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TY - JOUR AU - Lefort, Nathalie AU - Feyeux, Maxime AU - Bas, Cécile AU - Féraud, Olivier AU - Bennaceur-Griscelli, Annelise AU - Tachdjian, Gerard AU - Peschanski, Marc AU - Perrier, Anselme L PY - 2008 DA - 2008/12/01 TI - Human embryonic stem cells reveal recurrent genomic instability at 20q11.21 JO - Nature Biotechnology SP - 1364 EP - 1366 VL - 26 IS - 12 AB - During long-term culture, human embryonic stem (hES) cells may acquire chromosomal abnormalities that compromise their potential clinical utility. Lefort et al. show that an amplification at 20q11.21 arose at relatively late passage number in three of five hES cell lines. SN - 1546-1696 UR - https://doi.org/10.1038/nbt.1509 DO - 10.1038/nbt.1509 ID - Lefort2008 ER -