(original) (raw)

TY - JOUR AU - Haldane, J. B. S. PY - 1935 DA - 1935/10/01 TI - The rate of spontaneous mutation of a human gene JO - Journal of Genetics SP - 317 EP - 326 VL - 31 IS - 3 AB - The rate of mutation at which the gene for haemophilia appears in the population of London is estimated at about once in 50,000 human life cycles. There are probably two distinct allelomorphs at the same locus, the milder type arising less frequently by mutation than the severe type. SN - 0022-1333 UR - https://doi.org/10.1007/BF02982403 DO - 10.1007/BF02982403 ID - Haldane1935 ER -