insulin sensitivity – NIH Director's Blog (original) (raw)
Obesity Research: Study Shows Significant Benefits of Modest Weight Loss
Posted on March 1st, 2016 by Dr. Francis Collins
For the one in three American adults who are obese, recommendations to lose substantial amounts of weight through a combination of diet and exercise can seem daunting and, at times, hopeless. But a new study should come as encouraging news for all those struggling to lose the extra pounds: even a modest goal of 5 percent weight loss delivers considerable health benefits.
In the NIH-funded study, people with obesity who lost just 5 percent of their body weight—about 12 pounds on average—showed improvements in several risk factors for type 2 diabetes and heart disease. They also showed metabolic improvements in many parts of the body, including the liver, pancreas, muscle, and fat tissue. While people who lost additional weight enjoyed further improvements in their health, the findings reported in the journal Cell Metabolism show that sometimes it really does pay to start small [1].
Tags: adipose tissue, diabetes, diet, fat, heart disease, insulin resistance, insulin sensitivity, metabolism, moderate weight loss, obesity, overweight, pancreatic beta cells, progressive weight loss, type 2 diabetes, weight, weight loss