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TY - JOUR AU - Ito, Kei AU - Sass, Heinz AU - Urban, Joachim AU - Hofbauer, Alois AU - Schneuwly, Stephan PY - 1997 DA - 1997/09/01 TI - GAL4-responsive UAS-tau as a tool for studying the anatomy and development of the Drosophila central nervous system JO - Cell and Tissue Research SP - 1 EP - 10 VL - 290 IS - 1 AB - To improve the quality of cytoplasmic labelling of GAL4-expressing cells in Drosophila enhancer-trap and transgenic strains, a new GAL4-responsive reporter UAS-tau, which features a bovine tau cDNA under control of a yeast upstream activation sequence (UAS), was tested. Tau, a microtubule-associated protein, is distributed actively and evenly into all cellular processes. Monoclonal anti-bovine Tau antibody reveals the axonal structure of the labelled cells with detail similar to that of Golgi impregnation. We demonstrate that the UAS-tau system is especially useful for studying processes of differentiation and reorganisation of identified neurones during postembryonic development. SN - 1432-0878 UR - https://doi.org/10.1007/s004410050901 DO - 10.1007/s004410050901 ID - Ito1997 ER -