(original) (raw)

TY - JOUR AU - Likhtik, Ekaterina AU - Stujenske, Joseph M AU - A Topiwala, Mihir AU - Harris, Alexander Z AU - Gordon, Joshua A PY - 2014 DA - 2014/01/01 TI - Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety JO - Nature Neuroscience SP - 106 EP - 113 VL - 17 IS - 1 AB - This study examines neuronal activity coupling between the medial prefrontal cortex (mPFC), basolateral amygdala (BLA) and hippocampus during the recall phase of a differential fear conditioning task and during exposure to a novel open field. The authors show that theta frequency power and synchrony between the mPFC and BLA increase with successful discrimination of aversive versus safe cues, and that the mPFC activity leads that in the BLA during safety. SN - 1546-1726 UR - https://doi.org/10.1038/nn.3582 DO - 10.1038/nn.3582 ID - Likhtik2014 ER -