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TY - JOUR AU - Wolozin, Benjamin AU - Wang, Stanley W. AU - Li, Nien-Chen AU - Lee, Austin AU - Lee, Todd A. AU - Kazis, Lewis E. PY - 2007 DA - 2007/07/19 TI - Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease JO - BMC Medicine SP - 20 VL - 5 IS - 1 AB - Statins are a class of medications that reduce cholesterol by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Whether statins can benefit patients with dementia remains unclear because of conflicting results. We hypothesized that some of the confusion in the literature might arise from differences in efficacy of different statins. We used a large database to compare the action of several different statins to investigate whether some statins might be differentially associated with a reduction in the incidence of dementia and Parkinson's disease. SN - 1741-7015 UR - https://doi.org/10.1186/1741-7015-5-20 DO - 10.1186/1741-7015-5-20 ID - Wolozin2007 ER -