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TY - JOUR AU - Young, Robert S. AU - Kumar, Yatendra AU - Bickmore, Wendy A. AU - Taylor, Martin S. PY - 2017 DA - 2017/12/28 TI - Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers JO - Genome Biology SP - 242 VL - 18 IS - 1 AB - Enhancers are modular regulatory elements that are central to the spatial and temporal regulation of gene expression. Bidirectional transcription initiating at enhancers has been proposed to mark active enhancers and as such has been utilized to experimentally identify active enhancers de novo. SN - 1474-760X UR - https://doi.org/10.1186/s13059-017-1379-8 DO - 10.1186/s13059-017-1379-8 ID - Young2017 ER -