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TY - JOUR AU - Samaha, Frederick F AU - McKenney, James AU - Bloedon, LeAnne T AU - Sasiela, William J AU - Rader, Daniel J PY - 2008 DA - 2008/08/01 TI - Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia JO - Nature Clinical Practice Cardiovascular Medicine SP - 497 EP - 505 VL - 5 IS - 8 AB - Many coronary heart disease patients fail to reach recommended LDL levels, either due to intolerance or inadequate response to available lipid-lowering therapy. Microsomal triglyceride transfer protein (MTP) inhibitors may provide a novel alternative pathway for LDL lowering. In this paper the authors tested the safety and LDL lowering efficacy of the MTP inhibitor, AEGR-733, alone and in combination with ezetimibe. SN - 1743-4300 UR - https://doi.org/10.1038/ncpcardio1250 DO - 10.1038/ncpcardio1250 ID - Samaha2008 ER -