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TY - JOUR AU - Mani, Venkatesh AU - Hollis, James H. AU - Gabler, Nicholas K. PY - 2013 DA - 2013/01/10 TI - Dietary oil composition differentially modulates intestinal endotoxin transport and postprandial endotoxemia JO - Nutrition & Metabolism SP - 6 VL - 10 IS - 1 AB - Intestinal derived endotoxin and the subsequent endotoxemia can be considered major predisposing factors for diseases such as atherosclerosis, sepsis, obesity and diabetes. Dietary fat has been shown to increase postprandial endotoxemia. Therefore, the aim of this study was to assess the effects of different dietary oils on intestinal endotoxin transport and postprandial endotoxemia using swine as a model. We hypothesized that oils rich in saturated fatty acids (SFA) would augment, while oils rich in n-3 polyunsaturated fatty acids (PUFA) would attenuate intestinal endotoxin transport and circulating concentrations. SN - 1743-7075 UR - https://doi.org/10.1186/1743-7075-10-6 DO - 10.1186/1743-7075-10-6 ID - Mani2013 ER -