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TY - JOUR AU - Cuello-Garcia, Carlos A. AU - Fiocchi, Alessandro AU - Pawankar, Ruby AU - Yepes-Nuñez, Juan José AU - Morgano, Gian Paolo AU - Zhang, Yuan AU - Ahn, Kangmo AU - Al-Hammadi, Suleiman AU - Agarwal, Arnav AU - Gandhi, Shreyas AU - Beyer, Kirsten AU - Burks, Wesley AU - Canonica, Giorgio W. AU - Ebisawa, Motohiro AU - Kamenwa, Rose AU - Lee, Bee Wah AU - Li, Haiqi AU - Prescott, Susan AU - Riva, John J. AU - Rosenwasser, Lanny AU - Sampson, Hugh AU - Spigler, Michael AU - Terracciano, Luigi AU - Vereda, Andrea AU - Waserman, Susan AU - Schünemann, Holger J. AU - Brożek, Jan L. PY - 2016 DA - 2016/03/01 TI - World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics JO - World Allergy Organization Journal SP - 10 VL - 9 IS - 1 AB - The prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10 % and reaches 20–30 % in those with an allergic first-degree relative. Intestinal microbiota may modulate immunologic and inflammatory systemic responses and, thus, influence development of sensitization and allergy. Prebiotics – non-digestible oligosaccharides that stimulate growth of probiotic bacteria – have been reported to modulate immune responses and their supplementation has been proposed as a preventive intervention. SN - 1939-4551 UR - https://doi.org/10.1186/s40413-016-0102-7 DO - 10.1186/s40413-016-0102-7 ID - Cuello-Garcia2016 ER -