Jennifer A Lyon | The Children's Mercy Hospital (original) (raw)

Papers by Jennifer A Lyon

Research paper thumbnail of A model for training the new bioinformationist

Journal of the Medical Library Association Jmla, Apr 1, 2004

Objectives: The objectives were to examine the effectiveness of a curriculum designed to increase... more Objectives: The objectives were to examine the effectiveness of a curriculum designed to increase bioinformatics competencies of librarians with diverse backgrounds and to identify demographic factors that may affect the learning process.Methods: Sixteen professional staff participated in a 12-week training course consisting of 5 distinct modules: molecular biology, genetic analysis, biotechnology, research literature, and databases. Participants completed a 120-question pretest and an 88-question posttest designed to evaluate the effectiveness of the training.Results: Training was deemed successful as all participants scored higher on the posttest than the pretest. Data analysis was conducted in relation to participant background. Holding a biology degree did not seem to affect posttest results. Years of experience, however, had an impact on final scores in the databases section, as senior team members had greater difficulty learning the material.Discussion: As the need for specialized information in the area of molecular biology and genetics becomes more central for the effectiveness of organizations, it is crucial for libraries to quickly align with those needs by having a clear vision for increasing the skills and competencies of their staff in this subject area. This paper describes an effective model for learning that was developed and tested by the Eskind Biomedical Library.

Research paper thumbnail of Carving a niche: establishing bioinformatics collaborations

Journal of the Medical Library Association Jmla, Jul 1, 2006

Objectives: The paper describes collaborations and partnerships developed between library bioinfo... more Objectives: The paper describes collaborations and partnerships developed between library bioinformatics programs and other bioinformatics-related units at four academic institutions.Methods: A call for information on bioinformatics partnerships was made via email to librarians who have participated in the National Center for Biotechnology Information's Advanced Workshop for Bioinformatics Information Specialists. Librarians from Harvard University, the University of Florida, the University of Minnesota, and Vanderbilt University responded and expressed willingness to contribute information on their institutions, programs, services, and collaborating partners. Similarities and differences in programs and collaborations were identified.Results: The four librarians have developed partnerships with other units on their campuses that can be categorized into the following areas: knowledge management, instruction, and electronic resource support. All primarily support freely accessible electronic resources, while other campus units deal with fee-based ones. These demarcations are apparent in resource provision as well as in subsequent support and instruction.Conclusions and Recommendations: Through environmental scanning and networking with colleagues, librarians who provide bioinformatics support can develop fruitful collaborations. Visibility is key to building collaborations, as is broad-based thinking in terms of potential partners.

Research paper thumbnail of Carving a niche: establishing bioinformatics collaborations

Journal of the Medical Library Association : JMLA, 2006

The paper describes collaborations and partnerships developed between library bioinformatics prog... more The paper describes collaborations and partnerships developed between library bioinformatics programs and other bioinformatics-related units at four academic institutions. A call for information on bioinformatics partnerships was made via email to librarians who have participated in the National Center for Biotechnology Information's Advanced Workshop for Bioinformatics Information Specialists. Librarians from Harvard University, the University of Florida, the University of Minnesota, and Vanderbilt University responded and expressed willingness to contribute information on their institutions, programs, services, and collaborating partners. Similarities and differences in programs and collaborations were identified. The four librarians have developed partnerships with other units on their campuses that can be categorized into the following areas: knowledge management, instruction, and electronic resource support. All primarily support freely accessible electronic resources, whil...

Research paper thumbnail of A model for training the new bioinformationist

Journal of the Medical Library Association : JMLA, 2004

The objectives were to examine the effectiveness of a curriculum designed to increase bioinformat... more The objectives were to examine the effectiveness of a curriculum designed to increase bioinformatics competencies of librarians with diverse backgrounds and to identify demographic factors that may affect the learning process. Sixteen professional staff participated in a 12-week training course consisting of 5 distinct modules: molecular biology, genetic analysis, biotechnology, research literature, and databases. Participants completed a 120-question pretest and an 88-question posttest designed to evaluate the effectiveness of the training. Training was deemed successful as all participants scored higher on the posttest than the pretest. Data analysis was conducted in relation to participant background. Holding a biology degree did not seem to affect posttest results. Years of experience, however, had an impact on final scores in the databases section, as senior team members had greater difficulty learning the material. As the need for specialized information in the area of molecul...

Research paper thumbnail of Library-based clinical and translational research support

Journal of the Medical Library Association, 2013

Research paper thumbnail of Beyond the Literature

Medical Reference Services Quarterly, 2003

As genetics and molecular biology progressively impact on society and the practice of medicine, m... more As genetics and molecular biology progressively impact on society and the practice of medicine, medical librarians must prepare themselves to deal with this new arena of information. The Eskind Biomedical Library at Vanderbilt University Medical Center has developed a bioinformatics training program for its librarians involving subject knowledge, literature evaluation, and database searching techniques. This program can serve as a model for other libraries.

Research paper thumbnail of Entrez Gene

Journal of Electronic Resources in Medical Libraries, 2007

... 32610-0206. Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Researc... more ... 32610-0206. Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Research Informatics Con-sult Service, Eskind Biomedical Library, Vanderbilt University Medical Center, Nash-ville, TN 37232-8340. The ...

Research paper thumbnail of Is video review of patient encounters an effective tool for medical student learning? A review of the literature

Advances in Medical Education and Practice, 2012

To determine if video review of student performance during patient encounters is an effective too... more To determine if video review of student performance during patient encounters is an effective tool for medical student learning. Methods: Multiple bibliographic databases that include medical, general health care, education, psychology, and behavioral science literature were searched for the following terms: medical students, medical education, undergraduate medical education, education, self-assessment, self-evaluation, self-appraisal, feedback, videotape, video recording, televised, and DVD. The authors examined all abstracts resulting from this search and reviewed the full text of the relevant articles as well as additional articles identified in the reference lists of the relevant articles. Studies were classified by year of student (preclinical or clinical) and study design (controlled or non-controlled). Results: A total of 67 articles met the final search criteria and were fully reviewed. Most studies were non-controlled and performed in the clinical years. Although the studies were quite variable in quality, design, and outcomes, in general video recording of performance and subsequent review by students with expert feedback had positive outcomes in improving feedback and ultimate performance. Video review with self-assessment alone was not found to be generally effective, but when linked with expert feedback it was superior to traditional feedback alone. Conclusion: There are many methods for integrating effective use of video-captured performance into a program of learning. We recommend combining student self-assessment with feedback from faculty or other trained individuals for maximum effectiveness. We also recommend additional research in this area. Keywords: feedback tools, self-assessment of performance, self-directed learning with feedback, feedback and self-assessment, video review of performance with feedback Dovepress submit your manuscript | www.dovepress.com

Research paper thumbnail of The Lived Experience and Training Needs of Librarians Serving at the Clinical Point-of-Care

Medical reference services quarterly, 2015

This study examines the emotional experiences and perceptions of librarians embedded into clinica... more This study examines the emotional experiences and perceptions of librarians embedded into clinical care teams and how those perceptions affect their training and preparation needs. Qualitative research methodologies were applied to textual data drawn from focus groups (n = 21), interviews (n = 2), and an online survey (n = 167), supplemented by quantitative survey data. Phenomenological results show librarians experience strongly affective responses to clinical rounding. Important factors include personal confidence; relationships with team members, patients, and families; and the stressful environment. Analysis of librarians' perceived educational needs indicates that training must address specialized subjects including medical knowledge, clinical culture, and institutional politics.

Research paper thumbnail of Hepatotoxicity from antituberculous therapy in the elderly: A systematic review

Tuberculosis (Edinburgh, Scotland), Jan 18, 2014

Elderly persons have the highest rates of tuberculosis (TB) in the United States compared to all ... more Elderly persons have the highest rates of tuberculosis (TB) in the United States compared to all other age groups. A systematic literature review was conducted to determine if older age was a risk factor for hepatotoxicity resulting from treatment with first-line drugs used to treat active (TB) and latent tuberculosis (LTBI). A systematic review of MEDLINE, Cochrane Controlled Trial Registry, CINAHL(®), and Science Citation Index Expanded (from 1970 to 2011) was performed to determine the risk of hepatotoxicity, comparing those over 60 with those under 60. A meta-analysis was performed using a random effects model along with log odds ratios and the chi-square test. Thirty-eight studies (40,034 participants; 1208 cases of hepatotoxicity) met the selection criteria. For active TB, an overall mean effect of 0.277 (p = 0.024, 95% CI: 0.037-0.517) was observed, which is equivalent to an odds ratio of 1.32 (95% CI: 1.04-1.68). For LTBI, an overall mean effect of 1.42 (p < 0.001, 95% CI...

Research paper thumbnail of A systematic review of emergency department point-of-care cardiac markers and efficiency measures

Point of Care, 2009

Advertisement. Close Window. Close Window. Thank you for choosing to subscribe to the eTOC for Po... more Advertisement. Close Window. Close Window. Thank you for choosing to subscribe to the eTOC for Point of Care. Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed ...

Research paper thumbnail of The Use of Research Electronic Data Capture (REDCap) Software to Create a Database of Librarian-Mediated Literature Searches

Medical Reference Services Quarterly, 2014

Expert-mediated literature searching, a keystone service in biomedical librarianship, would benef... more Expert-mediated literature searching, a keystone service in biomedical librarianship, would benefit significantly from regular methodical review. This article describes the novel use of Research Electronic Data Capture (REDCap) software to create a database of literature searches conducted at a large academic health sciences library. An archive of paper search requests was entered into REDCap, and librarians now prospectively enter records for current searches. Having search data readily available allows librarians to reuse search strategies and track their workload. In aggregate, this data can help guide practice and determine priorities by identifying users&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; needs, tracking librarian effort, and focusing librarians&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; continuing education.

Research paper thumbnail of Assessing learners’ needs

Oxford Textbook of Medical Education, 2013

Research paper thumbnail of Changing the Face of Reference: Adapting Biomedical and Health Information Services for the Classroom, Clinic, and Beyond

Medical Reference Services Quarterly, 2012

This paper describes how the reference department at a large academic health sciences library evo... more This paper describes how the reference department at a large academic health sciences library evolved to address the clinical and research information needs of the parent organization without losing its close connections to the classroom and curriculum. Closing the reference desk, moving to on-call and house call models, designing positions such as clinical research librarian and basic biomedical sciences librarian, finding alternative funding to grow the department, providing technology and training to facilitate librarians' work, and developing programming for and taking advice from library clients facilitated efforts to create a relevant presence and solidify the library's place in the university community.

Research paper thumbnail of Using the literature to evaluate diagnostic tests: amylase or lipase for diagnosing acute pancreatitis?

Journal of the Medical Library Association, 2007

Research paper thumbnail of Replication of Influenza A Viruses in an Avian Macrophage Cell Line

Journal of General Virology, 1991

Research paper thumbnail of Introducing Protein Data Bank, Molecular Modeling Database, and Cn3D

Journal of Electronic Resources in Medical Libraries, 2006

... viewers Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Re-search I... more ... viewers Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Re-search Informatics Consult Service, Eskind Biomedical Library, Vanderbilt University Medical Center, Nashville, TN 37232-8340. Michele ...

Research paper thumbnail of Management of penetrating neck injury in the emergency department: a structured literature review

Emergency Medicine Journal, 2008

The management of patients with penetrating neck injuries in the prehospital setting and in the e... more The management of patients with penetrating neck injuries in the prehospital setting and in the emergency department has evolved with regard to the necessity for spinal immobilisation and the use of multidetector computed tomographic (MDCT) imaging. Questions also arise as to choices of securing a threatened or compromised airway. A structured review of the medical literature was conducted to provide current recommendations for the management of patients with penetrating neck injury. Databases for PubMed, MEDLINE, CINAHL and Cochrane EBM Reviews were electronically searched using the subject headings &quot;penetrating neck injury&quot;, &quot;penetrating neck trauma&quot;, &quot;cervical immobilization&quot;, &quot;multi-detector CTA&quot; and &quot;airway management&quot;. The results generated by the search were limited to English language articles and reviewed for relevance to the topic. 122 citations were identified that met the criteria for emphasis on emergency department care, cervical spine immobilisation, use of multidetector CT angiography or airway management. After excluding case series, non-peer reviewed articles and editorials, 20 articles were identified and reviewed. The current literature suggests that prehospital cervical immobilisation may not be necessary unless the patient has focal neurological deficits. Studies show that patients with penetrating neck trauma who are haemodynamically stable and exhibit no &quot;hard signs&quot; of vascular injury may be evaluated initially by MDCT imaging even when platysma violation is present. Airway management is evolving, but traditional laryngoscopy continues to be the mainstay of airway stabilisation.

Research paper thumbnail of Inhibition of Nitric Oxide Induction from Avian Macrophage Cell Lines by Influenza Virus

Avian Diseases, 1993

The virulent avian influenza virus A/Ty/Ont/7732/66 (H5N9) (Ty/Ont) causes a rapid destruction of... more The virulent avian influenza virus A/Ty/Ont/7732/66 (H5N9) (Ty/Ont) causes a rapid destruction of lymphoid cells in infected birds. Avian macrophage cell lines, HD11 and MQ-NCSU, support productive replication of Ty/Ont and other influenza viruses. Therefore, the ability of these cell lines to produce nitric oxide (NO), a potentially cytotoxic mediator, in response to infection with Ty/Ont was examined. Although treatment with bacterial lipopolysaccharides (LPS) resulted in high NO levels, infection of macrophages with Ty/Ont resulted in NO levels lower than NO levels in untreated cells. Furthermore, Ty/Ont was able to inhibit the positive response to LPS in cultures simultaneously treated with LPS and virus. However, inactivated influenza virus did not exhibit this inhibitory effect. Different strains of influenza virus varied in their ability to inhibit NO production by the macrophages; this may be related to the level of virus replication in these cells. These data suggest that the ability of the avian macrophage to activate the NO synthesis pathway is seriously impaired by infection with virulent influenza viruses such as Ty/Ont.

Research paper thumbnail of Agreement of Decision Analyses and Subsequent Clinical Studies in Infectious Diseases

The American Journal of Medicine, 2007

Purpose: Decision analysis techniques can compare management strategies when there are insufficie... more Purpose: Decision analysis techniques can compare management strategies when there are insufficient data from clinical studies to guide decision-making. We compared the outcomes of decision analyses and subsequent clinical studies in the infectious disease literature to assess the validity of the conclusions of the decision analyses.

Research paper thumbnail of A model for training the new bioinformationist

Journal of the Medical Library Association Jmla, Apr 1, 2004

Objectives: The objectives were to examine the effectiveness of a curriculum designed to increase... more Objectives: The objectives were to examine the effectiveness of a curriculum designed to increase bioinformatics competencies of librarians with diverse backgrounds and to identify demographic factors that may affect the learning process.Methods: Sixteen professional staff participated in a 12-week training course consisting of 5 distinct modules: molecular biology, genetic analysis, biotechnology, research literature, and databases. Participants completed a 120-question pretest and an 88-question posttest designed to evaluate the effectiveness of the training.Results: Training was deemed successful as all participants scored higher on the posttest than the pretest. Data analysis was conducted in relation to participant background. Holding a biology degree did not seem to affect posttest results. Years of experience, however, had an impact on final scores in the databases section, as senior team members had greater difficulty learning the material.Discussion: As the need for specialized information in the area of molecular biology and genetics becomes more central for the effectiveness of organizations, it is crucial for libraries to quickly align with those needs by having a clear vision for increasing the skills and competencies of their staff in this subject area. This paper describes an effective model for learning that was developed and tested by the Eskind Biomedical Library.

Research paper thumbnail of Carving a niche: establishing bioinformatics collaborations

Journal of the Medical Library Association Jmla, Jul 1, 2006

Objectives: The paper describes collaborations and partnerships developed between library bioinfo... more Objectives: The paper describes collaborations and partnerships developed between library bioinformatics programs and other bioinformatics-related units at four academic institutions.Methods: A call for information on bioinformatics partnerships was made via email to librarians who have participated in the National Center for Biotechnology Information's Advanced Workshop for Bioinformatics Information Specialists. Librarians from Harvard University, the University of Florida, the University of Minnesota, and Vanderbilt University responded and expressed willingness to contribute information on their institutions, programs, services, and collaborating partners. Similarities and differences in programs and collaborations were identified.Results: The four librarians have developed partnerships with other units on their campuses that can be categorized into the following areas: knowledge management, instruction, and electronic resource support. All primarily support freely accessible electronic resources, while other campus units deal with fee-based ones. These demarcations are apparent in resource provision as well as in subsequent support and instruction.Conclusions and Recommendations: Through environmental scanning and networking with colleagues, librarians who provide bioinformatics support can develop fruitful collaborations. Visibility is key to building collaborations, as is broad-based thinking in terms of potential partners.

Research paper thumbnail of Carving a niche: establishing bioinformatics collaborations

Journal of the Medical Library Association : JMLA, 2006

The paper describes collaborations and partnerships developed between library bioinformatics prog... more The paper describes collaborations and partnerships developed between library bioinformatics programs and other bioinformatics-related units at four academic institutions. A call for information on bioinformatics partnerships was made via email to librarians who have participated in the National Center for Biotechnology Information's Advanced Workshop for Bioinformatics Information Specialists. Librarians from Harvard University, the University of Florida, the University of Minnesota, and Vanderbilt University responded and expressed willingness to contribute information on their institutions, programs, services, and collaborating partners. Similarities and differences in programs and collaborations were identified. The four librarians have developed partnerships with other units on their campuses that can be categorized into the following areas: knowledge management, instruction, and electronic resource support. All primarily support freely accessible electronic resources, whil...

Research paper thumbnail of A model for training the new bioinformationist

Journal of the Medical Library Association : JMLA, 2004

The objectives were to examine the effectiveness of a curriculum designed to increase bioinformat... more The objectives were to examine the effectiveness of a curriculum designed to increase bioinformatics competencies of librarians with diverse backgrounds and to identify demographic factors that may affect the learning process. Sixteen professional staff participated in a 12-week training course consisting of 5 distinct modules: molecular biology, genetic analysis, biotechnology, research literature, and databases. Participants completed a 120-question pretest and an 88-question posttest designed to evaluate the effectiveness of the training. Training was deemed successful as all participants scored higher on the posttest than the pretest. Data analysis was conducted in relation to participant background. Holding a biology degree did not seem to affect posttest results. Years of experience, however, had an impact on final scores in the databases section, as senior team members had greater difficulty learning the material. As the need for specialized information in the area of molecul...

Research paper thumbnail of Library-based clinical and translational research support

Journal of the Medical Library Association, 2013

Research paper thumbnail of Beyond the Literature

Medical Reference Services Quarterly, 2003

As genetics and molecular biology progressively impact on society and the practice of medicine, m... more As genetics and molecular biology progressively impact on society and the practice of medicine, medical librarians must prepare themselves to deal with this new arena of information. The Eskind Biomedical Library at Vanderbilt University Medical Center has developed a bioinformatics training program for its librarians involving subject knowledge, literature evaluation, and database searching techniques. This program can serve as a model for other libraries.

Research paper thumbnail of Entrez Gene

Journal of Electronic Resources in Medical Libraries, 2007

... 32610-0206. Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Researc... more ... 32610-0206. Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Research Informatics Con-sult Service, Eskind Biomedical Library, Vanderbilt University Medical Center, Nash-ville, TN 37232-8340. The ...

Research paper thumbnail of Is video review of patient encounters an effective tool for medical student learning? A review of the literature

Advances in Medical Education and Practice, 2012

To determine if video review of student performance during patient encounters is an effective too... more To determine if video review of student performance during patient encounters is an effective tool for medical student learning. Methods: Multiple bibliographic databases that include medical, general health care, education, psychology, and behavioral science literature were searched for the following terms: medical students, medical education, undergraduate medical education, education, self-assessment, self-evaluation, self-appraisal, feedback, videotape, video recording, televised, and DVD. The authors examined all abstracts resulting from this search and reviewed the full text of the relevant articles as well as additional articles identified in the reference lists of the relevant articles. Studies were classified by year of student (preclinical or clinical) and study design (controlled or non-controlled). Results: A total of 67 articles met the final search criteria and were fully reviewed. Most studies were non-controlled and performed in the clinical years. Although the studies were quite variable in quality, design, and outcomes, in general video recording of performance and subsequent review by students with expert feedback had positive outcomes in improving feedback and ultimate performance. Video review with self-assessment alone was not found to be generally effective, but when linked with expert feedback it was superior to traditional feedback alone. Conclusion: There are many methods for integrating effective use of video-captured performance into a program of learning. We recommend combining student self-assessment with feedback from faculty or other trained individuals for maximum effectiveness. We also recommend additional research in this area. Keywords: feedback tools, self-assessment of performance, self-directed learning with feedback, feedback and self-assessment, video review of performance with feedback Dovepress submit your manuscript | www.dovepress.com

Research paper thumbnail of The Lived Experience and Training Needs of Librarians Serving at the Clinical Point-of-Care

Medical reference services quarterly, 2015

This study examines the emotional experiences and perceptions of librarians embedded into clinica... more This study examines the emotional experiences and perceptions of librarians embedded into clinical care teams and how those perceptions affect their training and preparation needs. Qualitative research methodologies were applied to textual data drawn from focus groups (n = 21), interviews (n = 2), and an online survey (n = 167), supplemented by quantitative survey data. Phenomenological results show librarians experience strongly affective responses to clinical rounding. Important factors include personal confidence; relationships with team members, patients, and families; and the stressful environment. Analysis of librarians' perceived educational needs indicates that training must address specialized subjects including medical knowledge, clinical culture, and institutional politics.

Research paper thumbnail of Hepatotoxicity from antituberculous therapy in the elderly: A systematic review

Tuberculosis (Edinburgh, Scotland), Jan 18, 2014

Elderly persons have the highest rates of tuberculosis (TB) in the United States compared to all ... more Elderly persons have the highest rates of tuberculosis (TB) in the United States compared to all other age groups. A systematic literature review was conducted to determine if older age was a risk factor for hepatotoxicity resulting from treatment with first-line drugs used to treat active (TB) and latent tuberculosis (LTBI). A systematic review of MEDLINE, Cochrane Controlled Trial Registry, CINAHL(®), and Science Citation Index Expanded (from 1970 to 2011) was performed to determine the risk of hepatotoxicity, comparing those over 60 with those under 60. A meta-analysis was performed using a random effects model along with log odds ratios and the chi-square test. Thirty-eight studies (40,034 participants; 1208 cases of hepatotoxicity) met the selection criteria. For active TB, an overall mean effect of 0.277 (p = 0.024, 95% CI: 0.037-0.517) was observed, which is equivalent to an odds ratio of 1.32 (95% CI: 1.04-1.68). For LTBI, an overall mean effect of 1.42 (p < 0.001, 95% CI...

Research paper thumbnail of A systematic review of emergency department point-of-care cardiac markers and efficiency measures

Point of Care, 2009

Advertisement. Close Window. Close Window. Thank you for choosing to subscribe to the eTOC for Po... more Advertisement. Close Window. Close Window. Thank you for choosing to subscribe to the eTOC for Point of Care. Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed ...

Research paper thumbnail of The Use of Research Electronic Data Capture (REDCap) Software to Create a Database of Librarian-Mediated Literature Searches

Medical Reference Services Quarterly, 2014

Expert-mediated literature searching, a keystone service in biomedical librarianship, would benef... more Expert-mediated literature searching, a keystone service in biomedical librarianship, would benefit significantly from regular methodical review. This article describes the novel use of Research Electronic Data Capture (REDCap) software to create a database of literature searches conducted at a large academic health sciences library. An archive of paper search requests was entered into REDCap, and librarians now prospectively enter records for current searches. Having search data readily available allows librarians to reuse search strategies and track their workload. In aggregate, this data can help guide practice and determine priorities by identifying users&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; needs, tracking librarian effort, and focusing librarians&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; continuing education.

Research paper thumbnail of Assessing learners’ needs

Oxford Textbook of Medical Education, 2013

Research paper thumbnail of Changing the Face of Reference: Adapting Biomedical and Health Information Services for the Classroom, Clinic, and Beyond

Medical Reference Services Quarterly, 2012

This paper describes how the reference department at a large academic health sciences library evo... more This paper describes how the reference department at a large academic health sciences library evolved to address the clinical and research information needs of the parent organization without losing its close connections to the classroom and curriculum. Closing the reference desk, moving to on-call and house call models, designing positions such as clinical research librarian and basic biomedical sciences librarian, finding alternative funding to grow the department, providing technology and training to facilitate librarians' work, and developing programming for and taking advice from library clients facilitated efforts to create a relevant presence and solidify the library's place in the university community.

Research paper thumbnail of Using the literature to evaluate diagnostic tests: amylase or lipase for diagnosing acute pancreatitis?

Journal of the Medical Library Association, 2007

Research paper thumbnail of Replication of Influenza A Viruses in an Avian Macrophage Cell Line

Journal of General Virology, 1991

Research paper thumbnail of Introducing Protein Data Bank, Molecular Modeling Database, and Cn3D

Journal of Electronic Resources in Medical Libraries, 2006

... viewers Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Re-search I... more ... viewers Jennifer A. Lyon, MS, MLIS (jennifer.lyon@vanderbilt.edu) is Coordinator, Re-search Informatics Consult Service, Eskind Biomedical Library, Vanderbilt University Medical Center, Nashville, TN 37232-8340. Michele ...

Research paper thumbnail of Management of penetrating neck injury in the emergency department: a structured literature review

Emergency Medicine Journal, 2008

The management of patients with penetrating neck injuries in the prehospital setting and in the e... more The management of patients with penetrating neck injuries in the prehospital setting and in the emergency department has evolved with regard to the necessity for spinal immobilisation and the use of multidetector computed tomographic (MDCT) imaging. Questions also arise as to choices of securing a threatened or compromised airway. A structured review of the medical literature was conducted to provide current recommendations for the management of patients with penetrating neck injury. Databases for PubMed, MEDLINE, CINAHL and Cochrane EBM Reviews were electronically searched using the subject headings &quot;penetrating neck injury&quot;, &quot;penetrating neck trauma&quot;, &quot;cervical immobilization&quot;, &quot;multi-detector CTA&quot; and &quot;airway management&quot;. The results generated by the search were limited to English language articles and reviewed for relevance to the topic. 122 citations were identified that met the criteria for emphasis on emergency department care, cervical spine immobilisation, use of multidetector CT angiography or airway management. After excluding case series, non-peer reviewed articles and editorials, 20 articles were identified and reviewed. The current literature suggests that prehospital cervical immobilisation may not be necessary unless the patient has focal neurological deficits. Studies show that patients with penetrating neck trauma who are haemodynamically stable and exhibit no &quot;hard signs&quot; of vascular injury may be evaluated initially by MDCT imaging even when platysma violation is present. Airway management is evolving, but traditional laryngoscopy continues to be the mainstay of airway stabilisation.

Research paper thumbnail of Inhibition of Nitric Oxide Induction from Avian Macrophage Cell Lines by Influenza Virus

Avian Diseases, 1993

The virulent avian influenza virus A/Ty/Ont/7732/66 (H5N9) (Ty/Ont) causes a rapid destruction of... more The virulent avian influenza virus A/Ty/Ont/7732/66 (H5N9) (Ty/Ont) causes a rapid destruction of lymphoid cells in infected birds. Avian macrophage cell lines, HD11 and MQ-NCSU, support productive replication of Ty/Ont and other influenza viruses. Therefore, the ability of these cell lines to produce nitric oxide (NO), a potentially cytotoxic mediator, in response to infection with Ty/Ont was examined. Although treatment with bacterial lipopolysaccharides (LPS) resulted in high NO levels, infection of macrophages with Ty/Ont resulted in NO levels lower than NO levels in untreated cells. Furthermore, Ty/Ont was able to inhibit the positive response to LPS in cultures simultaneously treated with LPS and virus. However, inactivated influenza virus did not exhibit this inhibitory effect. Different strains of influenza virus varied in their ability to inhibit NO production by the macrophages; this may be related to the level of virus replication in these cells. These data suggest that the ability of the avian macrophage to activate the NO synthesis pathway is seriously impaired by infection with virulent influenza viruses such as Ty/Ont.

Research paper thumbnail of Agreement of Decision Analyses and Subsequent Clinical Studies in Infectious Diseases

The American Journal of Medicine, 2007

Purpose: Decision analysis techniques can compare management strategies when there are insufficie... more Purpose: Decision analysis techniques can compare management strategies when there are insufficient data from clinical studies to guide decision-making. We compared the outcomes of decision analyses and subsequent clinical studies in the infectious disease literature to assess the validity of the conclusions of the decision analyses.