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TY - JOUR AU - Capuron, Lucile AU - Gumnick, Jane F AU - Musselman, Dominique L AU - Lawson, David H AU - Reemsnyder, Andrea AU - Nemeroff, Charles B AU - Miller, Andrew H PY - 2002 DA - 2002/05/01 TI - Neurobehavioral Effects of Interferon-α in Cancer Patients: Phenomenology and Paroxetine Responsiveness of Symptom Dimensions JO - Neuropsychopharmacology SP - 643 EP - 652 VL - 26 IS - 5 AB - We have previously shown that the risk of major depression in patients with malignant melanoma undergoing interferon-α (IFN-α) therapy can be reduced by pretreatment with the antidepressant, paroxetine. Using dimensional analyses, the present study assessed the expression and treatment responsiveness of specific clusters of neuropsychiatric symptoms over the first three months of IFN-α therapy. SN - 1740-634X UR - https://doi.org/10.1016/S0893-133X(01)00407-9 DO - 10.1016/S0893-133X(01)00407-9 ID - Capuron2002 ER -