion from both respiratory and enteric routes in calves with diarrhoea. In a further 12 calves, at necropsy, the predilection sites for coronavirus growth were the distal small intestine, large intestine and the epithelia of the nasal cavity and trachea. Antigen was not found in lung tissue by immunofluoresence or immunoperoxidase staining. SN - 1432-8798 UR - https://doi.org/10.1007/BF01317007 DO - 10.1007/BF01317007 ID - Reynolds1985 ER -