jimmy tang | The Hong Kong Polytechnic University (original) (raw)

Papers by jimmy tang

ew languages GraphQL, Metal Shading Language, PlantUML, Properties, Umka. Better consistency with... more ew languages GraphQL, Metal Shading Language, PlantUML, Properties, Umka. Better consistency with upper- and lowercase file names on Windows. Bug fixes for --force-lang-def, --csv-delimiter, --vcs=git with --max-file-size, --unicode, --ignored (directory names no longer appear).

Changes csvtk v0.19.1 <code>csvtk</code>: fix checking file existence. show friendly ... more Changes csvtk v0.19.1 <code>csvtk</code>: fix checking file existence. show friendly error message when giving empty field like <code>csvtk cut -f a, b</code>. <code>csvtk summary</code>: fix err of q1 and q3. #90 <code>csvtk version</code>: making checking update optional. Links: Tips run <code>csvtk version</code> to check update !!! run <code>csvtk genautocomplete</code> to update Bash completion !!! OS Arch File, 中国镜像 Download Count Linux 32-bit csvtk_linux_386.tar.gz, 中国镜像 Linux 64-bit csvtk_linux_amd64.tar.gz, 中国镜像 OS X 32-bit csvtk_darwin_386.tar.gz, 中国镜像 OS X 64-bit csvtk_darwin_amd64.tar.gz, 中国镜像 Windows 32-bit csvtk_windows_386.exe.tar.gz, 中国镜像 Windows 64-bit</strong&g...

1 This brief was written by Emily Bosch, Abdoulaye Fabregas, and Franziska Fischer. Feedback and ... more 1 This brief was written by Emily Bosch, Abdoulaye Fabregas, and Franziska Fischer. Feedback and comments were gratefully received from Andrea Ries (Swiss Agency for Development and Cooperation); Silke Weinlich, Erik Lundsgaarde, and Max Baumann (German Development Institute); Global Affairs Canada; the French Ministry of European and Foreign Affairs; Nick Rene Hartmann, Janil Greenaway, Jimmy Tang, and Rod Mamudi (UNDP); and the World Bank Group. The paper also benefited from the input of OECD colleagues: Marisa Berbegal-Ibanez, Olivier Cattaneo, Claudio Cerabino, John Egan, Cyprien Fabre, Mags Gaynor, Jieun Kim, Anita King, Rahul Malhotra, Valentina Orru, Ashley Palmer, Santhosh Persaud, and MOPAN. Earmarked funding to multilateral organisations: how is it used and what constitutes good practice?

Sustainability is one of today's primary engineering objectives. This principle involves system d... more Sustainability is one of today's primary engineering objectives. This principle involves system design that minimizes environmentally harmful energy emissions and resource consumption, and maximizes renewable energy practices [1]. Communication antennas transmit wireless signals that can be converted into usable energy. The Rectenna system described in this report, shown in Figure 1, was designed to accomplish this energy conversion, with 5dBm (316µW) minimum power at the rectifier input. Since typical ambient signal power is in the 70dBm (0.1nW) range, the proposed system could only convert passive, relatively highpower microwave band AC signals to DC. The Rectenna system was designed for 1.9GHz signal reception; however, the greatest ambient 1.9GHz signal power measured in Cal Poly's Microwave Lab was in the 75dBm (31pW) to 70dBm (100pW) range, shown in Table 1. The team provided an external 1.9GHz source (20dBm to 3dBm) to verify the design.

Transnational Corporations Review, 2012

Since the beginning of the economic reform in 1978, China has made remarkable achievement in attr... more Since the beginning of the economic reform in 1978, China has made remarkable achievement in attracting foreign direct investment (FDI) as well as its outward FDI to serve its important role as a part of the country’s reform and opening-up to the outside world. FDI to China significantly promotes its reform and opening-up while this also creates a condition for its attraction in return. China’s opening-up to the outside world has not had any available reference model, and there has been no ways of emulating other countries’ experience. What has been done instead is to grope forward, to learn from various lessons, and to perfect its practice based on the conditions in China. Despite its arduous exploratory journey, China’s FDI has shown the world its historic experiments by virtue of its achievements. With China entering a new stage in FDI in the 21 century, it is of great practical importance and theoretical value to review and explore the practice by applying a scientific and histo...

The stated heat recovery efficiency of HRV and ERV units in North American passive houses is depe... more The stated heat recovery efficiency of HRV and ERV units in North American passive houses is dependent on the testing procedures and calculation methods established by several pertinent performance testing standards. This project highlights major differences between the applicable HRV/ERV standards for North American passive houses: the European Passive House Institute standard, the Canadian CSA-439-09 standard, and the American HVI-920 standard. It further examines the proposed PHIUS protocol which established ɳPHUIS, a modified HRV/ERV heat recovery efficiency rating to more accurately reflect the North American climate. Simulations were performed to quantify its effect on the modelled annual heat demand for 31 certified passive houses. The results yielded two key findings. First, the margin of error for the new rating, ɳPHUIS, relative to the existing rating, Ɛ, is a function of the regional climate given by the equation: y = 0.00001x + 0.0012. Locations with a colder climate hav...

British Dental Journal, 2017

Journal of Integrated Design and Process Science, Apr 1, 1999

Proceedings of ICC'97 - International Conference on Communications

Three-Dimensional Imaging, Interaction, and Measurement, 2011

The detection of objects on a given road path by vehicles equipped with range measurement devices... more The detection of objects on a given road path by vehicles equipped with range measurement devices is important to many civilian and military applications such as obstacle avoidance in autonomous navigation systems. In this thesis, we develop a method to detect objects of a specific size lying on a road using an acquisition vehicle equipped with forward looking Light Detection And Range (LiDAR) sensors and inertial navigation system. We use GPS data to accurately place the LiDAR points in a world map, extract point cloud clusters protruding from the road, and detect objects of interest using weighted random forest trees. We show that our proposed method is effective in identifying objects for several road datasets collected with various object locations and vehicle speeds.

Digital Repository of Ireland Series, 2013

Journal of Applied Physics, 2010

We have demonstrated a postprocessed complementary metal oxide semiconductor ͑CMOS͒ integrated ci... more We have demonstrated a postprocessed complementary metal oxide semiconductor ͑CMOS͒ integrated circuit ͑IC͒ capable of on-chip magnetic separation, i.e., removing via magnetic forces the nonspecifically bound magnetic beads from the detection area on the surface of the chip. Initially, 4.5 m wide superparamagnetic beads sedimenting out of solution due to gravity were attracted to the detection area by a magnetic concentration force generated by flowing current through a conductor embedded in the IC. After sedimentation, the magnetic beads that did not bind strongly to the functionalized surface of the IC through a specific biochemical complex were removed by a magnetic separation force generated by flowing current through another conductor placed laterally to the detection area. As the spherical bead pivoted on the surface of the chip, the lateral magnetic force was further amplified by mechanical leveraging, and 50 mA of current flowing through the separation conductor placed 18 m away from the bead resulted in 7.5 pN of tensile force on the biomolecular tether immobilizing the bead. This force proved high enough to break nonspecific interactions while leaving specific antibody-antigen bonds intact. A sandwich capture immunoassay on purified human immunoglobulin G showed strong correlation with a control enzyme linked immunosorbent assay and a detection limit of 10 ng/ml or 70 pM. The beads bound to the detection area after on-chip magnetic separation were detected optically. To implement a fully integrated molecular diagnostics platform, the on-chip magnetic separation functionality presented in this work can be readily combine with state-of-the art CMOS-based magnetic bead detection technology.

Nucleosides and Nucleotides, 1997

Several sulfur-transfer reagents have been evaluated for large scale synthesis of oligonucleotide... more Several sulfur-transfer reagents have been evaluated for large scale synthesis of oligonucleotide phosphorothioate analogues, in which 3-ethoxy-1, 2-dithiazoline-5-one (EDITH, 5) shows potential as an alternative to Beaucage reagent.

Vaccine, 2005

CpG DNA induces potent Th1 immune responses through Toll-like receptor 9. In the present study, w... more CpG DNA induces potent Th1 immune responses through Toll-like receptor 9. In the present study, we used oligonucleotides consisting of a novel 3-3-linked structure and synthetic stimulatory motifs, referred as second-generation immunomodulatory oligonucleotides (IMOs). The stimulatory motifs included: CpR, YpG, or R pG (R = 2-deoxy-7-deazaguanosine, Y = 2-deoxy-5-hydroxy-cytidine, and R = 1-[2-deoxy-␤-d-ribofuranosyl]-2-oxo-7-deaza-8-methyl-purine). We evaluated the stability of orally administered IMOs in the gastrointestinal (GI) environment and their ability to induce mucosal immune responses in mice, and compared these characteristics with those of a conventional CpG DNA. The IMOs were significantly more stable than CpG DNA following oral administration, and IMOs induced stronger local and systemic immune responses as determined by MIP-1␤, MCP-1, IP-10, and IL-12 production. Mice orally immunized with ovalbumin (OVA) and IMO had higher levels of IgG2a antibodies in serum and IgA antibodies in intestinal mucosa than did mice immunized with OVA and CpG DNA. These studies demonstrate that IMOs are more stable than CpG DNA in the GI tract and can induce more potent mucosal Th1 adjuvant responses. IMOs may prove to be effective oral adjuvants, able to promote strong systemic and mucosal immune responses to oral vaccines and antigens for therapeutic and prophylactic applications.

Tetrahedron Letters, 1998

... of Oligonueleotide Phosphorothioate Analogues Using Bis(ethoxythiocarbonyi)tetrasulfide as a ... more ... of Oligonueleotide Phosphorothioate Analogues Using Bis(ethoxythiocarbonyi)tetrasulfide as a New SulfurTransfer Reagent Zhaoda Zhang.1, Alexandra Nichols, Mazen Alsbeti ... 3. Kamer, PCJ; Roelen, HCPF; van den Elst, H.; van der Marel, GA; van Boom, JH Tetrahedron Lett. ...

Proceedings of the National Academy of Sciences, 2003

Bacterial and synthetic DNAs containing CpG dinucleotides in specific sequence contexts activate ... more Bacterial and synthetic DNAs containing CpG dinucleotides in specific sequence contexts activate the vertebrate immune system through Toll-like receptor 9 (TLR9). In the present study, we used a synthetic nucleoside with a bicyclic heterobase [1-(2′-deoxy-β- d -ribofuranosyl)-2-oxo-7-deaza-8-methyl-purine; R] to replace the C in CpG, resulting in an RpG dinucleotide. The RpG dinucleotide was incorporated in mouse- and human-specific motifs in oligodeoxynucleotides (oligos) and 3′-3-linked oligos, referred to as immunomers. Oligos containing the RpG motif induced cytokine secretion in mouse spleen-cell cultures. Immunomers containing RpG dinucleotides showed activity in transfected-HEK293 cells stably expressing mouse TLR9, suggesting direct involvement of TLR9 in the recognition of RpG motif. In J774 macrophages, RpG motifs activated NF-κB and mitogen-activated protein kinase pathways. Immunomers containing the RpG dinucleotide induced high levels of IL-12 and IFN-γ, but lower IL-6 ...

Proceedings of the National Academy of Sciences, 2005

Bacterial DNA and synthetic oligomers containing CpG dinucleotides activate the immune system thr... more Bacterial DNA and synthetic oligomers containing CpG dinucleotides activate the immune system through Toll-like receptor (TLR) 9. Here, we compare the immunostimulatory activity of three immunomers with different nucleotide sequences containing a synthetic cytosine-phosphate-2′-deoxy-7-deazaguanosine dinucleotide (CpR), called immunomodulatory oligonucleotides (IMOs), in mouse, human, and monkey systems. IMOs induced IL-12 and IFN-γ secretion more than a control non-CpG IMO in mice. All three IMOs activated HEK293 cells expressing TLR9 but not TLR3, -7, or -8. IMOs induced human B-cell proliferation and enhanced expression of CD86 and CD69 surface markers on B cells. The three IMOs induced CD86 expression on human plasmacytoid dendritic cells, but only IMOs that contained a 5′-terminal TCR nucleotide sequence induced IFN-α secretion. A sequence that forms a duplex structure also was required for IFN-α induction in human peripheral blood mononuclear cell cultures. IMOs induced chemok...

Organic & Biomolecular Chemistry, 2013