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TY - JOUR AU - McCammon, J. Andrew AU - Gelin, Bruce R. AU - Karplus, Martin PY - 1977 DA - 1977/06/01 TI - Dynamics of folded proteins JO - Nature SP - 585 EP - 590 VL - 267 IS - 5612 AB - The dynamics of a folded globular protein (bovine pancreatic trypsin inhibitor) have been studied by solving the equations of motion for the atoms with an empirical potential energy function. The results provide the magnitude, correlations and decay of fluctuations about the average structure. These suggest that the protein interior is fluid-like in that the local atom motions have a diffusional character. SN - 1476-4687 UR - https://doi.org/10.1038/267585a0 DO - 10.1038/267585a0 ID - McCammon1977 ER -