DARPA – NIH Director's Blog (original) (raw)

Distinctive Brain ‘Subnetwork’ Tied to Feeling Blue

Posted on November 20th, 2018 by Dr. Francis Collins

Credit: :iStock/kieferpix

Experiencing a range of emotions is a normal part of human life, but much remains to be discovered about the neuroscience of mood. In a step toward unraveling some of those biological mysteries, researchers recently identified a distinctive pattern of brain activity associated with worsening mood, particularly among people who tend to be anxious.

In the new study, researchers studied 21 people who were hospitalized as part of preparation for epilepsy surgery, and took continuous recordings of the brain’s electrical activity for seven to 10 days. During that same period, the volunteers also kept track of their moods. In 13 of the participants, low mood turned out to be associated with stronger activity in a “subnetwork” that involved crosstalk between the brain’s amygdala, which mediates fear and other emotions, and the hippocampus, which aids in memory.

Posted In: News

Tags: amygdala, anxiety, anxiety disorders, artificial intelligence, brain, brain connectivity, BRAIN Initiative, brain networks, brain stimulation, DARPA, depression, epilepsy, hippocampus, iEEG, intracranial electroencephalography, memory, mood, mood disorder, neurology, seizures, SUBNETS, surgery

Welcoming the BRAIN Initiative

Posted on April 2nd, 2013 by Dr. Francis Collins

Introducing the President at the BRAIN Initiative event in the East Room of the White House
(Official White House Photo by Chuck Kennedy)

What an exciting day for science and innovation in the United States! I was thrilled to be present at the White House this morning, as President Barack Obama announced a pioneering project to explore the complex workings of the human brain: the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. And I’m proud to report that NIH-supported scientists will be among those at the forefront of this ambitious endeavor.

I’d like to take this opportunity to encourage each of you—whether you’re a researcher, health professional, patient, or young person interested in science—to embrace the BRAIN Initiative. Not only will this landmark effort continue our nation’s strong tradition of scientific innovation, it will advance NIH’s mission of turning scientific discoveries into better health for all.

For more details on the BRAIN Initiative, check out what DARPA chief Arati Prabhakar and I have to say on WhiteHouse.gov blog.