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TY - JOUR AU - Schlueter, M. AU - James, C. AU - Dominguez, A. AU - Tsu, L. AU - Seymann, G. PY - 2010 DA - 2010/10/01 TI - Practice patterns for antibiotic de-escalation in culture-negative healthcare-associated pneumonia JO - Infection SP - 357 EP - 362 VL - 38 IS - 5 AB - Published guidelines for the treatment of healthcare-associated pneumonia (HCAP) recommend initial broad-spectrum antibiotics with appropriate de-escalation based on culture results. Guideline recommendations are based on data from intubated patients, in whom cultures are easily obtained. The approach to antibiotic de-escalation for culture-negative patients has not been addressed. Consequently, there are no published reports that describe the current standard of practice. SN - 1439-0973 UR - https://doi.org/10.1007/s15010-010-0042-z DO - 10.1007/s15010-010-0042-z ID - Schlueter2010 ER -