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TY - JOUR AU - Song, Chun-Xiao AU - Clark, Tyson A AU - Lu, Xing-Yu AU - Kislyuk, Andrey AU - Dai, Qing AU - Turner, Stephen W AU - He, Chuan AU - Korlach, Jonas PY - 2012 DA - 2012/01/01 TI - Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine JO - Nature Methods SP - 75 EP - 77 VL - 9 IS - 1 AB - The DNA modification 5-hydroxymethylcytosine has recently been implicated in several biological processes. Enrichment by selective chemical labeling in combination with single-molecule, real-time sequencing provides sensitive detection of this epigenetic mark in genomic DNA at base-pair resolution. SN - 1548-7105 UR - https://doi.org/10.1038/nmeth.1779 DO - 10.1038/nmeth.1779 ID - Song2012 ER -