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Research paper thumbnail of Health Services Management Centre (HSMC) University of Birmingham

Work in progress not for citation without authors permission ... 14th Annual Conference of the In... more Work in progress not for citation without authors permission ... 14th Annual Conference of the International Research ... Work in progress not for citation without authors permission ... National Health Service (NHS) commissioning in England Within the UK, successive waves of ...

Research paper thumbnail of Disinvestment in health—the challenges facing general practitioner (GP) commissioners

The economic downturn is placing increasing pressure on the financing of health care. For many he... more The economic downturn is placing increasing pressure on the financing of health care. For many health care providers, this means difficult decisions need to be made over what will and will not be funded. The NHS has not typically been good at decommissioning and ...

Research paper thumbnail of Clinical Microsystems: An Evaluation

… Centre, University of …, Jan 1, 2007

Research paper thumbnail of Clinical microsystems and the NHS: A sustainable method for improvement?

Journal of Health Organisation and Management, Jan 1, 2009

Research paper thumbnail of Modelling in the economic evaluation of health care: selecting the appropriate approach

Journal of Health Services Research & Policy, 2004

To provide an overview of alternative approaches to modelling in economic evaluation, and to high... more To provide an overview of alternative approaches to modelling in economic evaluation, and to highlight situations where each of the alternative modelling techniques should be employed. A review of the available approaches to modelling in the economic evaluation of health care interventions with a leading discussion of examples of published studies leading to guidance in the selection of an appropriate approach in different circumstances. The main approaches to modelling used in economic evaluations in health care are decision trees, Markov models and individual sampling models. These methods assume independence of individuals within the model. Where interaction between individuals is important, other methods such as discrete-event simulation or system dynamics are preferable. The paper highlights the crucial question to be answered when selecting the approach to modelling: can the individuals being simulated in the model be regarded as independent? This issue is very commonly not recognised by analysts but is fundamental to the appropriate application of modelling in economic evaluation.

Research paper thumbnail of Healthcare and patient costs of a proactive chlamydia screening programme: the Chlamydia Screening Studies project

Sexually Transmitted Infections, 2007

Background and objective: Most economic evaluations of chlamydia screening do not include costs i... more Background and objective: Most economic evaluations of chlamydia screening do not include costs incurred by patients. The objective of this study was to estimate both the health service and private costs of patients who participated in proactive chlamydia screening, using mailed home-collected specimens as part of the Chlamydia Screening Studies project. Methods: Data were collected on the administrative costs of the screening study, laboratory time and motion studies and patient-cost questionnaire surveys were conducted. The cost for each screening invitation and for each accepted offer was estimated. One-way sensitivity analysis was conducted to explore the effects of variations in patient costs and the number of patients accepting the screening offer. Results: The time and costs of processing urine specimens and vulvo-vaginal swabs from women using two nucleic acid amplification tests were similar. The total cost per screening invitation was £20.37 (95% CI £18.94 to 24.83). This included the National Health Service cost per individual screening invitation £13.55 (95% CI £13.15 to 14.33) and average patient costs of £6.82 (95% CI £5.48 to 10.22). Administrative costs accounted for 50% of the overall cost. Conclusions: The cost of proactive chlamydia screening is comparable to those of opportunistic screening. Results from this study, which is the first to collect private patient costs associated with a chlamydia screening programme, could be used to inform future policy recommendations and provide unique primary cost data for economic evaluations.

Research paper thumbnail of Cost effectiveness of home based population screening for Chlamydia trachomatis in the UK: economic evaluation of chlamydia screening studies (ClaSS) project

British Medical Journal, 2007

Objective To investigate the cost effectiveness of screening for Chlamydia trachomatis compared w... more Objective To investigate the cost effectiveness of screening for Chlamydia trachomatis compared with a policy of no organised screening in the United Kingdom. Design Economic evaluation using a transmission dynamic mathematical model. Setting Central and southwest England. Participants Hypothetical population of 50 000 men and women, in which all those aged 16-24 years were invited to be screened each year. Main outcome measures Cost effectiveness based on major outcomes averted, defined as pelvic inflammatory disease, ectopic pregnancy, infertility, or neonatal complications. Results The incremental cost per major outcome averted for a programme of screening women only (assuming eight years of screening) was £22 300 (€33 000; $45 000) compared with no organised screening. For a programme screening both men and women, the incremental cost effectiveness ratio was approximately £28 900. Pelvic inflammatory disease leading to hospital admission was the most frequently averted major outcome. The model was highly sensitive to the incidence of major outcomes and to uptake of screening. When both were increased the cost effectiveness ratio fell to £6200 per major outcome averted for screening women only. Conclusions Proactive register based screening for chlamydia is not cost effective if the uptake of screening and incidence of complications are based on contemporary empirical studies, which show lower rates than commonly assumed. These data are relevant to discussions about the cost effectiveness of the opportunistic model of chlamydia screening being introduced in England.

Research paper thumbnail of Health Services Management Centre (HSMC) University of Birmingham

Work in progress not for citation without authors permission ... 14th Annual Conference of the In... more Work in progress not for citation without authors permission ... 14th Annual Conference of the International Research ... Work in progress not for citation without authors permission ... National Health Service (NHS) commissioning in England Within the UK, successive waves of ...

Research paper thumbnail of Disinvestment in health—the challenges facing general practitioner (GP) commissioners

The economic downturn is placing increasing pressure on the financing of health care. For many he... more The economic downturn is placing increasing pressure on the financing of health care. For many health care providers, this means difficult decisions need to be made over what will and will not be funded. The NHS has not typically been good at decommissioning and ...

Research paper thumbnail of Clinical Microsystems: An Evaluation

… Centre, University of …, Jan 1, 2007

Research paper thumbnail of Clinical microsystems and the NHS: A sustainable method for improvement?

Journal of Health Organisation and Management, Jan 1, 2009

Research paper thumbnail of Modelling in the economic evaluation of health care: selecting the appropriate approach

Journal of Health Services Research & Policy, 2004

To provide an overview of alternative approaches to modelling in economic evaluation, and to high... more To provide an overview of alternative approaches to modelling in economic evaluation, and to highlight situations where each of the alternative modelling techniques should be employed. A review of the available approaches to modelling in the economic evaluation of health care interventions with a leading discussion of examples of published studies leading to guidance in the selection of an appropriate approach in different circumstances. The main approaches to modelling used in economic evaluations in health care are decision trees, Markov models and individual sampling models. These methods assume independence of individuals within the model. Where interaction between individuals is important, other methods such as discrete-event simulation or system dynamics are preferable. The paper highlights the crucial question to be answered when selecting the approach to modelling: can the individuals being simulated in the model be regarded as independent? This issue is very commonly not recognised by analysts but is fundamental to the appropriate application of modelling in economic evaluation.

Research paper thumbnail of Healthcare and patient costs of a proactive chlamydia screening programme: the Chlamydia Screening Studies project

Sexually Transmitted Infections, 2007

Background and objective: Most economic evaluations of chlamydia screening do not include costs i... more Background and objective: Most economic evaluations of chlamydia screening do not include costs incurred by patients. The objective of this study was to estimate both the health service and private costs of patients who participated in proactive chlamydia screening, using mailed home-collected specimens as part of the Chlamydia Screening Studies project. Methods: Data were collected on the administrative costs of the screening study, laboratory time and motion studies and patient-cost questionnaire surveys were conducted. The cost for each screening invitation and for each accepted offer was estimated. One-way sensitivity analysis was conducted to explore the effects of variations in patient costs and the number of patients accepting the screening offer. Results: The time and costs of processing urine specimens and vulvo-vaginal swabs from women using two nucleic acid amplification tests were similar. The total cost per screening invitation was £20.37 (95% CI £18.94 to 24.83). This included the National Health Service cost per individual screening invitation £13.55 (95% CI £13.15 to 14.33) and average patient costs of £6.82 (95% CI £5.48 to 10.22). Administrative costs accounted for 50% of the overall cost. Conclusions: The cost of proactive chlamydia screening is comparable to those of opportunistic screening. Results from this study, which is the first to collect private patient costs associated with a chlamydia screening programme, could be used to inform future policy recommendations and provide unique primary cost data for economic evaluations.

Research paper thumbnail of Cost effectiveness of home based population screening for Chlamydia trachomatis in the UK: economic evaluation of chlamydia screening studies (ClaSS) project

British Medical Journal, 2007

Objective To investigate the cost effectiveness of screening for Chlamydia trachomatis compared w... more Objective To investigate the cost effectiveness of screening for Chlamydia trachomatis compared with a policy of no organised screening in the United Kingdom. Design Economic evaluation using a transmission dynamic mathematical model. Setting Central and southwest England. Participants Hypothetical population of 50 000 men and women, in which all those aged 16-24 years were invited to be screened each year. Main outcome measures Cost effectiveness based on major outcomes averted, defined as pelvic inflammatory disease, ectopic pregnancy, infertility, or neonatal complications. Results The incremental cost per major outcome averted for a programme of screening women only (assuming eight years of screening) was £22 300 (€33 000; $45 000) compared with no organised screening. For a programme screening both men and women, the incremental cost effectiveness ratio was approximately £28 900. Pelvic inflammatory disease leading to hospital admission was the most frequently averted major outcome. The model was highly sensitive to the incidence of major outcomes and to uptake of screening. When both were increased the cost effectiveness ratio fell to £6200 per major outcome averted for screening women only. Conclusions Proactive register based screening for chlamydia is not cost effective if the uptake of screening and incidence of complications are based on contemporary empirical studies, which show lower rates than commonly assumed. These data are relevant to discussions about the cost effectiveness of the opportunistic model of chlamydia screening being introduced in England.