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TY - JOUR AU - Larsen, S. AU - Rabøl, R. AU - Hansen, C. N. AU - Madsbad, S. AU - Helge, J. W. AU - Dela, F. PY - 2012 DA - 2012/02/01 TI - Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration JO - Diabetologia SP - 443 EP - 449 VL - 55 IS - 2 AB - The glucose-lowering drug metformin has been shown to inhibit complex I of the mitochondrial electron transport chain in skeletal muscle. To investigate this effect in vivo we studied skeletal muscle mitochondrial respiratory capacity and content from patients with type 2 diabetes treated with metformin (n = 14) or sulfonylurea (n = 8) and healthy control (n = 18) participants. SN - 1432-0428 UR - https://doi.org/10.1007/s00125-011-2340-0 DO - 10.1007/s00125-011-2340-0 ID - Larsen2012 ER -