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TY - JOUR AU - Do, Ron AU - Balick, Daniel AU - Li, Heng AU - Adzhubei, Ivan AU - Sunyaev, Shamil AU - Reich, David PY - 2015 DA - 2015/02/01 TI - No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans JO - Nature Genetics SP - 126 EP - 131 VL - 47 IS - 2 AB - David Reich, Shamil Sunyaev and colleagues report an analysis of the per-genome accumulation of nonsynonymous substitutions across diverse pairs of human populations. They find no evidence for a higher load of deleterious mutations in non-Africans than in West Africans and show that the observed patterns are not likely to reflect changes in natural selection. SN - 1546-1718 UR - https://doi.org/10.1038/ng.3186 DO - 10.1038/ng.3186 ID - Do2015 ER -