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TY - JOUR AU - Liu, Qiang AU - Zhang, Juan AU - Tran, Hien AU - Verbeek, Marcel M. AU - Reiss, Karina AU - Estus, Steven AU - Bu, Guojun PY - 2009 DA - 2009/04/16 TI - LRP1 shedding in human brain: roles of ADAM10 and ADAM17 JO - Molecular Neurodegeneration SP - 17 VL - 4 IS - 1 AB - The low-density lipoprotein receptor-related protein 1 (LRP1) plays critical roles in lipid metabolism, cell survival, and the clearance of amyloid-β (Aβ) peptide. Functional soluble LRP1 (sLRP1) has been detected in circulating human placenta; however, whether sLRP1 is also present in the central nervous system is unclear. SN - 1750-1326 UR - https://doi.org/10.1186/1750-1326-4-17 DO - 10.1186/1750-1326-4-17 ID - Liu2009 ER -