(original) (raw)

TY - JOUR AU - Hochschild, A. AU - Ptashne, M. PY - 1988 DA - 1988/11/01 TI - Interaction at a distance between λrepressers disrupts gene activation JO - Nature SP - 353 EP - 357 VL - 336 IS - 6197 AB - The λ represser is an activator as well as a represser of transcription. The activation function is blocked by interaction with another λrepresser molecule bound upstream on the same DNA molecule. This example of negative control at a distance involves formation of a DNA loop SN - 1476-4687 UR - https://doi.org/10.1038/336353a0 DO - 10.1038/336353a0 ID - Hochschild1988 ER -