Dr osarenkhoe John | Igbinedion university, Okada, Edo, Nigeria (original) (raw)
Papers by Dr osarenkhoe John
ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We ... more ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We report two cases managed in a tertiary facility in Nigeria. The first case is a 31-year-old woman who came to the hospital with overt symptoms of heart failure. Color Doppler showed a left to right shunt in the inter-atrial septum (Ostium Primum type). She subsequently improved with anti-failure regimen and anticoagulants. The second case is a 32-year-old man who presented with easy fatigability of four months. Transthoracic echocardiogram revealed a mid-inter-atrial septal defect (Ostium Secundum type) with dilated heart chambers. He is for surgery pending when finances permit.
Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA b... more Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA both structurally and functionally posing clinically signicant risk to patients. LA size assessment until recently was limited to determination of LA linear diameter and much has not been elucidated with respect to left atrial volume as a surrogate for LA function. It is therefore important to see how LA size (linear diameter and volume) relate to LV function (Systolic and Diastolic) among hypertensive subgroups and normotensive subjects. To compare hypertensive with normotensive using the echocardiographic 2D Objectives: Methods: /M mode/Velocity parameters It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients and 100 normotensive controls (matched for age and sex in a 2:1 ratio) were recruited from the cardiology clinics using systematic sampling method. The mean age of the study Results: population was 58.7 ±13.96 (58.42±13.29 for Hypertensives and 59.26±15.27 for Controls) years while the median age was 59years.The female to male ratio was 1.06 among cases and 1.27 among the controls. Majority of the cases had isolated diastolic dysfunction n=149 (74.5%), thirty six (18%) had normal diastolic and systolic functions while 7.5% had combined systolic and diastolic dysfunction (n=15). The LA size (volumes and linear diameter) was signicantly larger in the hypertensive group compared to the control arm. LA reservoir and contractile functions were found to be signicantly higher in the hypertensive cohort while the conduit function was found to be lower among the hypertensive subjects. LA volumes correlated signicantly with E/E'. Among Cases with Isolated LV Diastolic Dysfunction, LV mass correlated signicantly with all measurements of LA size. LA minimum volume correlated signicantly with E/A ratio. Among cases with LV Systolic and Diastolic Dysfunction, LA pre A wave volume correlated signicantly with LV mass. LA volumes correlated better than LA linear diameter with specic parameters of LV diastolic dysfunction among all groups of cases and controls. There was no signicant correlation between age, body mass index versus LA linear diameter and volumes among cases with Normal LV Systolic and Diastolic Function, isolated LV diastolic dysfunction and the group with both LV Systolic and Diastolic Dysfunction. There was signicant association between ECG and Echocardiographic LA enlargement. LA maximum volume correlated signicantly with average systolic blood pressure, pulse pressure and mean arterial pressure. Conclusion: Hypertensive patients have larger LA volumes than normotensive controls. LA volumes correlate better than LA linear diameter with diastolic function variables. It is therefore expedient to use LA volumes routinely in assessing LA size as it may detect early and subtle changes in LA size and function
PERCEIVED SOCIAL SUPPORT IN RELATION TO QUALITY OF LIFE AMONG SCHOOL TEACHERS
Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA b... more Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA both structurally and functionally posing clinically signicant risk to patients. LA size assessment until recently was limited to determination of LA linear diameter and much has not been elucidated with respect to left atrial volume as a surrogate for LA function. It is therefore important to see how LA size (linear diameter and volume) relate to LV function (Systolic and Diastolic) among hypertensive subgroups and normotensive subjects. To compare hypertensive with normotensive using the echocardiographic 2D Objectives: Methods: /M mode/Velocity parameters It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients and 100 normotensive controls (matched for age and sex in a 2:1 ratio) were recruited from the cardiology clinics using systematic sampling method. The mean age of the study Results: population was 58.7 ±13.96 (58.42±13.29 for Hyp...
International Journal of Health Sciences
Purpose: Hypertension is known to cause changes in the LV that impact negatively on the LA both s... more Purpose: Hypertension is known to cause changes in the LV that impact negatively on the LA both structurally and functionally posing clinically significant risk to patients. LA size assessment until recently was limited to determination of LA linear diameter and much has not been elucidated with respect to left atrial volume (indices) and cardiac indices as surrogates for LA and cardiac function. It is therefore important to see how LA indices (size, linear diameter and volume) cardiac indices relate to LV diastolic function among hypertensive subjects. To compare left atria indices with left ventricular function/dysfunction among hypertensive Methodology: It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients were recruited from the cardiology clinics using systematic sampling method. Results: Majority of the cases had isolated diastolic dysfunction n=149 (74.5%), thirty-six (18%) had normal diastolic and systolic functions while 7....
Trends in Internal Medicine
ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We ... more ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We report two cases managed in a tertiary facility in Nigeria. The first case is a 31-year-old woman who came to the hospital with overt symptoms of heart failure. Color Doppler showed a left to right shunt in the inter-atrial septum (Ostium Primum type). She subsequently improved with anti-failure regimen and anticoagulants. The second case is a 32-year-old man who presented with easy fatigability of four months. Transthoracic echocardiogram revealed a mid-inter-atrial septal defect (Ostium Secundum type) with dilated heart chambers. He is for surgery pending when finances permit.
International Journal of Health Sciences
Purpose: To compare LA indices and cardiac indices among hypertensive with left ventricular diast... more Purpose: To compare LA indices and cardiac indices among hypertensive with left ventricular diastolic dysfunction Methodology: It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients were recruited from the cardiology clinics using systematic sampling method. Results: The mean age of the study population was 58.7 ±13.96 (58.42±13.29 for Hypertensives) years while the median age was 59years.The female to male ratio was 1:6. Majority of the cases had isolated diastolic dysfunction n=149 (74.5%), thirty-six (18%) had normal diastolic and systolic functions while 7.5% had combined systolic and diastolic dysfunction (n=15). Left atrial maximum volume correlated significantly with E/E Prime (P= 0.003) and E/A Ratio (P= 0.003). While Left atrial pre-A wave volume (P=0.025), Left atrial diameter did not correlate with IVRT, E/E’, E/A ratio. Unique Contribution to Theory, Policy and Practice: Among the hypertensive patients E/E’ significantly ...
ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We ... more ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We report two cases managed in a tertiary facility in Nigeria. The first case is a 31-year-old woman who came to the hospital with overt symptoms of heart failure. Color Doppler showed a left to right shunt in the inter-atrial septum (Ostium Primum type). She subsequently improved with anti-failure regimen and anticoagulants. The second case is a 32-year-old man who presented with easy fatigability of four months. Transthoracic echocardiogram revealed a mid-inter-atrial septal defect (Ostium Secundum type) with dilated heart chambers. He is for surgery pending when finances permit.
Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA b... more Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA both structurally and functionally posing clinically signicant risk to patients. LA size assessment until recently was limited to determination of LA linear diameter and much has not been elucidated with respect to left atrial volume as a surrogate for LA function. It is therefore important to see how LA size (linear diameter and volume) relate to LV function (Systolic and Diastolic) among hypertensive subgroups and normotensive subjects. To compare hypertensive with normotensive using the echocardiographic 2D Objectives: Methods: /M mode/Velocity parameters It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients and 100 normotensive controls (matched for age and sex in a 2:1 ratio) were recruited from the cardiology clinics using systematic sampling method. The mean age of the study Results: population was 58.7 ±13.96 (58.42±13.29 for Hypertensives and 59.26±15.27 for Controls) years while the median age was 59years.The female to male ratio was 1.06 among cases and 1.27 among the controls. Majority of the cases had isolated diastolic dysfunction n=149 (74.5%), thirty six (18%) had normal diastolic and systolic functions while 7.5% had combined systolic and diastolic dysfunction (n=15). The LA size (volumes and linear diameter) was signicantly larger in the hypertensive group compared to the control arm. LA reservoir and contractile functions were found to be signicantly higher in the hypertensive cohort while the conduit function was found to be lower among the hypertensive subjects. LA volumes correlated signicantly with E/E'. Among Cases with Isolated LV Diastolic Dysfunction, LV mass correlated signicantly with all measurements of LA size. LA minimum volume correlated signicantly with E/A ratio. Among cases with LV Systolic and Diastolic Dysfunction, LA pre A wave volume correlated signicantly with LV mass. LA volumes correlated better than LA linear diameter with specic parameters of LV diastolic dysfunction among all groups of cases and controls. There was no signicant correlation between age, body mass index versus LA linear diameter and volumes among cases with Normal LV Systolic and Diastolic Function, isolated LV diastolic dysfunction and the group with both LV Systolic and Diastolic Dysfunction. There was signicant association between ECG and Echocardiographic LA enlargement. LA maximum volume correlated signicantly with average systolic blood pressure, pulse pressure and mean arterial pressure. Conclusion: Hypertensive patients have larger LA volumes than normotensive controls. LA volumes correlate better than LA linear diameter with diastolic function variables. It is therefore expedient to use LA volumes routinely in assessing LA size as it may detect early and subtle changes in LA size and function
PERCEIVED SOCIAL SUPPORT IN RELATION TO QUALITY OF LIFE AMONG SCHOOL TEACHERS
Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA b... more Introduction: Hypertension is known to cause changes in the LV that impact negatively on the LA both structurally and functionally posing clinically signicant risk to patients. LA size assessment until recently was limited to determination of LA linear diameter and much has not been elucidated with respect to left atrial volume as a surrogate for LA function. It is therefore important to see how LA size (linear diameter and volume) relate to LV function (Systolic and Diastolic) among hypertensive subgroups and normotensive subjects. To compare hypertensive with normotensive using the echocardiographic 2D Objectives: Methods: /M mode/Velocity parameters It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients and 100 normotensive controls (matched for age and sex in a 2:1 ratio) were recruited from the cardiology clinics using systematic sampling method. The mean age of the study Results: population was 58.7 ±13.96 (58.42±13.29 for Hyp...
International Journal of Health Sciences
Purpose: Hypertension is known to cause changes in the LV that impact negatively on the LA both s... more Purpose: Hypertension is known to cause changes in the LV that impact negatively on the LA both structurally and functionally posing clinically significant risk to patients. LA size assessment until recently was limited to determination of LA linear diameter and much has not been elucidated with respect to left atrial volume (indices) and cardiac indices as surrogates for LA and cardiac function. It is therefore important to see how LA indices (size, linear diameter and volume) cardiac indices relate to LV diastolic function among hypertensive subjects. To compare left atria indices with left ventricular function/dysfunction among hypertensive Methodology: It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients were recruited from the cardiology clinics using systematic sampling method. Results: Majority of the cases had isolated diastolic dysfunction n=149 (74.5%), thirty-six (18%) had normal diastolic and systolic functions while 7....
Trends in Internal Medicine
ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We ... more ASD is one of the most common asymptomatic congenital heart defects manifesting in adulthood. We report two cases managed in a tertiary facility in Nigeria. The first case is a 31-year-old woman who came to the hospital with overt symptoms of heart failure. Color Doppler showed a left to right shunt in the inter-atrial septum (Ostium Primum type). She subsequently improved with anti-failure regimen and anticoagulants. The second case is a 32-year-old man who presented with easy fatigability of four months. Transthoracic echocardiogram revealed a mid-inter-atrial septal defect (Ostium Secundum type) with dilated heart chambers. He is for surgery pending when finances permit.
International Journal of Health Sciences
Purpose: To compare LA indices and cardiac indices among hypertensive with left ventricular diast... more Purpose: To compare LA indices and cardiac indices among hypertensive with left ventricular diastolic dysfunction Methodology: It is an echocardiographic based descriptive cross-sectional study. A total of 200 hypertensive patients were recruited from the cardiology clinics using systematic sampling method. Results: The mean age of the study population was 58.7 ±13.96 (58.42±13.29 for Hypertensives) years while the median age was 59years.The female to male ratio was 1:6. Majority of the cases had isolated diastolic dysfunction n=149 (74.5%), thirty-six (18%) had normal diastolic and systolic functions while 7.5% had combined systolic and diastolic dysfunction (n=15). Left atrial maximum volume correlated significantly with E/E Prime (P= 0.003) and E/A Ratio (P= 0.003). While Left atrial pre-A wave volume (P=0.025), Left atrial diameter did not correlate with IVRT, E/E’, E/A ratio. Unique Contribution to Theory, Policy and Practice: Among the hypertensive patients E/E’ significantly ...