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TY - JOUR AU - Naylor, Gavin J. P. AU - Brown, Wesley M. PY - 1997 DA - 1997/08/01 TI - Structural biology and phylogenetic estimation JO - Nature SP - 527 EP - 528 VL - 388 IS - 6642 AB - When reconstructing evolutionary trees from DNA sequences, it is often assumed that increasing the amount of sequence will improve the phylogenetic estimate1,2. This is based on the notion that historical ‘signal’ will rise above misleading ‘noise’ as more sequence is gathered. Our analysis of mitochondrial genomes fails to support this assumption, but suggests a way to select objectively for data with maximum ‘signal-to-noise’ potential. SN - 1476-4687 UR - https://doi.org/10.1038/41460 DO - 10.1038/41460 ID - Naylor1997 ER -