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TY - JOUR AU - Camacho, Christiam AU - Coulouris, George AU - Avagyan, Vahram AU - Ma, Ning AU - Papadopoulos, Jason AU - Bealer, Kevin AU - Madden, Thomas L. PY - 2009 DA - 2009/12/15 TI - BLAST+: architecture and applications JO - BMC Bioinformatics SP - 421 VL - 10 IS - 1 AB - Sequence similarity searching is a very important bioinformatics task. While Basic Local Alignment Search Tool (BLAST) outperforms exact methods through its use of heuristics, the speed of the current BLAST software is suboptimal for very long queries or database sequences. There are also some shortcomings in the user-interface of the current command-line applications. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-10-421 DO - 10.1186/1471-2105-10-421 ID - Camacho2009 ER -