Ryman Shoko | Chinhoyi University Of Technology (original) (raw)

Papers by Ryman Shoko

Genome Editing Tools and Gene Drives, 2021

Uma das maiores crises mundiais de saúde vivenciadas na última década é provocada por um vírus co... more Uma das maiores crises mundiais de saúde vivenciadas na última década é provocada por um vírus conhecido como COVID-19, o vírus provoca diversos danos no sistema respiratório e é altamente transmissível em humanos.A área de orçamentação de uma construtora é uma das áreas mais importantes para poder prosseguir com a viabilidade de um projeto, seja ele de setor público ou privado. Um dos setores mais afetados pela pandemia foi o setor da construção civil uma vez que a construção civil possui diversas particularidades, por sua força motriz depender quase exclusivamente de pessoas e como consequência gerar uma alta concentração no campo de trabalho, esse setor já era bastante volátil a mudanças econômicas.

This paper discusses the bioethics of intellectual property (IP) and intellectual property rights... more This paper discusses the bioethics of intellectual property (IP) and intellectual property rights (IPR) applicable to biotechnology-based IP. It outlines some of the laws that are related to IPR in Zimbabwe and globally. The paper additionally highlights gaps, opportunities and concerns with the laws. Finally, the paper highlights some initiatives already underway in Zimbabwe targeted at promoting entrepreneurship, commercialization and industrialization while proposing strategies that can be used to further promote the generation and granting of biotechnology-related IP and IPR in Zimbabwe.

This book was motivated by the realization that genome editing tools and gene drives can be used ... more This book was motivated by the realization that genome editing tools and gene drives can be used to solve many problems bedeviling Africa and the world at large. Genome editing tools and gene drives are revolutionizing science. However, not many African scientists have written on them. In Nelson Mandela's words, Education is the great engine of personal development. It is through education that the daughter of a peasant can become a doctor, that the son of a mineworker can become the head of the mine, that a child of farm workers can become the president of a great nation. It is what we make out of what we have, not what we are given, that separates one person from another. influenced the writing of this book. We would also like to acknowledge Oklahoma State University, the institute through which the training was provided. In particular, we would like to acknowledge Professor Craig Edwards and his team, the Department of Agricultural Education, Communications and Leadership, Professor Craig Watters and his team and the Spears Business School. Those many books you gave us to share with other Africans back home motivated the writing of this book. We would also like to acknowledge the help given by Dr. Fanuel Songwe and Mr. Vitaris Kodogo during the preparation of this book. The opportunities and access to infrastructure afforded by Lupane State University are greatly appreciated.

All Life, 2021

Reports of snails' resistance to niclosamide appeared recently and finding new molluscici... more Reports of snails' resistance to niclosamide appeared recently and finding new molluscicides becomes necessary. We investigated the molluscicidal effects of Cucurbita maxima seed extracts on Biomphalaria pfeifferi, and Bulinus globosus snails under laboratory conditions. For B. pfeifferi, we tested seed extracts on juvenile and adult snails while only adult B. globosus were available for testing. Snails were exposed to water and crude ethanol extracts for 72 h and significant concentrationdependent mortality rates were observed. The number of B. pfeifferi juveniles collected was not enough for a comprehensive investigation against both solvents. We, therefore, tested them against water extracts only. A lethal concentration of 0.02 mg/mL killed 50% of the snails (LC50) for both water and ethanol extracts on adult B. pfeifferi snails. Our results suggest that pumpkin seed extracts have a significant molluscicidal effect on B. pfeifferi and B. globosus snails. The LC50 values for all the extracts in B. pfeifferi and B. globosus snails are within the threshold set for potential molluscicides by the World Health Organisation. We propose that C.maxima seed extracts be considered as potential molluscicidal agents in Schistosomiasis transmission control.

Genome Editing Tools and Gene Drives, 2021

Although Zimbabwe has a wealth of livestock genetic resources and mostly are quite agriculturally... more Although Zimbabwe has a wealth of livestock genetic resources and mostly are quite agriculturally dependent, there exist clear limitations and challenges regarding animal recording, genetic improvement, production efficiency and the implementation of new technologies, such as genomic selection (GS). Genomic selection incorporates genomic information with phenotypic information (breeding values) to derive genomic estimated breeding values (GEBV) and leads to an increased rate of genetic improvement. The primary principle underlying the application of genomics is that it has the most value for difficult and expensive to measure traits. Maintenance of health will be one of the biggest challenges for efficient livestock production in the next few decades. This challenge will only increase in the face of demand for animal protein, resistance to existing drugs, and the pressure to reduce the use of antibiotics in agriculture. There is probably genetic variation in susceptibility for all d...

The aim of the study was to investigate the molluscicidal effects of pumpkin seeds (Curcurbita ma... more The aim of the study was to investigate the molluscicidal effects of pumpkin seeds (Curcurbita maxima) on adult, juvenile Biomphalaria, and adult Bulinus snails under laboratory conditions. This study was prompted by recent reports on Schistosoma gaining resistance to the commonly administered drug, praziquantel. Snails were exposed to water and ethanol crude extracts for 24 hours and significant concentration-dependent mortality rates were observed. Observations of the snail mortalities continued up to 72 hours. The lethal concentration of 0.02 mg/ml killed 50% of the snails (LC50) for both the water and ethanol extracts on adult Biomphalaria snails. It was noted that the mortalities were not significantly dependent on the time of the snails’ exposure to the extracts. There was a significant difference between the susceptibility of juvenile and adult snails to the ethanol extract (p = 0.016). These results suggest that pumpkin seeds have a significant molluscicidal effect on Biomph...

Genome Editing Tools and Gene Drives, 2021

All Life, 2021

Microalgae are increasingly being preferred as sustainable biomass feedstock for biofuels product... more Microalgae are increasingly being preferred as sustainable biomass feedstock for biofuels production due to their high growth rate and lipid yield. However, optimal production requires the use of economical native microalgal species which are well adapted to local climatic and ecological conditions. Therefore, this study's main objective was to isolate and select local microalgal species for prospective biofuels production. Serial dilution and streak plate techniques were used to isolate four species: Chlorella, Scenedesmus, Oscillatoria and Microcystis from Manyame River, Zimbabwe. The isolates were evaluated for their biomass and lipid productivity under artificial lighting (8:16 h light/dark cycle) and a temperature of 25 ± 3°C. Lipid quantification was done gravimetrically, using hexane as an extraction solvent. Each isolate's performance was compared against that of an imported Chlorella vulgaris strain. Amongst the isolates, Chlorella sp. exhibited a highly competitive growth rate of 0.26 d −1 and lipid yield of 37.16% dry cell weight. In comparison, the imported C. vulgaris had a growth rate of 0.226 d −1 and lipid yield of 35.74% dry cell weight. Although findings suggest that the native Chlorella sp. is the ideal candidate, growth enhancement and genetic engineering techniques may be used to further improve its biomass and lipid yield.

Genome Editing Tools and Gene Drives, 2021

All Life, 2021

Genome Editing Tools and Gene Drives, 2021

All Life, 2021