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TY - JOUR AU - Goh, Jorming AU - Enns, Linda AU - Fatemie, Soroosh AU - Hopkins, Heather AU - Morton, John AU - Pettan-Brewer, Christina AU - Ladiges, Warren PY - 2011 DA - 2011/05/23 TI - Mitochondrial targeted catalase suppresses invasive breast cancer in mice JO - BMC Cancer SP - 191 VL - 11 IS - 1 AB - Treatment of invasive breast cancer has an alarmingly high rate of failure because effective targets have not been identified. One potential target is mitochondrial generated reactive oxygen species (ROS) because ROS production has been associated with changes in substrate metabolism and lower concentration of anti-oxidant enzymes in tumor and stromal cells and increased metastatic potential. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-11-191 DO - 10.1186/1471-2407-11-191 ID - Goh2011 ER -