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TY - JOUR AU - Reyes-Zurita, Fernando J. AU - Pachón-Peña, Gisela AU - Lizárraga, Daneida AU - Rufino-Palomares, Eva E. AU - Cascante, Marta AU - Lupiáñez, José A. PY - 2011 DA - 2011/04/27 TI - The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism JO - BMC Cancer SP - 154 VL - 11 IS - 1 AB - Maslinic acid, a pentacyclic triterpene found in the protective wax-like coating of the leaves and fruit of Olea europaea L., is a promising agent for the prevention of colon cancer. We have shown elsewhere that maslinic acid inhibits cell proliferation to a significant extent and activates mitochondrial apoptosis in colon cancer cells. In our latest work we have investigated further this compound's apoptotic molecular mechanism. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-11-154 DO - 10.1186/1471-2407-11-154 ID - Reyes-Zurita2011 ER -