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TY - JOUR AU - Puklowski, Anja AU - Homsi, Yahya AU - Keller, Debora AU - May, Martin AU - Chauhan, Sangeeta AU - Kossatz, Uta AU - Grünwald, Viktor AU - Kubicka, Stefan AU - Pich, Andreas AU - Manns, Michael P. AU - Hoffmann, Ingrid AU - Gönczy, Pierre AU - Malek, Nisar P. PY - 2011 DA - 2011/08/01 TI - The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication JO - Nature Cell Biology SP - 1004 EP - 1009 VL - 13 IS - 8 AB - The PLK4 kinase and centrosomal protein HsSAS-6 both regulate centrosome duplication. PLK4 negatively controls an FBXW5-containing ubiquitin ligase, which targets SAS-6 for destruction to restrict centrosome re-duplication. SN - 1476-4679 UR - https://doi.org/10.1038/ncb2282 DO - 10.1038/ncb2282 ID - Puklowski2011 ER -