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TY - JOUR AU - Zhang, Chuanjian AU - Peng, Yu AU - Mu, Chunlong AU - Zhu, Weiyun PY - 2018 DA - 2018/07/02 TI - Ileum terminal antibiotic infusion affects jejunal and colonic specific microbial population and immune status in growing pigs JO - Journal of Animal Science and Biotechnology SP - 51 VL - 9 IS - 1 AB - Compared with oral antibiotics (primarily disrupt foregut microbiota), the present study used antibiotics with ileum terminal infusion to disrupt the hindgut microbiota, and investigated the changes in specific bacterial composition and immune indexes in the jejunum and colon, and serum of growing pigs. Twelve barrows (45 d of age, 12.08 ± 0.28 kg) fitted with a T-cannula at the terminal ileum, were randomly assigned to two groups and infused either saline without antibiotics (Control) or with antibiotics (Antibiotic) at the terminal ileum. After 25 d experiment, all pigs were euthanized for analyzing bacterial composition and immune status. SN - 2049-1891 UR - https://doi.org/10.1186/s40104-018-0265-x DO - 10.1186/s40104-018-0265-x ID - Zhang2018 ER -