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TY - JOUR AU - Powles, Thomas AU - Eder, Joseph Paul AU - Fine, Gregg D. AU - Braiteh, Fadi S. AU - Loriot, Yohann AU - Cruz, Cristina AU - Bellmunt, Joaquim AU - Burris, Howard A. AU - Petrylak, Daniel P. AU - Teng, Siew-leng AU - Shen, Xiaodong AU - Boyd, Zachary AU - Hegde, Priti S. AU - Chen, Daniel S. AU - Vogelzang, Nicholas J. PY - 2014 DA - 2014/11/01 TI - MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer JO - Nature SP - 558 EP - 562 VL - 515 IS - 7528 AB - The results of a clinical phase I study in metastatic urothelial bladder cancer treated with the MPDL3280A antibody show that expression of PD-L1 on tumour-infiltrating immune cells is relevant for the therapeutic response. SN - 1476-4687 UR - https://doi.org/10.1038/nature13904 DO - 10.1038/nature13904 ID - Powles2014 ER -