haluk berk | Dokuz Eylül University (original) (raw)
Papers by haluk berk
Acta Orthopaedica et Traumatologica Turcica
He was a kind, realistic and honest person with a sharp and practical mind and a generous and con... more He was a kind, realistic and honest person with a sharp and practical mind and a generous and considerate soul. Along with his many qualities as a passionate teacher, a proficient surgeon, a mentor and a family man, Önder Kılıçoğlu was certainly the most prominent figure for our journal, contributing and working hard at every level, initially a technical board member then the editor-in-chief starting from 1990 until this day. The connection between Kılıçoğlu and Acta Ortopaedica et Traumatologica Turcica is so intense, that their histories are intertwined. Dr. Önder Kılıçoğlu was born in Istanbul, on August 26, 1967. He was the eldest of three children of Editorial In Memoriam
Acta Orthopaedica et Traumatologica Turcica, 2006
We evaluated the relationship between functional objective and patient-based subjective assessmen... more We evaluated the relationship between functional objective and patient-based subjective assessments and quality of life in patients with lumbar spinal stenosis (LSS). Thirty patients (25 females, 5 males; mean age 62+/-9 years; range 41-78 years) were prospectively studied. All were diagnosed as having LSS by clinical and radiological evaluations. Pain was assessed by a visual analog scale. The patients were evaluated by the two-staged treadmill exercise tolerance (TET) test, SF-36 health status survey, and Oswestry Disability Index (ODI). The relationships between the TET test, which is an objective functional assessment, and patient-based assessments (SF-36 and ODI), pain and age were investigated. There were significant differences between the functional grades of the patients at the speed of 1.9 km/hour with respect to ODI scores, the physical component scale of SF-36, age, and the preferred speed of the patients (p<0.05). These differences emerged from the fourth functional ...
Educational objectives: Pedicle screw fixation in Thoracic spine Types of educational activities:... more Educational objectives: Pedicle screw fixation in Thoracic spine Types of educational activities: There will be live surgeries, case discussions and lectures on day one and hands on workshop activities on cadavers as well as sawbones on day two. Day 1 Presentations Functional anatomy of thoracic and lumbar spine Pedicular anatomy from T1 to S1 Structures at risk! Radiology Free hand or navigation Clinical examples Cadaver and saw-bone workshop Hands-on: pedicle screw application with different instrumentations. Day 2 Surgery Case discussions Adjurn
Department of Orthopedics and TraumatologyObjectives: We evaluated the relationship between funct... more Department of Orthopedics and TraumatologyObjectives: We evaluated the relationship between function-al objective and patient-based subjective assessments andquality of life in patients with lumbar spinal stenosis (LSS).Methods:Thirty patients (25 females, 5 males; mean age62±9 years; range 41-78 years) were prospectively studied.All were diagnosed as having LSS by clinical and radiologi-cal evaluations. Pain was assessed by a visual analog scale.The patients were evaluated by two-staged treadmill exercisetolerance (TET) test, SF-36 health status survey, andOswestry Disability Index (ODI). The relationships betweenthe TET test, which is an objective functional assessment,and patient-based assessments (SF-36 and ODI), pain andage were investigated.R e su l t s :There were significant differences between the func-tional grades of the patients at the speed of 1.9 km/hour withrespect to ODI scores, the physical component scale of SF-36,age, and the preferred speed of the patients (p<...
Ali Asma, Md Alfred I DuPont Hospital 1600 Rockland Rd, Wilmington, DE 19803, Phone: (302) 39
Results: There were significant differences between the functional grades of the patients at the ... more Results: There were significant differences between the functional grades of the patients at the speed of 1.9 km/hour with respect to ODI scores, the physical component scale of SF-36, age, and the preferred speed of the patients (p<0.05). These differences emerged from the fourth functional stage (p<0.01). Oswestry disability scores and the physical component scores of SF-36 worsened in parallel with the stages of the TET test. The preferred speed of the patients at the TET test was positively correlated with the physical component scores of SF-36 and negatively correlated with Oswestry disability scores (p<0.05). There was a negative correlation between the physical component scores of SF-36 and Oswestry disability scores (p<0.05). Conclusion: The TET test used to determine the functional capacity seems to be correlated well with subjective patientbased assessments. This objective tool, when combined with subjective assessments, may be helpful in the evaluation and tre...
PurposeTo produce a cross-culturally adapted and validated Turkish version of The Core Outcome Me... more PurposeTo produce a cross-culturally adapted and validated Turkish version of The Core Outcome Measure Index (COMI) Back questionnaire.MethodsNinety-six Turkish-speaking patients with non-specific low back pain (LBP) were recruited from orthopedic and physical therapy outpatient clinics in a public hospital. They completed a booklet of questionnaires containing Turkish version of COMI, adjectival pain scale, Roland Morris disability questionnaire, European 5 Dimension Questionnaire and brief version of World Health Organization Quality of Life Questionnaire. Within following 7–14 days, 67 patients, reported no or minimal changes in their back pain status, completed the Turkish COMI again to assess reproducibility.ResultsData quality was good with very few missing answers. COMI summary index score displayed 3% floor effects and no ceiling effects. The correlations between the COMI summary index score and each of the full instrument whole scores were found to be excellent to very good...
Amac: Calismanin amaci Dokuz Eylul Universitesi Tip Fakultesi serebral palsipolikliniginde izlene... more Amac: Calismanin amaci Dokuz Eylul Universitesi Tip Fakultesi serebral palsipolikliniginde izlenen hastalarin genel ozelliklerinin arastirilmasidir.Gerec ve yontem: Dokuz Eylul Universitesi Tip Fakultesi Fiziksel Tip ve RehabilitasyonAnabilim Dali ve Ortopedi ve Travmatoloji Anabilim Dali tarafindan yurutulen serebral palsipolikliniginde 2002 - 2006 yillari arasinda standart muayene yontemleri ile izlenen 150 hastaretrospektif olarak degerlendirildi. Bulgular: Hastalarin yas ortalamalari 7,56 ± 4,68 yil ve tani konma yasi 4,95 ± 4,86 ayolarak saptandi. Etiyolojik faktorler acisindan bakildiginda %60,1 prenatal, %29,4 perinatalve %11,5 olguda postnatal nedenler sorumlu olarak bulundu. Olgularin fizik tedavi verehabilitasyona baslama yasi 2,89 ± 5,96 yil idi ve %80,5’inin bir rehabilitasyon merkezindeduzenli bir tedavi hizmeti aldigi saptandi. Serebral palsi tipi acisindan yapilan degerlendirmede %20,7’sini hemiplejik tip, %42’sini diplejik tip ve %37,3’unu de tum vucut tutulumuolan kuadriplejik olgularin olusturdugu goruldu. Olgularin 42 (%28)’sinde cerrahi ve 50 (%33,3)’sinde botulinum toksin enjeksiyonu uygulamasi yapilmisti. Sonuc: Serebral palsi cocukluk caginda en sik gorulen ve onemli sakatlik nedeni olabilenbir hastaliktir. Bu olgularin duzenli olarak izlemi ve gerekli tedavi yaklasimlarinin zamanindauygulanmasi degerlendirme ve tedavisinde bir multidisipliner yaklasim gerektirmektedir
Acta Orthopaedica et Traumatologica Turcica, 2012
... Haluk BERK Dokuz Eylül Üniversitesi T›p Fakültesi, Ortopedi ve Travmatoloji Anabilim Dal›, ‹z... more ... Haluk BERK Dokuz Eylül Üniversitesi T›p Fakültesi, Ortopedi ve Travmatoloji Anabilim Dal›, ‹zmir ... J Bone Joint Surg Am 1959;41:291-302. 4. Gülflen M. Özkan C, Alt›n M. Ankilozan spondilitte ba¤l› ki-fotik deformite tedavisinde lomber transpediküler kapal› ka-ma osteotomisi. ...
Spine Surgery and Related Research
Introduction: The use of the antifibrinolytic agent tranexamic acid has positive effects on bleed... more Introduction: The use of the antifibrinolytic agent tranexamic acid has positive effects on bleeding control, but our knowledge is still limited regarding how fibrinolysis suppression changes the process of bone formation and the quality of bone. Because of the several side effects of systemic tranexamic acid, topical usage has been established in several procedures. This study aimed to investigate the effect of local tranexamic acid on vertebral fusion by using macroscopic, radiologic, and microscopic techniques. We also attempted to determine the safe dose range in case some doses had negative effects on fusion. Methods: Twenty-eight Wistar albino rats underwent intertransverse fusion. All rats were randomized into four groups: groups treated with local tranexamic acid doses of 1 mg/kg (D1), 10 mg/kg (D10), and 100 mg/kg (D100) and the control group with no drug (D0). At the end of the eighth week, all rats were sacrificed for evaluation in terms of palpation, mammography, and histopathologic analysis. Results: The manual palpation results presented with lower fusion rates in D10 and D100 groups than in the control group. Radiological examination results were significantly higher in the control group. The histopathologic examination revealed no significant differences between groups in the percent of new bone formation. Conclusion: Our results showed that local administration of tranexamic acid reduced the quality and stability of fusion without a delay in bone formation. However, doses of 1 mg/kg did not reduce the stability in the palpation test. Our findings suggest that 1 mg/kg dose is a critical threshold above which tranexamic acid reduced the bone healing process of fusion and that surgeons should consider the doses of local tranexamic acid during surgery.
Acta Orthopaedica et Traumatologica Turcica
Asian Spine Journal
This study investigates the benefits of supplemental hook fixation (SHF) on short-segment pedicle... more This study investigates the benefits of supplemental hook fixation (SHF) on short-segment pedicle instrumentation (SSPI) in relation to anterior strut graft positioning. In addition, it seeks to determine whether the integrity of the posterior ligamentous complex (PLC) affects the stability of the spinal construct. Overview of Literature: Implant and/or bone failure with progressive kyphotic deformity after SSPI is common. To prevent this, several approaches are available, including SHF, anterior strut grafting, use of longer spinal constructs, and extension of the fusion to additional adjacent segments. Methods: A total of eight calf spines were instrumented with SSPI (n=4) and SHF (n=4) with strain gauges on the implants. Strain measurements were performed under axial compression in the following order: intact spine, corpectomy, ventral positioned strut grafting, posterior positioned strut grafting, ventral positioned grafting with resected PLC, and corpectomy with resected PLC. Results: The SHF group showed slightly lower strain values than SSPI in instrumented corpectomy-only specimens, but there were no statistically significant differences between them (p>0.05). The SHF group was significantly more stable than SSPI when strut grafting is employed, regardless of the location of the grafts (p=0.000). In the SSPI group, ventral positioning of the graft contributed significantly to the stability (p=0.000). There was no statistically significant difference between the ventral or posterior positioning of the graft in the SHF group (p=0.187). In addition, the integrity of the PLC did not affect stability in either group (p>0.005). Conclusions: Although not statistically significant, our investigation demonstrated that the most stable method was the SHF along with ventral positioned strut graft. However, if the SSPI is the treatment of choice, ventral positioned strut graft support will be useful in minimizing the risk of implant failure and progressive kyphotic deformity.
Neurological Sciences and Neurophysiology
The aim of this study was to investigate the validity and reliability of the Turkish version of t... more The aim of this study was to investigate the validity and reliability of the Turkish version of the Modified House Classification System (MHCS) in children with cerebral palsy (CP). Methods: Forty-five patients were evaluated by two physicians and the intra-rater reliability within a subgroup of 21 patients was assessed. Intra-rater and inter-rater reliability were also analyzed using intraclass correlation coefficient (ICC), and Spearman's rank-order correlation test was used to indicate an association between the Manual Ability Classification System (MACS) and the MHCS. Internal consistency was measured using Cronbach's alpha. Results: Intra-rater and inter-rater reliability and internal consistency of the MHCS were found to be excellent with a Cronbach's alpha value of 0.89 and ICC value of 0.97 and 0.98 respectively. A significant correlation was found between the MACS and MHCS (p<0.001, r=-0.805). Conclusion: The inter-rater and intra-rater reliability of Turkish version of the MHCS were found to be high regarding the assessment of Turkish children with CP.
Acta Orthopaedica Et Traumatologica Turcica, 2011
... fiekil 2. 1996 2005 y›llar› aras›nda Eurospine kongrelerine gön-derilen özet, kabul oran› ve ... more ... fiekil 2. 1996 2005 y›llar› aras›nda Eurospine kongrelerine gön-derilen özet, kabul oran› ve yay›na kabul oranlar›n› gös-teren grafikte özet kabul oran› ile yay›na kabul aras›n ... Sivan M, Smith M, Bavikatte G, Bradley L. The academic value of rehabilitation medicine meetings. ...
Journal of Pediatric Orthopaedics, 2016
Traditional growing rods have a reported wound and implant complication rate as high as 58%. It i... more Traditional growing rods have a reported wound and implant complication rate as high as 58%. It is unclear whether the use of magnetically controlled growing rods (MCGR) will affect this rate. This study was performed to characterize surgical complications following MCGR in early onset scoliosis. A multicenter retrospective review of MCGR cases was performed. Inclusion criteria were: (1) diagnosis of early onset scoliosis of any etiology; (2) 10 years and younger at time of index surgery; (3) preoperative major curve size &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;30 degrees; (4) preoperative thoracic spine height &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;22 cm. Complications were categorized as wound related and instrumentation related. Complications were also classified as early (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;6 mo from index surgery) versus late (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;6 mo). Distraction technique and interval of distraction was surgeon preference without standardization across sites. Fifty-four MCGR patients met inclusion criteria. There were 30 primary and 24 conversion procedures. Mean age at initial surgery was 7.3 years (range, 2.4 to 11 y), and mean duration of follow-up 19.4 months. Twenty-one (38.8%) of 54 patients had at least 1 complication. Fifteen (27.8%) had at least 1 revision surgery. Six (11.1%) had broken rods (2 to 4.5 and 4 to 5.5 mm rods); two 5.5 mm rods failed early (4 mo) and 4 late (mean=14.5 mo). Six (11.1%) patients experienced 1 episode of lack or loss of lengthening, of which 4 patients subsequently lengthened. Seven patients (13.0%) had either proximal or distal fixation-related complication at average of 8.4 months. Two patients (3.7%) had infections requiring incision and drainage; 1 early (2 wk) with wound drainage and 1 late (8 mo). The late case required removal of one of the dual rods. This study shows that compared with traditional growing rods, MCGR has a lower infection rate (3.7% vs. 11.1%). MCGR does not appear to prevent common implant-related complications such as rod or foundation failure. The long-term implication remains to be determined. Level IV.
Acta Orthopaedica Et Traumatologica Turcica, Feb 1, 2004
During the past two decades, there has been a significant increase in sports participation by ped... more During the past two decades, there has been a significant increase in sports participation by pediatric athletes. Spinal injuries thus have become a great concern. The unique nature of the pediatric spine should be well-recognized and low back pain in a pediatric athlete should therefore be taken seriously and evaluated thoroughly. In this review article, sports-related lumbar spine problems will be covered including overuse injuries, spondylolysis, pars stress fractures, spondylolysthesis, and lumbar disc herniation. Early identification of these problems will eventually minimize these injuries.
Acta Orthopaedica et Traumatologica Turcica
He was a kind, realistic and honest person with a sharp and practical mind and a generous and con... more He was a kind, realistic and honest person with a sharp and practical mind and a generous and considerate soul. Along with his many qualities as a passionate teacher, a proficient surgeon, a mentor and a family man, Önder Kılıçoğlu was certainly the most prominent figure for our journal, contributing and working hard at every level, initially a technical board member then the editor-in-chief starting from 1990 until this day. The connection between Kılıçoğlu and Acta Ortopaedica et Traumatologica Turcica is so intense, that their histories are intertwined. Dr. Önder Kılıçoğlu was born in Istanbul, on August 26, 1967. He was the eldest of three children of Editorial In Memoriam
Acta Orthopaedica et Traumatologica Turcica, 2006
We evaluated the relationship between functional objective and patient-based subjective assessmen... more We evaluated the relationship between functional objective and patient-based subjective assessments and quality of life in patients with lumbar spinal stenosis (LSS). Thirty patients (25 females, 5 males; mean age 62+/-9 years; range 41-78 years) were prospectively studied. All were diagnosed as having LSS by clinical and radiological evaluations. Pain was assessed by a visual analog scale. The patients were evaluated by the two-staged treadmill exercise tolerance (TET) test, SF-36 health status survey, and Oswestry Disability Index (ODI). The relationships between the TET test, which is an objective functional assessment, and patient-based assessments (SF-36 and ODI), pain and age were investigated. There were significant differences between the functional grades of the patients at the speed of 1.9 km/hour with respect to ODI scores, the physical component scale of SF-36, age, and the preferred speed of the patients (p<0.05). These differences emerged from the fourth functional ...
Educational objectives: Pedicle screw fixation in Thoracic spine Types of educational activities:... more Educational objectives: Pedicle screw fixation in Thoracic spine Types of educational activities: There will be live surgeries, case discussions and lectures on day one and hands on workshop activities on cadavers as well as sawbones on day two. Day 1 Presentations Functional anatomy of thoracic and lumbar spine Pedicular anatomy from T1 to S1 Structures at risk! Radiology Free hand or navigation Clinical examples Cadaver and saw-bone workshop Hands-on: pedicle screw application with different instrumentations. Day 2 Surgery Case discussions Adjurn
Department of Orthopedics and TraumatologyObjectives: We evaluated the relationship between funct... more Department of Orthopedics and TraumatologyObjectives: We evaluated the relationship between function-al objective and patient-based subjective assessments andquality of life in patients with lumbar spinal stenosis (LSS).Methods:Thirty patients (25 females, 5 males; mean age62±9 years; range 41-78 years) were prospectively studied.All were diagnosed as having LSS by clinical and radiologi-cal evaluations. Pain was assessed by a visual analog scale.The patients were evaluated by two-staged treadmill exercisetolerance (TET) test, SF-36 health status survey, andOswestry Disability Index (ODI). The relationships betweenthe TET test, which is an objective functional assessment,and patient-based assessments (SF-36 and ODI), pain andage were investigated.R e su l t s :There were significant differences between the func-tional grades of the patients at the speed of 1.9 km/hour withrespect to ODI scores, the physical component scale of SF-36,age, and the preferred speed of the patients (p<...
Ali Asma, Md Alfred I DuPont Hospital 1600 Rockland Rd, Wilmington, DE 19803, Phone: (302) 39
Results: There were significant differences between the functional grades of the patients at the ... more Results: There were significant differences between the functional grades of the patients at the speed of 1.9 km/hour with respect to ODI scores, the physical component scale of SF-36, age, and the preferred speed of the patients (p<0.05). These differences emerged from the fourth functional stage (p<0.01). Oswestry disability scores and the physical component scores of SF-36 worsened in parallel with the stages of the TET test. The preferred speed of the patients at the TET test was positively correlated with the physical component scores of SF-36 and negatively correlated with Oswestry disability scores (p<0.05). There was a negative correlation between the physical component scores of SF-36 and Oswestry disability scores (p<0.05). Conclusion: The TET test used to determine the functional capacity seems to be correlated well with subjective patientbased assessments. This objective tool, when combined with subjective assessments, may be helpful in the evaluation and tre...
PurposeTo produce a cross-culturally adapted and validated Turkish version of The Core Outcome Me... more PurposeTo produce a cross-culturally adapted and validated Turkish version of The Core Outcome Measure Index (COMI) Back questionnaire.MethodsNinety-six Turkish-speaking patients with non-specific low back pain (LBP) were recruited from orthopedic and physical therapy outpatient clinics in a public hospital. They completed a booklet of questionnaires containing Turkish version of COMI, adjectival pain scale, Roland Morris disability questionnaire, European 5 Dimension Questionnaire and brief version of World Health Organization Quality of Life Questionnaire. Within following 7–14 days, 67 patients, reported no or minimal changes in their back pain status, completed the Turkish COMI again to assess reproducibility.ResultsData quality was good with very few missing answers. COMI summary index score displayed 3% floor effects and no ceiling effects. The correlations between the COMI summary index score and each of the full instrument whole scores were found to be excellent to very good...
Amac: Calismanin amaci Dokuz Eylul Universitesi Tip Fakultesi serebral palsipolikliniginde izlene... more Amac: Calismanin amaci Dokuz Eylul Universitesi Tip Fakultesi serebral palsipolikliniginde izlenen hastalarin genel ozelliklerinin arastirilmasidir.Gerec ve yontem: Dokuz Eylul Universitesi Tip Fakultesi Fiziksel Tip ve RehabilitasyonAnabilim Dali ve Ortopedi ve Travmatoloji Anabilim Dali tarafindan yurutulen serebral palsipolikliniginde 2002 - 2006 yillari arasinda standart muayene yontemleri ile izlenen 150 hastaretrospektif olarak degerlendirildi. Bulgular: Hastalarin yas ortalamalari 7,56 ± 4,68 yil ve tani konma yasi 4,95 ± 4,86 ayolarak saptandi. Etiyolojik faktorler acisindan bakildiginda %60,1 prenatal, %29,4 perinatalve %11,5 olguda postnatal nedenler sorumlu olarak bulundu. Olgularin fizik tedavi verehabilitasyona baslama yasi 2,89 ± 5,96 yil idi ve %80,5’inin bir rehabilitasyon merkezindeduzenli bir tedavi hizmeti aldigi saptandi. Serebral palsi tipi acisindan yapilan degerlendirmede %20,7’sini hemiplejik tip, %42’sini diplejik tip ve %37,3’unu de tum vucut tutulumuolan kuadriplejik olgularin olusturdugu goruldu. Olgularin 42 (%28)’sinde cerrahi ve 50 (%33,3)’sinde botulinum toksin enjeksiyonu uygulamasi yapilmisti. Sonuc: Serebral palsi cocukluk caginda en sik gorulen ve onemli sakatlik nedeni olabilenbir hastaliktir. Bu olgularin duzenli olarak izlemi ve gerekli tedavi yaklasimlarinin zamanindauygulanmasi degerlendirme ve tedavisinde bir multidisipliner yaklasim gerektirmektedir
Acta Orthopaedica et Traumatologica Turcica, 2012
... Haluk BERK Dokuz Eylül Üniversitesi T›p Fakültesi, Ortopedi ve Travmatoloji Anabilim Dal›, ‹z... more ... Haluk BERK Dokuz Eylül Üniversitesi T›p Fakültesi, Ortopedi ve Travmatoloji Anabilim Dal›, ‹zmir ... J Bone Joint Surg Am 1959;41:291-302. 4. Gülflen M. Özkan C, Alt›n M. Ankilozan spondilitte ba¤l› ki-fotik deformite tedavisinde lomber transpediküler kapal› ka-ma osteotomisi. ...
Spine Surgery and Related Research
Introduction: The use of the antifibrinolytic agent tranexamic acid has positive effects on bleed... more Introduction: The use of the antifibrinolytic agent tranexamic acid has positive effects on bleeding control, but our knowledge is still limited regarding how fibrinolysis suppression changes the process of bone formation and the quality of bone. Because of the several side effects of systemic tranexamic acid, topical usage has been established in several procedures. This study aimed to investigate the effect of local tranexamic acid on vertebral fusion by using macroscopic, radiologic, and microscopic techniques. We also attempted to determine the safe dose range in case some doses had negative effects on fusion. Methods: Twenty-eight Wistar albino rats underwent intertransverse fusion. All rats were randomized into four groups: groups treated with local tranexamic acid doses of 1 mg/kg (D1), 10 mg/kg (D10), and 100 mg/kg (D100) and the control group with no drug (D0). At the end of the eighth week, all rats were sacrificed for evaluation in terms of palpation, mammography, and histopathologic analysis. Results: The manual palpation results presented with lower fusion rates in D10 and D100 groups than in the control group. Radiological examination results were significantly higher in the control group. The histopathologic examination revealed no significant differences between groups in the percent of new bone formation. Conclusion: Our results showed that local administration of tranexamic acid reduced the quality and stability of fusion without a delay in bone formation. However, doses of 1 mg/kg did not reduce the stability in the palpation test. Our findings suggest that 1 mg/kg dose is a critical threshold above which tranexamic acid reduced the bone healing process of fusion and that surgeons should consider the doses of local tranexamic acid during surgery.
Acta Orthopaedica et Traumatologica Turcica
Asian Spine Journal
This study investigates the benefits of supplemental hook fixation (SHF) on short-segment pedicle... more This study investigates the benefits of supplemental hook fixation (SHF) on short-segment pedicle instrumentation (SSPI) in relation to anterior strut graft positioning. In addition, it seeks to determine whether the integrity of the posterior ligamentous complex (PLC) affects the stability of the spinal construct. Overview of Literature: Implant and/or bone failure with progressive kyphotic deformity after SSPI is common. To prevent this, several approaches are available, including SHF, anterior strut grafting, use of longer spinal constructs, and extension of the fusion to additional adjacent segments. Methods: A total of eight calf spines were instrumented with SSPI (n=4) and SHF (n=4) with strain gauges on the implants. Strain measurements were performed under axial compression in the following order: intact spine, corpectomy, ventral positioned strut grafting, posterior positioned strut grafting, ventral positioned grafting with resected PLC, and corpectomy with resected PLC. Results: The SHF group showed slightly lower strain values than SSPI in instrumented corpectomy-only specimens, but there were no statistically significant differences between them (p>0.05). The SHF group was significantly more stable than SSPI when strut grafting is employed, regardless of the location of the grafts (p=0.000). In the SSPI group, ventral positioning of the graft contributed significantly to the stability (p=0.000). There was no statistically significant difference between the ventral or posterior positioning of the graft in the SHF group (p=0.187). In addition, the integrity of the PLC did not affect stability in either group (p>0.005). Conclusions: Although not statistically significant, our investigation demonstrated that the most stable method was the SHF along with ventral positioned strut graft. However, if the SSPI is the treatment of choice, ventral positioned strut graft support will be useful in minimizing the risk of implant failure and progressive kyphotic deformity.
Neurological Sciences and Neurophysiology
The aim of this study was to investigate the validity and reliability of the Turkish version of t... more The aim of this study was to investigate the validity and reliability of the Turkish version of the Modified House Classification System (MHCS) in children with cerebral palsy (CP). Methods: Forty-five patients were evaluated by two physicians and the intra-rater reliability within a subgroup of 21 patients was assessed. Intra-rater and inter-rater reliability were also analyzed using intraclass correlation coefficient (ICC), and Spearman's rank-order correlation test was used to indicate an association between the Manual Ability Classification System (MACS) and the MHCS. Internal consistency was measured using Cronbach's alpha. Results: Intra-rater and inter-rater reliability and internal consistency of the MHCS were found to be excellent with a Cronbach's alpha value of 0.89 and ICC value of 0.97 and 0.98 respectively. A significant correlation was found between the MACS and MHCS (p<0.001, r=-0.805). Conclusion: The inter-rater and intra-rater reliability of Turkish version of the MHCS were found to be high regarding the assessment of Turkish children with CP.
Acta Orthopaedica Et Traumatologica Turcica, 2011
... fiekil 2. 1996 2005 y›llar› aras›nda Eurospine kongrelerine gön-derilen özet, kabul oran› ve ... more ... fiekil 2. 1996 2005 y›llar› aras›nda Eurospine kongrelerine gön-derilen özet, kabul oran› ve yay›na kabul oranlar›n› gös-teren grafikte özet kabul oran› ile yay›na kabul aras›n ... Sivan M, Smith M, Bavikatte G, Bradley L. The academic value of rehabilitation medicine meetings. ...
Journal of Pediatric Orthopaedics, 2016
Traditional growing rods have a reported wound and implant complication rate as high as 58%. It i... more Traditional growing rods have a reported wound and implant complication rate as high as 58%. It is unclear whether the use of magnetically controlled growing rods (MCGR) will affect this rate. This study was performed to characterize surgical complications following MCGR in early onset scoliosis. A multicenter retrospective review of MCGR cases was performed. Inclusion criteria were: (1) diagnosis of early onset scoliosis of any etiology; (2) 10 years and younger at time of index surgery; (3) preoperative major curve size &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;30 degrees; (4) preoperative thoracic spine height &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;22 cm. Complications were categorized as wound related and instrumentation related. Complications were also classified as early (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;6 mo from index surgery) versus late (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;6 mo). Distraction technique and interval of distraction was surgeon preference without standardization across sites. Fifty-four MCGR patients met inclusion criteria. There were 30 primary and 24 conversion procedures. Mean age at initial surgery was 7.3 years (range, 2.4 to 11 y), and mean duration of follow-up 19.4 months. Twenty-one (38.8%) of 54 patients had at least 1 complication. Fifteen (27.8%) had at least 1 revision surgery. Six (11.1%) had broken rods (2 to 4.5 and 4 to 5.5 mm rods); two 5.5 mm rods failed early (4 mo) and 4 late (mean=14.5 mo). Six (11.1%) patients experienced 1 episode of lack or loss of lengthening, of which 4 patients subsequently lengthened. Seven patients (13.0%) had either proximal or distal fixation-related complication at average of 8.4 months. Two patients (3.7%) had infections requiring incision and drainage; 1 early (2 wk) with wound drainage and 1 late (8 mo). The late case required removal of one of the dual rods. This study shows that compared with traditional growing rods, MCGR has a lower infection rate (3.7% vs. 11.1%). MCGR does not appear to prevent common implant-related complications such as rod or foundation failure. The long-term implication remains to be determined. Level IV.
Acta Orthopaedica Et Traumatologica Turcica, Feb 1, 2004
During the past two decades, there has been a significant increase in sports participation by ped... more During the past two decades, there has been a significant increase in sports participation by pediatric athletes. Spinal injuries thus have become a great concern. The unique nature of the pediatric spine should be well-recognized and low back pain in a pediatric athlete should therefore be taken seriously and evaluated thoroughly. In this review article, sports-related lumbar spine problems will be covered including overuse injuries, spondylolysis, pars stress fractures, spondylolysthesis, and lumbar disc herniation. Early identification of these problems will eventually minimize these injuries.