Begoña Olmedilla-alonso | CSIC (Consejo Superior de Investigaciones Científicas-Spanish National Research Council) (original) (raw)

Papers by Begoña Olmedilla-alonso

Nutrients

Higher salt (sodium) intake has been associated with higher blood pressure (BP). The degree of as... more Higher salt (sodium) intake has been associated with higher blood pressure (BP). The degree of association may be influenced by factors such as age, origin, and dietary components. This study aimed to evaluate the 24 h urinary sodium (Na) and potassium (K) excretion in normotensive and hypertensive Dominican adults and estimate their salt intake. 163 volunteers (18–80 years old) participated in a cross-sectional study. The 24 h Na and K urinary excretion were measured using an ion-selective electrode technique. Na and K urinary excretion (99.4 ± 46.5 and 35.0 ± 17.5 mmol/24 h) did not correlate with BP, except in the normotensive group, in which K correlated with SBP (0.249, p = 0.019). Na and K excretion were similar in normotensive and hypertensive subjects. When considering two age groups (18–45, 46–80 years), the Na-to-K molar ratio (3.1 ± 1.3) was higher in younger subjects (p = 0.040). Na-to-K ratio was associated with DBP in the total group (r = 0.153, p = 0.052), in the hype...

Higher salt (sodium) intake has been associated with a higher blood pressure (BP). The associatio... more Higher salt (sodium) intake has been associated with a higher blood pressure (BP). The association degree may be influenced by factors such as age, origin and dietary components. This study aimed to evaluate the 24-hours urinary sodium (Na) and potassium (K) excretion in normotensive and hypertensive Dominicans adults and estimate their salt intake. 163 volunteers (18-45, 46-80 years) participated in a cross-sectional study. 24-hours Na and K urinary excretion were measured using an ion selective electrode technique. Na and K urinary excretion (99.4±46.5 and 35.0±17.5 mmol/24h) did not correlated with BP, except in the normotensive group in which K correlated with SBP (0.249, p=0.019). Na and K excretion were similar for normo- and hypertensive subjects. Na-to-K molar ratio (3.1±1.3) was higher in younger subjects (p=0.040). Na-to-K ratio was associated with DBP in the total group (r=0.153, p=0.052), in the hypertensive group (r=0.395, p<0.001) and in the older group with SBP (0.350, p=0.002) and DBP (0.373, p<0.001). In the older group, Na-to-K ratio and DBP correlated after controlling for subjects with hypertension controlled by treatment (r=0.236, p=0.041). The Na-to-K ratio correlated, when salt intake was over 5g/d (52.2%), with SBP (rho=0.219, p=0.044) and DBP (rho=0.259, p=0.017). Determinants of BP were age-dependent and in younger subjects were: sex (SBP, beta: 14.02±2.87, p<0.001) and body mass index (BMI) (beta:-12.07±3.72, p=0.001, beta:9.44±2.87, p=0.001, for SBP and DBP, respectively) and, in the olders, the Na-to-K ratio, for SBP (beta:6.7±2.4, p=0.005) and DBP (beta:3.8±1.1, p<0.001). The mean Na and salt intakes (2.3 and 5.8 g/d) were slightly higher and K intake lower (1.4 g/d) than WHO recommendations.

Nutrients, May 18, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Journal of the Science of Food and Agriculture, Jun 2, 2014

BACKGROUND: Wild vegetables have traditionally been consumed as part of the Mediterranean diet, b... more BACKGROUND: Wild vegetables have traditionally been consumed as part of the Mediterranean diet, being valuable sources of nutrients and bioactive compounds. The objective of this work was to analyse the carotenoid content of the edible young shoots of four species (Asparagus acutifolius L., Humulus lupulus L., Bryonia dioica Jacq. and Tamus communis L.) as part of a wider study on the characterisation of the nutritional composition of wild edible plants commonly consumed in Spain. Samples were gathered from two locations in Central Spain for two consecutive years. RESULTS: Lutein, β-carotene, neoxanthin and violaxanthin were quantified by high-performance liquid chromatography with a photodiode array detector. Median concentration ranges (mg g −1 edible wet weight) were: β-carotene, 33.9-66.9; lutein, 54.4-191.3; neoxanthin, 51.7-173.7; and violaxanthin, 20.8-89.3. The highest carotenoid content was that of B. dioica (590.1 mg g −1) and the lowest was found in A. acutifolius (175.8 mg g −1). CONCLUSION: Our results show that these wild young shoots are richer sources of carotenoids than many of the commercially available leafy vegetables.

Journal of food and nutrition research, May 28, 2018

Antioxidant in vitro markers were used to evaluate the total antioxidant activity of ewe (whole a... more Antioxidant in vitro markers were used to evaluate the total antioxidant activity of ewe (whole and semi-skimmed) and cow's set yogurts. Results showed that cow set yogurt had significantly (p≤0.05) total higher antioxidant activity than ewe set yogurt and peptidic fraction had significant higher contribution to the total antioxidant activity compared to lipidic and/or phenolic fraction. However, when lipidic fraction was evaluated, ewe yogurt (whole and skimmed) had higher antioxidant activity than cow probably associated to the high levels of conjugated linoleic acid (CLA) in ewe milk. Although significant differences win cortisol levels were observed in certain groups of population studied (normal risk woman) regarding consume ewe yogurt, it is not possible to conclude a significant lowering effect of ewe yogurt on cortisol levels in general population.

Food Chemistry: X, Jun 1, 2020

Highlights • Nine carotenoids, including phytoene and phytofluene, quantified in red pepper.• Car... more Highlights • Nine carotenoids, including phytoene and phytofluene, quantified in red pepper.• Carotenoid concentrations did not vary significatively after 21 days under refrigeration.• The most abundant carotenoids in Lamuyo-peppers were capsanthin, β-carotene, lutein and zeaxanthin.

Journal of Functional Foods, Feb 1, 2023

Food chemistry advances, Jul 1, 2023

Elsevier eBooks, 2019

Fruit and vegetables supply nutrients and other bioactive compounds, including lutein and zeaxant... more Fruit and vegetables supply nutrients and other bioactive compounds, including lutein and zeaxanthin, to human diet. Macular pigment (MP) is composed of lutein and zeaxanthin, from dietary origin, and mesozeaxanthin. MP has been studied in relation with ocular health (visual function and risk of chronic eye diseases). This chapter focuses on the relationship between lutein and zeaxanthin intake from overall diet or from fruit and vegetables with the MPOD, and on the factors influencing the comparison of results across studies (i.e. methodological, subject-and food-related). Public health dietary recommendations encourage increased fruit and vegetable consumption, and certain scientific organism highlight the benefits of green-colored foods. However, the amount of dietary lutein and zeaxanthin is not the only determinant of increasing MPOD; in fact, their bioavailability from food matrixes is crucial. Several studies suggest that foods of red/orange color (mainly fruits) are better sources /contributors than those of green color.

biodisponibilidad de Carotenoides, faCtores que la determinan y métodos de estimaCión introducció... more biodisponibilidad de Carotenoides, faCtores que la determinan y métodos de estimaCión introducción Los carotenoides están presentes en muchos alimentos. Estudios in vitro e in vivo parecen indicar que podrían ser beneficiosos para la salud, aunque estos efectos protectores no han sido demostrados de forma contundente en humanos debido a las dificultades que entrañan estos estudios. Algunos de estos compuestos son precursores de la vitamina A. Se considera que los carotenoides de frutas y hortalizas pueden llegar a representar hasta 80-85% de la ingesta de vitamina A en algunas áreas. En cualquier caso, la actividad biológica de los carotenoides y compuestos derivados de ellos dependen más que de la cantidad consumida, de la absorbida y metabolizada por el organismo. El proceso de absorción de carotenoides es complejo y puede ser modificado por factores de diversa naturaleza. Este capítulo aborda el concepto de biodisponibilidad en su versión más amplia. Abunda en los factores que la determinan y los métodos para evaluarla. Capítulo 26 26. BiodisponiBilidad de carotenoides, factores que la determinan y métodos de estimación Alimento Bioaccesibilidad (%) Modelo in vitro con digestion gástrica e intestinal Referencia Tomate licopeno (1.4); β-caroteno (15.5); luteína (58.6); fitoeno (96.2) licopeno (79.4); β-caroteno (99.5); luteína (91.6)

Los artículos publicados en esta revista se distribuyen con la licencia: Articles published in th... more Los artículos publicados en esta revista se distribuyen con la licencia: Articles published in this journal are licensed with a: Creative Commons Attribution 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/ La revista no cobra tasas por el envío de trabajos, ni tampoco cuotas por la publicación de sus artículos. Original Artículo inglés Cardiovascular disease markers responses in male receiving improved-fat meat-products vary by initial LDL-cholesterol levels. La respuesta de marcadores de enfermedad cardiovascular al consumo de cárnicos con composición grasa mejorada depende de los niveles iniciales de LDL-colesterol.

Journal of Negative and No Positive Results: JONNPR, Sep 17, 2016

Journal of The American College of Nutrition, Jan 25, 2019

Objectives-Cardiovascular disease (CVD) risk is prevalent in high meat-product consumers. The eff... more Objectives-Cardiovascular disease (CVD) risk is prevalent in high meat-product consumers. The effect of consuming lipid-improved pâtés/frankfurters on plasma LDLcholesterol, thromboxane A2 (as TXB2), prostacyclin I2 (as 6-keto-PGF1), activated partial thromboplastin time, fibrinogen, antithrombin and insulin-resistance/sensitivity markers in volunteers at high CVD risk was studied. Subjects/methods-Eighteen male volunteers enrolled in a blind crossover-controlled study consumed improved products during three 4-wk periods: reduced fat (RF); n3enriched-RF (n-3RF), and normal fat (NF), separated by 4-wk washouts. Results-Fibrinogen and 6-keto-PG1 decreased (P<0.05) following the RF-period; LDL-cholesterol, TXB2 and 6-keto-PGF1 decreased (P<0.05) after the n-3RF-period, while LDL-cholesterol, fibrinogen, TXB2, insulin and HOMA-IR increased (at least P < 0.05) while QUICKI decreased (P<0.05) during the NF-period. The rate of changes of fibrinogen, TXB2 and 6-keto-PGF1 and HOMA-IR differ between groups (repeated measures test P<0.05). Fibrinogen, insulin, and HOMA-IR differed significantly (P<0.05) between RF and n-3RF period vs. NF period while that of TXB2 and 6-keto-PGF1 differed between n-3RF vs NF periods (P<0.05). Conclusions-The consumption of n-3RF meat-products followed by RF ones, partially reduced thrombogenesis, coagulation, and insulin-resistance markers. Thus, the inclusion of lipid-improved pâtés/frankfurters might be recommended into dietary strategies in at CVD-risk volunteers.

PubMed, Aug 1, 2015

Introduction: meat products have been recognized to be adequate matrix for incorporating function... more Introduction: meat products have been recognized to be adequate matrix for incorporating functional ingredients. The impact of meat products formulated by replacing animal fat with a combination of olive, linseed and fish oils on energy and nutrient intakes and anthropometric measurements were tested in a non-randomized-controlled- sequential study. Methods: eighteen male volunteers at high-CVD risk consumed weekly 200 g frankfurters and 250 g pâtés during three 4-wk periods (reduced fat (RF); n3-enriched- RF (n-3RF), and normal fat (NF)), separated by 4-wk washout. Energy and nutrient intakes, healthy eating index (HEI), and anthropometric changes were evaluated. Results: body fat mass rate-of-change and the waist/ hip ratio significantly differs (p = 0.018 and p = 0.031, respectively) between periods, decreasing body fat mass, waist circumference and waist/hip ratio in RF period and increasing body fat mass in NF one (all p = 0.05). Significant inverse correlations were observed between rate- of-change of BMI and ideal body weight with dietary carbohydrate/SFA ratio in n-3RF period (p = 0.003 and p = 0.006, respectively). Initial diets presented low HEIs (means < 60). Carbohydrate, fat and protein energy contribution was 40%, 41%, and 16%, respectively. More than 33% of volunteers did not initially cover 70% of several minerals and vitamins RDAs. Product consumption improved dietary Zn, Ca, retinol equivalent, folate and vitamin B12 contents in all periods, and ameliorated n-3 PUFA contents and n-6/n-3 PUFA ratio over the n-3RF period. Conclusion: improved-fat meat products appear as functional foods for overweight/obeses since their consumption improved selected body-fat markers, without affecting HEI, macronutrient and energy but their n-3 PUFA and n6/n3 ratio intakes.

Journal of Physiology and Biochemistry, Jul 4, 2016

High meat-product consumption has been related to cardiovascular disease (CVD). However, previous... more High meat-product consumption has been related to cardiovascular disease (CVD). However, previous results suggest the benefits of consuming improved fat meat products on lipoproteincholesterol and anthropometric measurements. Present study aims to assess the effect of consuming different Pâté and Frankfurter formulations on emergent CVD biomarkers in male volunteers at increased CVD risk. Eighteen male volunteers with at least two CVD risk factors were enrolled in a sequentially controlled study where different pork-products were tested: reduced-fat (RF), omega-3-enriched-RF (n-3RF), and normal-fat (NF). Pork-products were consumed during 4wk periods separated by 4wk washout. The cardiometabolic index (CI), oxidized low density lipoproteins (oxLDL), apolipoproteins (Apo) A1 and B, homocysteine (tHcys), arylesterase (AE), C-reactive Protein (CRP), tumor necrotic factor-alpha (TNF), lipoprotein (a) (Lp(a)) were tested and some other related ratios calculated. AE, oxLDL and Lp(a), AE/HDLc, LDLc/Apo B, AE/oxLDL rate of change were differently affected (P<0.01) by pork-products consumption. RF increased (P<0.05) AE, AE/HDLc and AE/oxLDL ratios and decreased TNF, tHcys; n-3RF increased (P<0.001) AE, AE/HDLc and AE/oxLDL ratios and decreased (P<0.05) Lp(a); while NF increased (P<0.05) oxLDL and Lp(a) levels. In conclusion RF and n-3RF products affected positively the level of some emergent CVD markers. The high regular consumption of NF-products should be limited as significantly increased Lp(a) and oxLDL values. The high variability in response observed for some markers suggests the need to perform more studies to identify targets for RF-and n-3RF-products.

Clinical Biochemistry, May 1, 2005

Objective: To assess the comparability of concentrations of retinol, aand g-tocopherols and indiv... more Objective: To assess the comparability of concentrations of retinol, aand g-tocopherols and individual carotenoids in serum and (Lihep) plasma over a wide range of concentrations. Material and methods: One hundred sixty-six pairs of samples (serum and lithium-heparin plasma) were analyzed by a qualitycontrolled HPLC method. Means and 95% confidence intervals, differences, interchangeability and the degree of agreement (Bland-Altman plot) were calculated. Results: Distribution of all analytes in the two matrices are comparable and interchangeable with minor quantitative adjustments. Within the range of concentrations assessed, the degree of agreement was high, although some differences were observed for minor components with greater analytical imprecision. Conclusions: The results indicate an acceptable degree of agreement using either of the two matrices for the analytes assessed except possibly for minor blood components. For retinol and a-tocopherol, the comparability and interchangeability of results below the cutoff points for inadequacy need further confirmation.

Food Chemistry, Dec 1, 2010

Meat Science, Dec 1, 2013

Osteoporosis International, Sep 20, 2007

Summary β-Cryptoxanthin displays a unique anabolic effect on bone calcification. In women with o... more Summary β-Cryptoxanthin displays a unique anabolic effect on bone calcification. In women with osteoporosis, serum β-cryptoxanthin and 25-OH-vitamin D3 showed a weak but significant correlation and exhibited a complementary seasonal distribution. The potential role of β-cryptoxanthin as a nutritional approach to improving bone health deserves further evaluation. Introduction Dietary intake and serum levels of β-cryptoxanthin have been inversely related to different bone