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TY - JOUR AU - Baumler, David J. AU - Ma, Bing AU - Reed, Jennifer L. AU - Perna, Nicole T. PY - 2013 DA - 2013/06/11 TI - Inferring ancient metabolism using ancestral core metabolic models of enterobacteria JO - BMC Systems Biology SP - 46 VL - 7 IS - 1 AB - Enterobacteriaceae diversified from an ancestral lineage ~300-500 million years ago (mya) into a wide variety of free-living and host-associated lifestyles. Nutrient availability varies across niches, and evolution of metabolic networks likely played a key role in adaptation. SN - 1752-0509 UR - https://doi.org/10.1186/1752-0509-7-46 DO - 10.1186/1752-0509-7-46 ID - Baumler2013 ER -