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TY - JOUR AU - Meng, Di AU - Sommella, Eduardo AU - Salviati, Emanuela AU - Campiglia, Pietro AU - Ganguli, Kriston AU - Djebali, Karim AU - Zhu, Weishu AU - Walker, W. Allan PY - 2020 DA - 2020/08/01 TI - Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine JO - Pediatric Research SP - 209 EP - 217 VL - 88 IS - 2 AB - Necrotizing enterocolitis (NEC), a necrotic inflammation of the intestine, represents a major health problem in the very premature infant. Although prevention is difficult, the combination of ingestion of maternal-expressed breastmilk in conjunction with a probiotic provides the best protection. In this study, we establish a mechanism for breastmilk/probiotic protection. SN - 1530-0447 UR - https://doi.org/10.1038/s41390-019-0740-x DO - 10.1038/s41390-019-0740-x ID - Meng2020 ER -