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TY - JOUR AU - Reed, Danielle R. AU - Lawler, Maureen P. AU - Tordoff, Michael G. PY - 2008 DA - 2008/01/08 TI - Reduced body weight is a common effect of gene knockout in mice JO - BMC Genetics SP - 4 VL - 9 IS - 1 AB - During a search for obesity candidate genes in a small region of the mouse genome, we noticed that many genes when knocked out influence body weight. To determine whether this was a general feature of gene knockout or a chance occurrence, we surveyed the Jackson Laboratory Mouse Genome Database for knockout mouse strains and their phenotypes. Body weights were not available for all strains so we also obtained body weight information by contacting a random sample of investigators responsible for a knockout strain. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-9-4 DO - 10.1186/1471-2156-9-4 ID - Reed2008 ER -