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TY - JOUR AU - Yang, Zhikun AU - Li, Kanghua AU - Yan, Xi AU - Dong, Fangtian AU - Zhao, Chunhua PY - 2010 DA - 2010/10/01 TI - Amelioration of diabetic retinopathy by engrafted human adipose-derived mesenchymal stem cells in streptozotocin diabetic rats JO - Graefe's Archive for Clinical and Experimental Ophthalmology SP - 1415 EP - 1422 VL - 248 IS - 10 AB - Diabetic retinopathy is a common complication of diabetes, which is caused by injury to retinal microvasculature and neurons. Mesenchymal stem cells (MSCs), which proved to have multi-linkage differentiation capacity, including endothelial cells and neurons, might be a promising cell therapy resource. The current pilot study was performed using the streptozotocin (STZ) rat model of diabetic retinopathy injected intravenously with human adipose-derived mesenchymal stem cells (AMSCs) in an effort to investigate the potency and possible therapeutic effects of AMSCs. SN - 1435-702X UR - https://doi.org/10.1007/s00417-010-1384-z DO - 10.1007/s00417-010-1384-z ID - Yang2010 ER -