Rg Gibson - Profile on Academia.edu (original) (raw)
Papers by Rg Gibson
Annals of The Association of American Geographers, 2001
In this article, I reflect upon and attempt to understand the changing theoretical nature of post... more In this article, I reflect upon and attempt to understand the changing theoretical nature of post -World War II Anglo-American economic geography. In particular, I contrast the kind of theorizing that first occurred in the discipline during the 1950s with the very different kind now carried out under what has been called the "cultural turn" or the "new economic geography." I argue that, during this transition, not only did the use of specific theories alter, but the very idea and practice of theorization also changed. I characterize the phases of this movement by using the terms "epistemological" and "hermeneutic theorizing," defined on the basis of works by pragmatist philosopher Richard Rorty and science studies writer Donna Haraway. I argue that "epistemological theorizing" best describes the first period of theorization in the discipline around the quantitative revolution of the late 1950s and early 1960s, and that it is bound by the quest for accurate (mirror) representation. In contrast, hermeneutic theorizing describes the kind of theorizing found in the new economic geography, marked by an interpretive mode of inquiry that is reflexive, open-ended, and catholic in its theoretical sources.
Hydrobiologia, 2009
The purpose of this present study was to use the growth rates, RNA–DNA ratio and morphometric (Fu... more The purpose of this present study was to use the growth rates, RNA–DNA ratio and morphometric (Fulton’s K) condition indices measured on 0-group juveniles European flounder, as a means of comparing the quality of estuarine nursery habitats. The Seine estuary, heavily impacted by manmade modifications and one of the most contaminated in Europe, was compared to two smaller estuaries considered as clean (low domestic, agricultural and industrial effluents). Indicators of human disturbance (sediment chemical contaminants) as well as biotic data (macrobenthos abundances) were used to establish between-site differences in environmental quality. The abundance of macrobenthos (potential preys for juvenile) was high and not significantly different among the three estuaries confirming the important role played by estuaries as feeding grounds. Sediment metal concentrations (Cd, Cr, Cu, Pb, Zn) were significantly higher in the Seine than in the Canche and Authie estuaries. Otolith growth was closely related to somatic fish growth, and we used daily otolith increments from the previous 10 days before capture as an indicator of 0-group flounder recent growth (RG). RG did not vary significantly among flounders from the Canche and Authie estuaries and individuals from the Seine had slower RG. RNA–DNA ratio and K values were also significantly lower in individuals from the Seine compared to those of the Authie or the Canche. Pollution (e.g. metal contaminants) is the most likely cause of growth and condition differences among estuaries. The results of this study suggest that habitat-specific fish growth and condition are useful proxies for habitat quality since they integrate the effect of multiple environmental factors.
British Journal of Cancer, 1991
Photodynamic therapy (PDT) is efficacious in the treatment of small malignant lesions when all ce... more Photodynamic therapy (PDT) is efficacious in the treatment of small malignant lesions when all cells in the tumour receive sufficient drug, oxygen and light to induce a photodynamic effect capable of complete cytotoxicity. In large tumours, only partial effectiveness is observed presumably because of insufficient light penetration into the tissue. The heterogeneity of the metabolic response in mammary tumours following PDT has been followed in vivo using localised phosphorus NMR spectroscopy. Alterations in nucleoside triphosphates (NTP), inorganic phosphate (Pi) and pH within localised regions of the tumour were monitored over 24-48 h following PDT irradiation of the tumour. Reduction of NTP and increases in P, were observed at 4-6 h after PDT irradiation in all regions of treated tumours. The uppermost regions of the tumours (those nearest the skin surface and exposed to the greatest light fluence) displayed the greatest and most prolonged reduction of NTP and concomitant increase in Pi resulting in necrosis. The metabolite concentrations in tumour regions located towards the base of the tumour returned to near pre-treatment levels by 24-48 h after irradiation. The ability to follow heterogeneous metabolic responses in situ provides one means to assess the degree of metabolic inhibition which subsequently leads to tumour necrosis.
Annals of The Association of American Geographers, 2001
In this article, I reflect upon and attempt to understand the changing theoretical nature of post... more In this article, I reflect upon and attempt to understand the changing theoretical nature of post -World War II Anglo-American economic geography. In particular, I contrast the kind of theorizing that first occurred in the discipline during the 1950s with the very different kind now carried out under what has been called the "cultural turn" or the "new economic geography." I argue that, during this transition, not only did the use of specific theories alter, but the very idea and practice of theorization also changed. I characterize the phases of this movement by using the terms "epistemological" and "hermeneutic theorizing," defined on the basis of works by pragmatist philosopher Richard Rorty and science studies writer Donna Haraway. I argue that "epistemological theorizing" best describes the first period of theorization in the discipline around the quantitative revolution of the late 1950s and early 1960s, and that it is bound by the quest for accurate (mirror) representation. In contrast, hermeneutic theorizing describes the kind of theorizing found in the new economic geography, marked by an interpretive mode of inquiry that is reflexive, open-ended, and catholic in its theoretical sources.
Hydrobiologia, 2009
The purpose of this present study was to use the growth rates, RNA–DNA ratio and morphometric (Fu... more The purpose of this present study was to use the growth rates, RNA–DNA ratio and morphometric (Fulton’s K) condition indices measured on 0-group juveniles European flounder, as a means of comparing the quality of estuarine nursery habitats. The Seine estuary, heavily impacted by manmade modifications and one of the most contaminated in Europe, was compared to two smaller estuaries considered as clean (low domestic, agricultural and industrial effluents). Indicators of human disturbance (sediment chemical contaminants) as well as biotic data (macrobenthos abundances) were used to establish between-site differences in environmental quality. The abundance of macrobenthos (potential preys for juvenile) was high and not significantly different among the three estuaries confirming the important role played by estuaries as feeding grounds. Sediment metal concentrations (Cd, Cr, Cu, Pb, Zn) were significantly higher in the Seine than in the Canche and Authie estuaries. Otolith growth was closely related to somatic fish growth, and we used daily otolith increments from the previous 10 days before capture as an indicator of 0-group flounder recent growth (RG). RG did not vary significantly among flounders from the Canche and Authie estuaries and individuals from the Seine had slower RG. RNA–DNA ratio and K values were also significantly lower in individuals from the Seine compared to those of the Authie or the Canche. Pollution (e.g. metal contaminants) is the most likely cause of growth and condition differences among estuaries. The results of this study suggest that habitat-specific fish growth and condition are useful proxies for habitat quality since they integrate the effect of multiple environmental factors.
British Journal of Cancer, 1991
Photodynamic therapy (PDT) is efficacious in the treatment of small malignant lesions when all ce... more Photodynamic therapy (PDT) is efficacious in the treatment of small malignant lesions when all cells in the tumour receive sufficient drug, oxygen and light to induce a photodynamic effect capable of complete cytotoxicity. In large tumours, only partial effectiveness is observed presumably because of insufficient light penetration into the tissue. The heterogeneity of the metabolic response in mammary tumours following PDT has been followed in vivo using localised phosphorus NMR spectroscopy. Alterations in nucleoside triphosphates (NTP), inorganic phosphate (Pi) and pH within localised regions of the tumour were monitored over 24-48 h following PDT irradiation of the tumour. Reduction of NTP and increases in P, were observed at 4-6 h after PDT irradiation in all regions of treated tumours. The uppermost regions of the tumours (those nearest the skin surface and exposed to the greatest light fluence) displayed the greatest and most prolonged reduction of NTP and concomitant increase in Pi resulting in necrosis. The metabolite concentrations in tumour regions located towards the base of the tumour returned to near pre-treatment levels by 24-48 h after irradiation. The ability to follow heterogeneous metabolic responses in situ provides one means to assess the degree of metabolic inhibition which subsequently leads to tumour necrosis.