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TY - JOUR AU - Pyrc, Krzysztof AU - Jebbink, Maarten F. AU - Berkhout, Ben AU - van der Hoek, Lia PY - 2004 DA - 2004/11/17 TI - Genome structure and transcriptional regulation of human coronavirus NL63 JO - Virology Journal SP - 7 VL - 1 IS - 1 AB - Two human coronaviruses are known since the 1960s: HCoV-229E and HCoV-OC43. SARS-CoV was discovered in the early spring of 2003, followed by the identification of HCoV-NL63, the fourth member of the coronaviridae family that infects humans. In this study, we describe the genome structure and the transcription strategy of HCoV-NL63 by experimental analysis of the viral subgenomic mRNAs. SN - 1743-422X UR - https://doi.org/10.1186/1743-422X-1-7 DO - 10.1186/1743-422X-1-7 ID - Pyrc2004 ER -