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TY - JOUR AU - Lillie, James W. AU - Green, Michael R. PY - 1989 DA - 1989/03/01 TI - Transcription activation by the adenovirus E1a protein JO - Nature SP - 39 EP - 44 VL - 338 IS - 6210 AB - The adenovirus Ela protein stimulates transcription of a wide variety of viral and cellular genes. It is shown here that Ela has the two functions characteristic of a typical cellular activator: one direct Ela to the promoter, perhaps by interacting with a DMA-bound protein, and the other, an activating region, enables the bound activator to stimulate transcription. SN - 1476-4687 UR - https://doi.org/10.1038/338039a0 DO - 10.1038/338039a0 ID - Lillie1989 ER -