Journal of Computational Biology, Volume 21 (original) (raw)



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Volume 21, Number 1, January 2014

Jakub Kovác:
On the Complexity of Rearrangement Problems under the Breakpoint Distance. 1-15

Stefano Beretta
, Paola Bonizzoni
, Gianluca Della Vedova
, Yuri Pirola
, Raffaella Rizzi
:
Modeling Alternative Splicing Variants from RNA-Seq Data with Isoform Graphs. 16-40

Conrad J. Burden
, Paul C. Leopardi
, Sylvain Forêt:
The Distribution of Word Matches Between Markovian Sequences with Periodic Boundary Conditions. 41-63

Aïda Ouangraoua
, Mathieu Raffinot:
On the Identification of Conflicting Contiguities in Ancestral Genome Reconstruction. 64-79

Chuanxi Li, Rujing Wang, Peng Chen
, He Huang, Yaru Su:
Interaction Relation Ontology Learning. 80-88

Pawel Górecki
, Oliver Eulenstein:
DrML: Probabilistic Modeling of Gene Duplications. 89-98
Volume 21, Number 2, February 2014

Francesco Bartolucci
, Silvia Pandolfi:
A New Constant Memory Recursion for Hidden Markov Models. 99-117

David J. Galas, Nikita A. Sakhanenko
, Alexander Skupin
, Tomasz M. Ignac:
Describing the Complexity of Systems: Multivariable "Set Complexity" and the Information Basis of Systems Biology. 118-140

Junshan Wang, Ajay Jasra, Maria De Iorio
:
Computational Methods for a Class of Network Models. 141-161

Wajdi Dhifli
, Rabie Saidi
, Engelbert Mephu Nguifo
:
Smoothing 3D Protein Structure Motifs Through Graph Mining and Amino Acid Similarities. 162-172

Nissan Levtov, Sandeep Amberkar
, Zakharia M. Frenkel, Lars Kaderali
, Zeev Volkovich
:
Detecting Non-Uniform Clusters in Large-Scale Interaction Graphs. 173-183
Volume 21, Number 3, March 2014

Chaozhi Zheng
, Mary K. Kuhner, Elizabeth A. Thompson:
Joint Inference of Identity by Descent Along Multiple Chromosomes from Population Samples. 185-200

Yang Ding, William Andrew Lorenz, Iván Dotú, Evan Senter, Peter Clote:
Computing the Probability of RNA Hairpin and Multiloop Formation. 201-218

Heewook Lee, Ellen Popodi, Patricia L. Foster
, Haixu Tang:
Detection of Structural Variants Involving Repetitive Regions in the Reference Genome. 219-233

Mu-Fen Hsieh, Sing-Hoi Sze:
Finding Alignments of Conserved Graphlets in Protein Interaction Networks. 234-246

Dariusz Plewczynski
, Anna Philips
, Marcin von Grotthuss, Leszek Rychlewski, Krzysztof Ginalski:
HarmonyDOCK: The Structural Analysis of Poses in Protein-Ligand Docking. 247-256

Guillermo Peris
, Andrés Marzal:
Statistical Significance of Normalized Global Alignment. 257-268

Andrew F. Neuwald:
A Bayesian Sampler for Optimization of Protein Domain Hierarchies. 269-286
Volume 21, Number 4, April 2014

Andrew F. Neuwald:
Evaluating, Comparing, and Interpreting Protein Domain Hierarchies. 287-302

Lavanya Kannan, Ward C. Wheeler:
Exactly Computing the Parsimony Scores on Phylogenetic Networks Using Dynamic Programming. 303-319

Xun Wang
, Ying Miao, Minquan Cheng:
Finding Motifs in DNA Sequences Using Low-Dispersion Sequences. 320-329

Matteo Comin
, Montse Farreras
:
Parallel Continuous Flow: A Parallel Suffix Tree Construction Tool for Whole Genomes. 330-344

Seyoung Kim, Eric P. Xing:
Exploiting Genome Structure in Association Analysis. 345-360

Robert Hochberg, Treena Larrew Milam:
Data Structures for Parsimony Correlation and Biosequence Co-Evolution. 361-369
Volume 21, Number 5, May 2014

Andrea Califano
, Manolis Kellis, Gustavo Stolovitzky:
RECOMB/ISCB Systems Biology, Regulatory Genomics, and DREAM 2013 Special Issue. 371-372

Patrick K. O'Neill, Robert Forder, Ivan Erill
:
Informational Requirements for Transcriptional Regulation. 373-384

Zhiyong Wang, Jinbo Xu, Xinghua Shi:
Finding Alternative Expression Quantitative Trait Loci by Exploring Sparse Model Space. 385-393

Arnon Mazza, Irit Gat-Viks, Roded Sharan
:
Elucidating Influenza Inhibition Pathways via Network Reconstruction. 394-404
Volume 21, Number 6, June 2014

John G. Cleary, Ross Braithwaite, Kurt Gaastra, Brian S. Hilbush, Stuart Inglis, Sean A. Irvine, Alan Jackson, Richard Littin, Sahar Nohzadeh-Malakshah, Mehul Rathod, David Ware, Len Trigg, Francisco M. de la Vega:
Joint Variant and De Novo Mutation Identification on Pedigrees from High-Throughput Sequencing Data. 405-419

Sebastian Klie, Zoran Nikoloski
, Joachim Selbig:
Biological Cluster Evaluation for Gene Function Prediction. 428-445

Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh:
Border Length Minimization Problem on a Square Array. 446-455

Nivit Gill, Shailendra Singh, Trilok Chand Aseri:
Computational Disease Gene Prioritization: An Appraisal. 456-465

Abdul Arif Khan
:
In Silico Prediction of Escherichia coli Proteins Targeting the Host Cell Nucleus, with Special Reference to Their Role in Colon Cancer Etiology. 466-475
Volume 21, Number 7, July 2014

Jérôme Waldispühl
, Charles W. O'Donnell, Sebastian Will, Srinivas Devadas, Rolf Backofen, Bonnie Berger:
Simultaneous Alignment and Folding of Protein Sequences. 477-491

Md. Muksitul Haque, Michael K. Skinner, Lawrence B. Holder:
Imbalanced Class Learning in Epigenetics. 492-507

Daniel Gamermann
, Arnau Montagud
, J. Alberto Conejero
, Javier F. Urchueguía
, Pedro Fernández de Córdoba
:
New Approach for Phylogenetic Tree Recovery Based on Genome-Scale Metabolic Networks. 508-519

Fabien de Montgolfier, Mathieu Raffinot, Irena Rusu:
Easy Identification of Generalized Common and Conserved Nested Intervals. 520-533

Anna Zhukova, David James Sherman
:
Knowledge-based Generalization of Metabolic Models. 534-547

Wen-Shyong Tzou
, Ying-Tsang Lo
, Tun-Wen Pai, Chin-Hua Hu
, Chung-Hao Li:
Stochastic Simulation of Notch Signaling Reveals Novel Factors That Mediate the Differentiation of Neural Stem Cells. 548-567
Volume 21, Number 8, August 2014

Alexei A. Sharov
, Akira Nishiyama, Yong Qian, Dawood B. Dudekula
, Dan L. Longo, David Schlessinger, Minoru S. H. Ko:
Chromatin Properties of Regulatory DNA Probed by Manipulation of Transcription Factors. 569-577

Yu Zheng, Louxin Zhang:
Are the Duplication Cost and Robinson-Foulds Distance Equivalent? 578-590

Hillary S. W. Han, Thomas J. X. Li, Christian M. Reidys:
Combinatorics of _γ_-Structures. 591-608

Cuncong Zhong, Shaojie Zhang
:
Simultaneous Folding of Alternative RNA Structures with Mutual Constraints: An Application to Next-Generation Sequencing-based RNA Structure Probing. 609-621

Nikita Alexeev
, Peter Zograf:
Random Matrix Approach to the Distribution of Genomic Distance. 622-631

Ponne Saravanaraman
, Raj Kumar Chinnadurai
, Rathanam Boopathy:
A New Role for the Nonpathogenic Nonsynonymous Single-Nucleotide Polymorphisms of Acetylcholinesterase in the Treatment of Alzheimer's Disease: A Computational Study. 632-647
Volume 21, Number 9, September 2014

Benjamin M. M. Fu, Christian M. Reidys:
Shapes of Interacting RNA Complexes. 649-664

Maria Brigida Ferraro
, Marco Savarese
, Giuseppina Di Fruscio, Vincenzo Nigro
, Mario Rosario Guarracino
:
Prediction of Rare Single-Nucleotide Causative Mutations for Muscular Diseases in Pooled Next-Generation Sequencing Experiments. 665-675

Jan Irvahn, Vladimir N. Minin
:
Phylogenetic Stochastic Mapping Without Matrix Exponentiation. 676-690

Yunzhang Huo, Ping Ji
:
Continuous-Time Markov Chain-Based Flux Analysis in Metabolism. 691-698

Alexandru Agapie, Anca Andreica
, Marius Giuclea:
Probabilistic Cellular Automata. 699-708

Albert Vexler
, Xiwei Chen, Jihnhee Yu:
Evaluations and Comparisons of Treatment Effects Based on Best Combinations of Biomarkers with Applications to Biomedical Studies. 709-721
Volume 21, Number 10, October 2014

Josh Voorkamp:
Maximal Acyclic Agreement Forests. 723-731

Loni Philip Tabb, Wei Zhao
, Jingyu Huang, Gail L. Rosen
:
Characterizing the Empirical Distribution of Prokaryotic Genome _n_-mers in the Presence of Nullomers. 732-740

Ziva Stepancic:
Enhancing Gibbs Sampling Method for Motif Finding in DNA with Initial Graph Representation of Sequences. 741-752

Hari Ram, Alok Kumar, Lebin Thomas
, Ved Pal Singh:
In silico Approach to Study Adaptive Divergence in Nucleotide Composition of the 16S rRNA Gene Among Bacteria Thriving Under Different Temperature Regimes. 753-759

Alex Radu, Michael A. Charleston
:
Node Fingerprinting: An Efficient Heuristic for Aligning Biological Networks. 760-770

Peican Zhu
, Jie Han:
Asynchronous Stochastic Boolean Networks as Gene Network Models. 771-783
Volume 21, Number 11, November 2014

Takanori Hasegawa, Tomoya Mori, Rui Yamaguchi, Seiya Imoto, Satoru Miyano
, Tatsuya Akutsu
:
An Efficient Data Assimilation Schema for Restoration and Extension of Gene Regulatory Networks Using Time-Course Observation Data. 785-798

Amir Carmel, Noa Musa-Lempel, Dekel Tsur
, Michal Ziv-Ukelson:
The Worst Case Complexity of Maximum Parsimony. 799-808

Bogumil Konopka, Tomasz Golda, Malgorzata Kotulska:
Evaluating the Significance of Protein Functional Similarity Based on Gene Ontology. 809-822

José Santos Reyes, Pablo Villot, Martín Diéguez:
Emergent Protein Folding Modeled with Evolved Neural Cellular Automata Using the 3D HP Model. 823-845

Nha Nguyen
, An P. N. Vo, Kyoung-Jae Won
:
A Wavelet Approach to Detect Enriched Regions and Explore Epigenomic Landscapes. 846-854

Katrin Illner, Christiane Fuchs
, Fabian J. Theis
:
Bayesian Blind Source Separation for Data with Network Structure. 855-865
Volume 21, Number 12, December 2014

Changchuan Yin
, Xuemeng E. Yin, Jiasong Wang:
A Novel Method for Comparative Analysis of DNA Sequences by Ramanujan-Fourier Transform. 867-879

Eman Badr
, Lenwood S. Heath:
Identifying Splicing Regulatory Elements with de Bruijn Graphs. 880-897

Alexia Kakourou, Werner Vach
, Bart J. A. Mertens:
Combination Approaches Improve Predictive Performance of Diagnostic Rules for Mass-Spectrometry Proteomic Data. 898-914

William Y. C. Chen, Qiang-Hui Guo, Lisa Hui Sun, Jian Wang:
Zigzag Stacks and _m_-Regular Linear Stacks. 915-935

Huda Amin Maghawry
, Mostafa G. M. Mostafa
, Tarek F. Gharib:
A New Protein Structure Representation for Efficient Protein Function Prediction. 936-946

Laurent Noé
, Donald E. K. Martin:
A Coverage Criterion for Spaced Seeds and Its Applications to Support Vector Machine String Kernels and _k_-Mer Distances. 947-963

Lizhen Liu, Xuemin Dai, Hanshi Wang, Wei Song, Jingli Lu:
A Weighted Multipath Measurement Based on Gene Ontology for Estimating Gene Products Similarity. 964-974

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