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TY - JOUR AU - Brett, David AU - Pospisil, Heike AU - Valcárcel, Juan AU - Reich, Jens AU - Bork, Peer PY - 2002 DA - 2002/01/01 TI - Alternative splicing and genome complexity JO - Nature Genetics SP - 29 EP - 30 VL - 30 IS - 1 AB - Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals. SN - 1546-1718 UR - https://doi.org/10.1038/ng803 DO - 10.1038/ng803 ID - Brett2002 ER -