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TY - JOUR AU - Mameli, Manuel AU - Bellone, Camilla AU - Brown, Matthew T C AU - Lüscher, Christian PY - 2011 DA - 2011/04/01 TI - Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area JO - Nature Neuroscience SP - 414 EP - 416 VL - 14 IS - 4 AB - Cocaine is known to influence the synaptic plasticity of dopaminergic neurons in the ventral tegmental area (VTA). Contrary to the earlier studies, Mameli et al. find that cocaine treatment can reduce synaptic NMDA receptor currents while increasing the synaptic insertion of calcium-permeable AMPA receptors. Cocaine treatment also reversed the rule of spiking timing–dependent plasticity in the VTA. SN - 1546-1726 UR - https://doi.org/10.1038/nn.2763 DO - 10.1038/nn.2763 ID - Mameli2011 ER -