Yu Xue | The Chinese University of Hong Kong (original) (raw)

Papers by Yu Xue

The present invention relates to a kind of wood molding material and a method of manufacturing th... more The present invention relates to a kind of wood molding material and a method of manufacturing the same, in particular softwood material relates to a molding material and a method of manufacturing the same, belongs to the wood processing area. The invention has been achieved through the technical solution under. Sort of wood molding material production method comprises the steps below. (1) sawing process, (2) drying process, (3) planing procedures, (4) heating and compressing steps: advances a compact compression of the two surface layer of the sheet material bangagongpum of two heating platen temperature is 140 ~ 200 ℃ , (5) a pre-carbonization process: is carbonized under the conditions of the sheet material bangagongpum 200 ~ 225 ℃, (7) a cooling process, (8) sheet bangagongpum the thus pre-carbonized under the condition of 160 ~ 200 ℃, (6) carbonization process Moisture content control procedures. The invention is applicable to the manufacture of wood products, especially flooring and office furniture.

Ecs Journal of Solid State Science and Technology, 2013

Experimental Ba3.98−x(Si3O8)2: 0.02Eu 2+ , xTm 3+ (x = 0, 0.005, 0.01, 0.02, 0.03, 0.04) and Ba3.... more Experimental Ba3.98−x(Si3O8)2: 0.02Eu 2+ , xTm 3+ (x = 0, 0.005, 0.01, 0.02, 0.03, 0.04) and Ba3.98(Si3O8)2: 0.02Tm 3+ were synthesized by a conventional solid-state reaction method. The typical synthesizing procedure is shown as follows, BaCO3 (99%), SiO2 (99%), H3BO3 (99%), Eu2O3 (99.99%), and Tm2O3 (99.99%) were used as starting materials. H3BO3 was added as a flux and they were homogeneously mixed with ethanol in an agate mortar and ground thoroughly for 0.5 h according to the appropriate stoichiometric ratio, then sintered at 1300 ◦ C for 3 h under a reducing atmosphere (N2:H2 = 95:5) in a tube furnace. After annealing, the samples were cooled to room temperature in the furnace, and ground again into powder for subsequent use. The phases of samples were identified by X-ray powder diffraction (XRD) with Ni-filtered CuKα radiation (λ = 0.15406 nm) at a scanning step of 0.02 ◦ . The XRD data were collected in the range of 10 ◦ < 2θ < 65 ◦ by applying a D8 ADVANCE/Germany Bruker X-ray diffractometer. A Hitachi F-7000 fluorescence spectrophotometer was used to record PSL, PL, and photoluminescence excitation (PLE). TL curves were measured with a FJ-427A TL meter (Beijing Nuclear Instrument Factory). Prior to the measurements, powder samples were first pre-irradiated by UV light (365 nm) for about 10 min, then heated from room temperature to 400 ◦ C with a rate of 1 K/s. In order to investigate the mechanisms of the energy storing and recovering, the TL glow curves of the samples were measured with various treatments. Before measuring the PSL, the samples were pre-irradiated by 365 nm UV light for 10 min and then placed in dark for 10 min. An 808 nm laser diode is used as a stimulating source.

Phytoparasitica, 2010

Berberis thunbergii atropurpurea, also known as Red barberry, is a small ornamental shrub in the ... more Berberis thunbergii atropurpurea, also known as Red barberry, is a small ornamental shrub in the family Berberidaceae. In recent years, a phyllody symptom has been observed frequently, spreading in the shrubs in northwestern China. A phytoplasma 16S rDNA specific fragment was amplified by PCR from Berberis plants with the phyllody symptoms. DNA sequencing and restriction fragment length polymorphism analysis revealed

IEEE 2011 10th International Conference on Electronic Measurement & Instruments, 2011

A radar high resolution range profile (HRRP) contains rather detailed structural information of a... more A radar high resolution range profile (HRRP) contains rather detailed structural information of a target and provides us a more reliable tool for target recognition. Various feature extraction methods have been developed and applied to radar target recognition successfully. Usually, different features contain different discriminative information. So the recognition performance will be improved by utilizing different features extracted from HRRP

Diabetes Technology & Therapeutics, 2013

Background: Hyperglycemia is common and hard to control in surgical patients with diabetes. We re... more Background: Hyperglycemia is common and hard to control in surgical patients with diabetes. We retrospectively investigated short-term effects of continuous subcutaneous insulin infusion (CSII) in perioperative patients with diabetes. Patients and Methods: Perioperative patients with diabetes discharged between January 1, 2006 and January 1, 2012 were included. Glucose control and postoperative outcomes were compared between the patients using CSII or non-CSII insulin therapy. Results: We identified 108 pairs of patients matched by propensity and surgical category who were using CSII therapy (CSII group) or non-CSII insulin therapy (control group). The CSII group had significantly lower fasting glucose levels (on the first postoperative day, 9.06-3.09 mmol/L vs. 11.05-4.19 mmol/L; P = 0.003) and lower mean glucose levels (on the operation day, 9.93-2.65 mmol/L vs. 12.05-3.86 mmol/L; P = 0.001). The CSII group also had a lower incidence of fever (on the first postoperative day, 30.4% vs. 53.2%; P = 0.005). Furthermore, patients in the CSII group experienced significantly shorter postoperative intervals for suture removal (P = 0.02) and hospital discharge (P = 0.03). No significant difference in the total medical expenditure was observed between the two groups (P = 0.47). We also made a comparison between the 30 pairs of patients who were using CSII or multiple daily insulin injection therapy but observed no significant difference between these two therapies in glucose control or postoperative outcomes. Conclusions: Compared with non-CSII insulin therapy, even short-term implementation of CSII can improve the postoperative control of glucose, reduce the incidence of postoperative fever, and shorten the time for suture removal and discharge in surgical patients with diabetes.

2013 International Conference on Optoelectronics and Microelectronics (ICOM), 2013

ABSTRACT A hollow laser beam (HLB) is produced by a liquid-core optical fiber (LCOF) filled with ... more ABSTRACT A hollow laser beam (HLB) is produced by a liquid-core optical fiber (LCOF) filled with CS2. We investigate the dependences of the HLB quality on the laser coherence, the incident angle of the laser beam and the length of the LOCF, obtaining the conditions of high-quality HLBs. The Research results show that the lower laser coherence the better is the quality of HLBs. The quality of HLBs is also influenced by the incident angle of the laser beam and the length of the LCOF. We can achieve high-quality HLBs with longer LCOF when the incident angle of the laser beam is less than 10°. The generated HLBs with high quality can satisfy the needs of different applications.

SPIE Proceedings, 2014

ABSTRACT

Xenobiotica, 2007

There is an increasing use of herbal medicines worldwide, and the extracts from the root of Salvi... more There is an increasing use of herbal medicines worldwide, and the extracts from the root of Salvia miltiorrhiza are widely used in the treatment of angina and stroke. In this study, we investigated the mechanism for the intestinal absorption of tanshinone IIB (TSB), a major constituent of S. miltiorrhiza. The oral bioavailability of TSB was about 3% in rats with less proportional increase in its maximum plasma concentration (C max) and area under the plasma concentration-time curve (AUC) with increasing dosage. The time to C max (T max) was prolonged at higher oral dosage. In a single pass rat intestinal perfusion model, the permeability coefficients (P app) based on TSB disappearance from the lumen (P lumen) were 6.2-to 7.2-fold higher (p50.01) than those based on drug appearance in mesenteric venous blood (P blood). The uptake and efflux

Optical Materials, 2012

ABSTRACT

Materials Research Bulletin, 2013

Materials Letters, 2014

A large enhancement of photo-stimulated luminescence by co-doping Tm 3 þ /Dy 3 þ in α 0-Sr 2 SiO ... more A large enhancement of photo-stimulated luminescence by co-doping Tm 3 þ /Dy 3 þ in α 0-Sr 2 SiO 4 was observed, upon the infrared (IR) stimulation at 980 nm after pre-exposure with Ultraviolet (UV) light. More interestingly, the color of PSL changes from green to yellow with substituting Dy 3 þ with Tm 3 þ. The results indicate that co-doping of Tm 3 þ generates a large number of traps peaking at 400 K, which able to immobilized the carriers permanently at room temperature and is more sensitive to IR light than other traps. It induced the redistribution of trap centers, especially around the emission center Eu 2 which located at another inequivalent site.

Kidney International, 2007

Plasma creatinine may not reflect glomerular filtration rate (GFR) especially in the early stages... more Plasma creatinine may not reflect glomerular filtration rate (GFR) especially in the early stages of chronic kidney disease (CKD). Plasma cystatin C (cysC), however, has the potential to more accurately determine early GFR reduction. We sought to improve the creatinine-based GFR estimation by including cysC measurements. We derived a reference GFR from standard dual plasma sampling 99m Tc-DTPA clearance in a training cohort of 376 randomly selected adult Chinese patients with CKD. We compared reference values to estimated GFR and applied multiple regression models to one equation based solely on cysC, and to another combining plasma creatinine (Pcr) and cysC measurements of the training cohort. The results were validated by testing an additional 191 patients. The difference, precision, and accuracy of the two estimates were compared with the modified Modification of Diet in Renal Disease (MDRD) equation for Chinese patients, and another estimate combining cysC and modified MDRD calculations. The estimated GFR combining Pcr and cysC measurements more accurately matched the reference GFR at all stages of CKD than the other equations, particularly in patients with near-normal kidney function.

Journal of Luminescence, 2011

The effect of P 2 O 5 on infrared luminescence properties of bismuth-doped SiO 2-Al 2 O 3-CaO (SA... more The effect of P 2 O 5 on infrared luminescence properties of bismuth-doped SiO 2-Al 2 O 3-CaO (SAC) glass was investigated. Under excitation of 690 and 808 nm LD, two infrared emissions from bismuth ions central at 1100 and 1300 nm were observed, respectively. The addition of P 2 O 5 was not only found to lead to the increase of full width at half maximum (FWHM) of two infrared emissions, but also result in intensity variety of the infrared emissions. The intensity of the infrared emission located at 1300 nm is reduced by a factor of 2, while the luminescence at 1110 nm is increased by a factor of 5. We propose that the infrared emissions at 1100 and 1300 nm may originate from different valence Bi ion in glasses. Compared with emission at 1300 nm, the infrared emissions at 1100 nm is more possibly from the transition of lower valent Bi ion.

Journal of Applied Polymer Science, 2001

The use of renewable resources (mainly carbohydrates) in rigid polyurethane foam has been known t... more The use of renewable resources (mainly carbohydrates) in rigid polyurethane foam has been known to offer several advantages, such as increased strength, improved flame resistance, and enhanced biodegradability. Less attention has been directed to inexpensive protein-based materials, such as defatted soy flour. The objectives of this study were to develop water-blown rigid polyurethane foams, containing defatted soy flour, that have acceptable or improved physical properties which also lower the cost of the foam formulation and to compare the properties of developed foams extended with three kinds of commercial soy flour. Water-blown low-density rigid polyurethane foams were prepared with poly(ether polyol)s, polymeric isocyanates, defatted soy flour, water, a catalyst mixture, and a surfactant. Soy flour and the initial water content were varied from 0 to 40% and from 4.5 to 5.5% of the poly(ether polyol) content, respectively. A standard laboratory mixing procedure was followed for making foams using a high-speed industrial mixer. After mixing, the mixture was poured into boxes and allowed to rise at ambient conditions. Foams were removed from boxes after 1 h and cured at room temperature for 24 h before measurement of the thermal conductivity and for 1 week before other property tests. Foam properties were determined according to ASTM procedures. Measurement of the physical properties (compressive strength, modulus, thermal conductivity, and dimensional stability under thermal and humid aging) of these foams showed that the addition of 10-20% of three kinds of soy flour imparted water-blown rigid polyurethane foams with similar or improved strength, modulus, insulation, and dimensional stability.

Journal of Applied Polymer Science, 2001

Glass transition temperatures of water-blown rigid polyurethane foams at three levels of initial ... more Glass transition temperatures of water-blown rigid polyurethane foams at three levels of initial water content, 4.5-5.5%, and five levels of soy flour, 0-40%, were determined by dynamic-mechanical instrumentation at the temperature range of 50-280°C and the frequencies from 0.1 to 20 Hz. The results showed that both the addition of soy flour in the rigid polyurethane foam system and increasing initial water content contributed to a higher glass transition temperature. Moreover, increasing the percentage of the soy flour in the rigid polyurethane foam system led to higher compressive strength and broader master curves for the imaginary part of the elastic modulus. The KWW function fitted the master curve better than the HN and CD functions.

International Journal of Bifurcation and Chaos, 2009

In this paper, the stochastic driving and coupling method to effectively suppress the turbulence ... more In this paper, the stochastic driving and coupling method to effectively suppress the turbulence and spiral waves is proposed. It is confirmed that the drive system ensures the response achieves complete synchronization via the computation of the Pearson's coefficient γ. The minimum time units of achieving complete synchronization N versus the coupling proportion P takes on the power-law N ~ P-k.

IEEE Photonics Technology Letters, 2005

We propose and demonstrate a novel room-temperature multiwavelength erbium-doped fiber laser (EDF... more We propose and demonstrate a novel room-temperature multiwavelength erbium-doped fiber laser (EDFL) with a 0.8-nm wavelength spacing based on four-wave mixing (FWM) in a length of high-nonlinear photonic crystal fiber and sampled-fiber Bragg grating. The FWM processes suppress the wavelength competition of the EDFL and increase the number of lasing wavelength. By adjusting the FWM efficiency, the number of the concurrent lasing wavelengths can be changed, and the peak power differences among the main oscillation wavelengths are less than 2.0 dB.

Drug Development and Industrial Pharmacy, 2010

Background: Considering the chronic and repeated nature of salmon calcitonin (sCT) therapy, the o... more Background: Considering the chronic and repeated nature of salmon calcitonin (sCT) therapy, the oral route is a preferred route of administration. But, the oral bioavailability of sCT is very low due to enzymatic degradation and poor permeation across intestinal epithelial cells. It was the aim of this study to investigate the pharmacodynamic (PD), pharmacokinetic (PK), and mucosal injury characteristic of sCT oral delivery system. Method: In this study, PD experiments were performed to find a suitable releasing region of sCT, an effect absorption enhancer, and an optimal mass ratio of sCT/enhancer. In addition, the PK experiments were designed to validate the absorption enhancement of this oral delivery system. Histopathological evaluations on the intestinal mucosa were carried out to assess any potential toxicity of the absorption enhancer. Results: Through the PD research, we determined that oral sCT enteric-coated capsules containing sCT and citric acid (CA) with a ratio of 1:20 may be an adaptable delivery. PK study further proved that the oral absorption of sCT was enhanced from this delivery system. Finally, no damage on intestinal mucosa was observed when rats received the delivery system containing CA for up to 7 days. Conclusion: These results suggested that enteric-coated capsules with a certain amount of CA might give enhanced oral delivery of peptide drugs like sCT.

Current Drug Metabolism, 2007

The extracts from the roots of Salvia miltiorrhiza Bunge (Danshen) are widely and traditionally u... more The extracts from the roots of Salvia miltiorrhiza Bunge (Danshen) are widely and traditionally used in the treatment of angina pectoris, acute myocardial infarct, hyperlipidemia and stroke in China and other Asian countries. In this study, we have investigated the role of P-glycoprotein (P-gp) in the intestinal absorption of tanshinone IIA (TSA), a major active constituent of Danshen, using several in vitro and in vivo models. The oral bioavailability of TSA was about 2.9 3.4% in rats, with non-linear pharmacokinetics when its dosage increased. In a single pass rat intestinal perfusion model, the permeability coefficients (Papp) based on TSA disappearance from the luminal perfusates (Plumen) were 6.2-to 7.2-fold higher (P < 0.01) than those based on drug appearance in mesenteric venous blood (Pblood). The Pblood, but not Plumen, was significantly increased when co-perfused with verapamil, or quinidine (both P-gp inhibitors). The uptake and efflux of TSA in confluent Caco-2 cells were significantly altered in the presence of verapamil, quinidine, MK-571, or probenecid. The transport of TSA across Caco-2 monolayers was pH-, temperature-and ATP-dependent. Furthermore, the transport from the apical (AP) to basolateral (BL) side of the Caco-2 monolayers was 3.3-to 8.5-fold lower than that from the BL to AP side, but such a polarized transport was attenuated by co-incubated verapamil or quinidine. A polarized transport was also observed in the control MDCKII cells and more apparent in MDR1-MDCKII monolayers, with the Papp values of TSA in the BL-AP direction being 7-to 9-fold higher in MDR1-MDCKII monolayers than those in the control MDCKII cells. Moreover, TSA significantly inhibited P-gp-mediated transport of digoxin in P-gp-overexpressing membrane vesicles with an IC50 of 2.6 M, but stimulated vanadate-sensitive P-gp ATPase activity with estimated Km and Vmax values of 10.70 ± 0.69 M and 67.65 ± 1.31 nmol/min/mg protein, respectively. TSA was extensively metabolized to tanshinone IIB (TSB), and two other oxidative metabolites in rat liver microsomes, but the formation rate of TSB in rat intestinal microsomes was only about 1/10 of that in liver microsomes. These findings indicate that TSA is a substrate and reversing agent for P-gp; and P-gp-mediated efflux of TSA into the gut lumen and the first-pass metabolism contribute to the low oral bioavailability. Further studies are needed to explore the role of other drug transporters and first-pass metabolism in the low bioavailability of TSA.

Clinical and Experimental Pharmacology and Physiology, 2013

1. The aim of the present study was to compare the performance of HbA1c and fasting plasma glucos... more 1. The aim of the present study was to compare the performance of HbA1c and fasting plasma glucose (FPG) in identifying dysglycaemic status among Chinese participants. 2. Fasting plasma glucose and HbA1c were measured in 2318 subjects with at least one risk factor for diabetes but without being previously diagnosed with diabetes. 3. Using HbA1c to diagnose diabetes resulted in the same classification as FPG for 90.5% of the study participants, with 21.0% (n = 487) classified as having diabetes by both FPG and HbA1c and 69.5% (n = 1610) classified as not having diabetes by both FPG and HbA1c. The kappa (j) coefficient of the FPG criterion with the HbA1c criterion for diabetes was 0.75 (95% confidence interval (CI) 0.72-0.78). The overlap index regarding diabetes diagnosed by FPG or HbA1c was 68.8%. Of 1610 subjects with FPG < 126 mg/dL and HbA1c < 6.5%, 220 (13.7%) had FPG ≥ 100 mg/dL and HbA1c < 5.7%, whereas 277 (17.2%) had FPG < 100 mg/dL and HbA1c ≥ 5.7%. The j coefficient of the FPG criterion with the HbA1c criterion for prediabetes was 0.30 (95% CI 0.25-0.35). The overlap index between subjects diagnosed as having prediabetes by FPG of 100-125 mg/dL (impaired fasting glucose (IFG)) or HbA1c of 5.7-6.4% (increased HbA1c (IGH)) was 35.9%. 4. The HbA1c criterion demonstrates reasonable concordance with the FPG criterion for diabetes. Hence, HbA1c and FPG can be used for the diagnosis of diabetes. However, the IGH shows limited overlap with IFG for prediabetes. Introduction of the IGH criterion in addition to IFG for the screening of prediabetes could lead to the identification of more people with this condition.

The present invention relates to a kind of wood molding material and a method of manufacturing th... more The present invention relates to a kind of wood molding material and a method of manufacturing the same, in particular softwood material relates to a molding material and a method of manufacturing the same, belongs to the wood processing area. The invention has been achieved through the technical solution under. Sort of wood molding material production method comprises the steps below. (1) sawing process, (2) drying process, (3) planing procedures, (4) heating and compressing steps: advances a compact compression of the two surface layer of the sheet material bangagongpum of two heating platen temperature is 140 ~ 200 ℃ , (5) a pre-carbonization process: is carbonized under the conditions of the sheet material bangagongpum 200 ~ 225 ℃, (7) a cooling process, (8) sheet bangagongpum the thus pre-carbonized under the condition of 160 ~ 200 ℃, (6) carbonization process Moisture content control procedures. The invention is applicable to the manufacture of wood products, especially flooring and office furniture.

Ecs Journal of Solid State Science and Technology, 2013

Experimental Ba3.98−x(Si3O8)2: 0.02Eu 2+ , xTm 3+ (x = 0, 0.005, 0.01, 0.02, 0.03, 0.04) and Ba3.... more Experimental Ba3.98−x(Si3O8)2: 0.02Eu 2+ , xTm 3+ (x = 0, 0.005, 0.01, 0.02, 0.03, 0.04) and Ba3.98(Si3O8)2: 0.02Tm 3+ were synthesized by a conventional solid-state reaction method. The typical synthesizing procedure is shown as follows, BaCO3 (99%), SiO2 (99%), H3BO3 (99%), Eu2O3 (99.99%), and Tm2O3 (99.99%) were used as starting materials. H3BO3 was added as a flux and they were homogeneously mixed with ethanol in an agate mortar and ground thoroughly for 0.5 h according to the appropriate stoichiometric ratio, then sintered at 1300 ◦ C for 3 h under a reducing atmosphere (N2:H2 = 95:5) in a tube furnace. After annealing, the samples were cooled to room temperature in the furnace, and ground again into powder for subsequent use. The phases of samples were identified by X-ray powder diffraction (XRD) with Ni-filtered CuKα radiation (λ = 0.15406 nm) at a scanning step of 0.02 ◦ . The XRD data were collected in the range of 10 ◦ < 2θ < 65 ◦ by applying a D8 ADVANCE/Germany Bruker X-ray diffractometer. A Hitachi F-7000 fluorescence spectrophotometer was used to record PSL, PL, and photoluminescence excitation (PLE). TL curves were measured with a FJ-427A TL meter (Beijing Nuclear Instrument Factory). Prior to the measurements, powder samples were first pre-irradiated by UV light (365 nm) for about 10 min, then heated from room temperature to 400 ◦ C with a rate of 1 K/s. In order to investigate the mechanisms of the energy storing and recovering, the TL glow curves of the samples were measured with various treatments. Before measuring the PSL, the samples were pre-irradiated by 365 nm UV light for 10 min and then placed in dark for 10 min. An 808 nm laser diode is used as a stimulating source.

Phytoparasitica, 2010

Berberis thunbergii atropurpurea, also known as Red barberry, is a small ornamental shrub in the ... more Berberis thunbergii atropurpurea, also known as Red barberry, is a small ornamental shrub in the family Berberidaceae. In recent years, a phyllody symptom has been observed frequently, spreading in the shrubs in northwestern China. A phytoplasma 16S rDNA specific fragment was amplified by PCR from Berberis plants with the phyllody symptoms. DNA sequencing and restriction fragment length polymorphism analysis revealed

IEEE 2011 10th International Conference on Electronic Measurement & Instruments, 2011

A radar high resolution range profile (HRRP) contains rather detailed structural information of a... more A radar high resolution range profile (HRRP) contains rather detailed structural information of a target and provides us a more reliable tool for target recognition. Various feature extraction methods have been developed and applied to radar target recognition successfully. Usually, different features contain different discriminative information. So the recognition performance will be improved by utilizing different features extracted from HRRP

Diabetes Technology & Therapeutics, 2013

Background: Hyperglycemia is common and hard to control in surgical patients with diabetes. We re... more Background: Hyperglycemia is common and hard to control in surgical patients with diabetes. We retrospectively investigated short-term effects of continuous subcutaneous insulin infusion (CSII) in perioperative patients with diabetes. Patients and Methods: Perioperative patients with diabetes discharged between January 1, 2006 and January 1, 2012 were included. Glucose control and postoperative outcomes were compared between the patients using CSII or non-CSII insulin therapy. Results: We identified 108 pairs of patients matched by propensity and surgical category who were using CSII therapy (CSII group) or non-CSII insulin therapy (control group). The CSII group had significantly lower fasting glucose levels (on the first postoperative day, 9.06-3.09 mmol/L vs. 11.05-4.19 mmol/L; P = 0.003) and lower mean glucose levels (on the operation day, 9.93-2.65 mmol/L vs. 12.05-3.86 mmol/L; P = 0.001). The CSII group also had a lower incidence of fever (on the first postoperative day, 30.4% vs. 53.2%; P = 0.005). Furthermore, patients in the CSII group experienced significantly shorter postoperative intervals for suture removal (P = 0.02) and hospital discharge (P = 0.03). No significant difference in the total medical expenditure was observed between the two groups (P = 0.47). We also made a comparison between the 30 pairs of patients who were using CSII or multiple daily insulin injection therapy but observed no significant difference between these two therapies in glucose control or postoperative outcomes. Conclusions: Compared with non-CSII insulin therapy, even short-term implementation of CSII can improve the postoperative control of glucose, reduce the incidence of postoperative fever, and shorten the time for suture removal and discharge in surgical patients with diabetes.

2013 International Conference on Optoelectronics and Microelectronics (ICOM), 2013

ABSTRACT A hollow laser beam (HLB) is produced by a liquid-core optical fiber (LCOF) filled with ... more ABSTRACT A hollow laser beam (HLB) is produced by a liquid-core optical fiber (LCOF) filled with CS2. We investigate the dependences of the HLB quality on the laser coherence, the incident angle of the laser beam and the length of the LOCF, obtaining the conditions of high-quality HLBs. The Research results show that the lower laser coherence the better is the quality of HLBs. The quality of HLBs is also influenced by the incident angle of the laser beam and the length of the LCOF. We can achieve high-quality HLBs with longer LCOF when the incident angle of the laser beam is less than 10°. The generated HLBs with high quality can satisfy the needs of different applications.

SPIE Proceedings, 2014

ABSTRACT

Xenobiotica, 2007

There is an increasing use of herbal medicines worldwide, and the extracts from the root of Salvi... more There is an increasing use of herbal medicines worldwide, and the extracts from the root of Salvia miltiorrhiza are widely used in the treatment of angina and stroke. In this study, we investigated the mechanism for the intestinal absorption of tanshinone IIB (TSB), a major constituent of S. miltiorrhiza. The oral bioavailability of TSB was about 3% in rats with less proportional increase in its maximum plasma concentration (C max) and area under the plasma concentration-time curve (AUC) with increasing dosage. The time to C max (T max) was prolonged at higher oral dosage. In a single pass rat intestinal perfusion model, the permeability coefficients (P app) based on TSB disappearance from the lumen (P lumen) were 6.2-to 7.2-fold higher (p50.01) than those based on drug appearance in mesenteric venous blood (P blood). The uptake and efflux

Optical Materials, 2012

ABSTRACT

Materials Research Bulletin, 2013

Materials Letters, 2014

A large enhancement of photo-stimulated luminescence by co-doping Tm 3 þ /Dy 3 þ in α 0-Sr 2 SiO ... more A large enhancement of photo-stimulated luminescence by co-doping Tm 3 þ /Dy 3 þ in α 0-Sr 2 SiO 4 was observed, upon the infrared (IR) stimulation at 980 nm after pre-exposure with Ultraviolet (UV) light. More interestingly, the color of PSL changes from green to yellow with substituting Dy 3 þ with Tm 3 þ. The results indicate that co-doping of Tm 3 þ generates a large number of traps peaking at 400 K, which able to immobilized the carriers permanently at room temperature and is more sensitive to IR light than other traps. It induced the redistribution of trap centers, especially around the emission center Eu 2 which located at another inequivalent site.

Kidney International, 2007

Plasma creatinine may not reflect glomerular filtration rate (GFR) especially in the early stages... more Plasma creatinine may not reflect glomerular filtration rate (GFR) especially in the early stages of chronic kidney disease (CKD). Plasma cystatin C (cysC), however, has the potential to more accurately determine early GFR reduction. We sought to improve the creatinine-based GFR estimation by including cysC measurements. We derived a reference GFR from standard dual plasma sampling 99m Tc-DTPA clearance in a training cohort of 376 randomly selected adult Chinese patients with CKD. We compared reference values to estimated GFR and applied multiple regression models to one equation based solely on cysC, and to another combining plasma creatinine (Pcr) and cysC measurements of the training cohort. The results were validated by testing an additional 191 patients. The difference, precision, and accuracy of the two estimates were compared with the modified Modification of Diet in Renal Disease (MDRD) equation for Chinese patients, and another estimate combining cysC and modified MDRD calculations. The estimated GFR combining Pcr and cysC measurements more accurately matched the reference GFR at all stages of CKD than the other equations, particularly in patients with near-normal kidney function.

Journal of Luminescence, 2011

The effect of P 2 O 5 on infrared luminescence properties of bismuth-doped SiO 2-Al 2 O 3-CaO (SA... more The effect of P 2 O 5 on infrared luminescence properties of bismuth-doped SiO 2-Al 2 O 3-CaO (SAC) glass was investigated. Under excitation of 690 and 808 nm LD, two infrared emissions from bismuth ions central at 1100 and 1300 nm were observed, respectively. The addition of P 2 O 5 was not only found to lead to the increase of full width at half maximum (FWHM) of two infrared emissions, but also result in intensity variety of the infrared emissions. The intensity of the infrared emission located at 1300 nm is reduced by a factor of 2, while the luminescence at 1110 nm is increased by a factor of 5. We propose that the infrared emissions at 1100 and 1300 nm may originate from different valence Bi ion in glasses. Compared with emission at 1300 nm, the infrared emissions at 1100 nm is more possibly from the transition of lower valent Bi ion.

Journal of Applied Polymer Science, 2001

The use of renewable resources (mainly carbohydrates) in rigid polyurethane foam has been known t... more The use of renewable resources (mainly carbohydrates) in rigid polyurethane foam has been known to offer several advantages, such as increased strength, improved flame resistance, and enhanced biodegradability. Less attention has been directed to inexpensive protein-based materials, such as defatted soy flour. The objectives of this study were to develop water-blown rigid polyurethane foams, containing defatted soy flour, that have acceptable or improved physical properties which also lower the cost of the foam formulation and to compare the properties of developed foams extended with three kinds of commercial soy flour. Water-blown low-density rigid polyurethane foams were prepared with poly(ether polyol)s, polymeric isocyanates, defatted soy flour, water, a catalyst mixture, and a surfactant. Soy flour and the initial water content were varied from 0 to 40% and from 4.5 to 5.5% of the poly(ether polyol) content, respectively. A standard laboratory mixing procedure was followed for making foams using a high-speed industrial mixer. After mixing, the mixture was poured into boxes and allowed to rise at ambient conditions. Foams were removed from boxes after 1 h and cured at room temperature for 24 h before measurement of the thermal conductivity and for 1 week before other property tests. Foam properties were determined according to ASTM procedures. Measurement of the physical properties (compressive strength, modulus, thermal conductivity, and dimensional stability under thermal and humid aging) of these foams showed that the addition of 10-20% of three kinds of soy flour imparted water-blown rigid polyurethane foams with similar or improved strength, modulus, insulation, and dimensional stability.

Journal of Applied Polymer Science, 2001

Glass transition temperatures of water-blown rigid polyurethane foams at three levels of initial ... more Glass transition temperatures of water-blown rigid polyurethane foams at three levels of initial water content, 4.5-5.5%, and five levels of soy flour, 0-40%, were determined by dynamic-mechanical instrumentation at the temperature range of 50-280°C and the frequencies from 0.1 to 20 Hz. The results showed that both the addition of soy flour in the rigid polyurethane foam system and increasing initial water content contributed to a higher glass transition temperature. Moreover, increasing the percentage of the soy flour in the rigid polyurethane foam system led to higher compressive strength and broader master curves for the imaginary part of the elastic modulus. The KWW function fitted the master curve better than the HN and CD functions.

International Journal of Bifurcation and Chaos, 2009

In this paper, the stochastic driving and coupling method to effectively suppress the turbulence ... more In this paper, the stochastic driving and coupling method to effectively suppress the turbulence and spiral waves is proposed. It is confirmed that the drive system ensures the response achieves complete synchronization via the computation of the Pearson's coefficient γ. The minimum time units of achieving complete synchronization N versus the coupling proportion P takes on the power-law N ~ P-k.

IEEE Photonics Technology Letters, 2005

We propose and demonstrate a novel room-temperature multiwavelength erbium-doped fiber laser (EDF... more We propose and demonstrate a novel room-temperature multiwavelength erbium-doped fiber laser (EDFL) with a 0.8-nm wavelength spacing based on four-wave mixing (FWM) in a length of high-nonlinear photonic crystal fiber and sampled-fiber Bragg grating. The FWM processes suppress the wavelength competition of the EDFL and increase the number of lasing wavelength. By adjusting the FWM efficiency, the number of the concurrent lasing wavelengths can be changed, and the peak power differences among the main oscillation wavelengths are less than 2.0 dB.

Drug Development and Industrial Pharmacy, 2010

Background: Considering the chronic and repeated nature of salmon calcitonin (sCT) therapy, the o... more Background: Considering the chronic and repeated nature of salmon calcitonin (sCT) therapy, the oral route is a preferred route of administration. But, the oral bioavailability of sCT is very low due to enzymatic degradation and poor permeation across intestinal epithelial cells. It was the aim of this study to investigate the pharmacodynamic (PD), pharmacokinetic (PK), and mucosal injury characteristic of sCT oral delivery system. Method: In this study, PD experiments were performed to find a suitable releasing region of sCT, an effect absorption enhancer, and an optimal mass ratio of sCT/enhancer. In addition, the PK experiments were designed to validate the absorption enhancement of this oral delivery system. Histopathological evaluations on the intestinal mucosa were carried out to assess any potential toxicity of the absorption enhancer. Results: Through the PD research, we determined that oral sCT enteric-coated capsules containing sCT and citric acid (CA) with a ratio of 1:20 may be an adaptable delivery. PK study further proved that the oral absorption of sCT was enhanced from this delivery system. Finally, no damage on intestinal mucosa was observed when rats received the delivery system containing CA for up to 7 days. Conclusion: These results suggested that enteric-coated capsules with a certain amount of CA might give enhanced oral delivery of peptide drugs like sCT.

Current Drug Metabolism, 2007

The extracts from the roots of Salvia miltiorrhiza Bunge (Danshen) are widely and traditionally u... more The extracts from the roots of Salvia miltiorrhiza Bunge (Danshen) are widely and traditionally used in the treatment of angina pectoris, acute myocardial infarct, hyperlipidemia and stroke in China and other Asian countries. In this study, we have investigated the role of P-glycoprotein (P-gp) in the intestinal absorption of tanshinone IIA (TSA), a major active constituent of Danshen, using several in vitro and in vivo models. The oral bioavailability of TSA was about 2.9 3.4% in rats, with non-linear pharmacokinetics when its dosage increased. In a single pass rat intestinal perfusion model, the permeability coefficients (Papp) based on TSA disappearance from the luminal perfusates (Plumen) were 6.2-to 7.2-fold higher (P < 0.01) than those based on drug appearance in mesenteric venous blood (Pblood). The Pblood, but not Plumen, was significantly increased when co-perfused with verapamil, or quinidine (both P-gp inhibitors). The uptake and efflux of TSA in confluent Caco-2 cells were significantly altered in the presence of verapamil, quinidine, MK-571, or probenecid. The transport of TSA across Caco-2 monolayers was pH-, temperature-and ATP-dependent. Furthermore, the transport from the apical (AP) to basolateral (BL) side of the Caco-2 monolayers was 3.3-to 8.5-fold lower than that from the BL to AP side, but such a polarized transport was attenuated by co-incubated verapamil or quinidine. A polarized transport was also observed in the control MDCKII cells and more apparent in MDR1-MDCKII monolayers, with the Papp values of TSA in the BL-AP direction being 7-to 9-fold higher in MDR1-MDCKII monolayers than those in the control MDCKII cells. Moreover, TSA significantly inhibited P-gp-mediated transport of digoxin in P-gp-overexpressing membrane vesicles with an IC50 of 2.6 M, but stimulated vanadate-sensitive P-gp ATPase activity with estimated Km and Vmax values of 10.70 ± 0.69 M and 67.65 ± 1.31 nmol/min/mg protein, respectively. TSA was extensively metabolized to tanshinone IIB (TSB), and two other oxidative metabolites in rat liver microsomes, but the formation rate of TSB in rat intestinal microsomes was only about 1/10 of that in liver microsomes. These findings indicate that TSA is a substrate and reversing agent for P-gp; and P-gp-mediated efflux of TSA into the gut lumen and the first-pass metabolism contribute to the low oral bioavailability. Further studies are needed to explore the role of other drug transporters and first-pass metabolism in the low bioavailability of TSA.

Clinical and Experimental Pharmacology and Physiology, 2013

1. The aim of the present study was to compare the performance of HbA1c and fasting plasma glucos... more 1. The aim of the present study was to compare the performance of HbA1c and fasting plasma glucose (FPG) in identifying dysglycaemic status among Chinese participants. 2. Fasting plasma glucose and HbA1c were measured in 2318 subjects with at least one risk factor for diabetes but without being previously diagnosed with diabetes. 3. Using HbA1c to diagnose diabetes resulted in the same classification as FPG for 90.5% of the study participants, with 21.0% (n = 487) classified as having diabetes by both FPG and HbA1c and 69.5% (n = 1610) classified as not having diabetes by both FPG and HbA1c. The kappa (j) coefficient of the FPG criterion with the HbA1c criterion for diabetes was 0.75 (95% confidence interval (CI) 0.72-0.78). The overlap index regarding diabetes diagnosed by FPG or HbA1c was 68.8%. Of 1610 subjects with FPG < 126 mg/dL and HbA1c < 6.5%, 220 (13.7%) had FPG ≥ 100 mg/dL and HbA1c < 5.7%, whereas 277 (17.2%) had FPG < 100 mg/dL and HbA1c ≥ 5.7%. The j coefficient of the FPG criterion with the HbA1c criterion for prediabetes was 0.30 (95% CI 0.25-0.35). The overlap index between subjects diagnosed as having prediabetes by FPG of 100-125 mg/dL (impaired fasting glucose (IFG)) or HbA1c of 5.7-6.4% (increased HbA1c (IGH)) was 35.9%. 4. The HbA1c criterion demonstrates reasonable concordance with the FPG criterion for diabetes. Hence, HbA1c and FPG can be used for the diagnosis of diabetes. However, the IGH shows limited overlap with IFG for prediabetes. Introduction of the IGH criterion in addition to IFG for the screening of prediabetes could lead to the identification of more people with this condition.