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TY - JOUR AU - Ranganathan, Prathibha AU - Agrawal, Animesh AU - Bhushan, Raghu AU - Chavalmane, Aravinda K. AU - Kalathur, Ravi Kiran Reddy AU - Takahashi, Takashi AU - Kondaiah, Paturu PY - 2007 DA - 2007/04/11 TI - Expression profiling of genes regulated by TGF-beta: Differential regulation in normal and tumour cells JO - BMC Genomics SP - 98 VL - 8 IS - 1 AB - TGF-beta is one of the key cytokines implicated in various disease processes including cancer. TGF-beta inhibits growth and promotes apoptosis in normal epithelial cells and in contrast, acts as a pro-tumour cytokine by promoting tumour angiogenesis, immune-escape and metastasis. It is not clear if various actions of TGF-beta on normal and tumour cells are due to differential gene regulations. Hence we studied the regulation of gene expression by TGF-beta in normal and cancer cells. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-8-98 DO - 10.1186/1471-2164-8-98 ID - Ranganathan2007 ER -