Talal Aburjai | The University Of Jordan (original) (raw)

Papers by Talal Aburjai

American Journal of Pharmaceutical Education, 2019

European Journal of Medicinal Chemistry, 1992

The study was carried out to identify the compound responsible for hypolipidemic and hypoglycemic... more The study was carried out to identify the compound responsible for hypolipidemic and hypoglycemic effects of Cajanus cajan (redgram). The methanol extract of redgram seeds were fractionated into petroleum ether, chloroform, and methanol. The methanol fraction significantly decreased fasting blood glucose, and lipid profiles (p<0.001) on streptozotocin-induced mice compared to control. The methanol fraction was then subjected to chromatographic analysis and a compound (CCA1) has been isolated. The structure of the compound is considered to be substituted cyclopentene with glucose by analysis its 1 H and 13 C-NMR data. Biological studies of the isolated compound possessed prominent hypolipidemic activity. Although a number of hypoglycemic compounds are reported, yet not any hypolipidemic compound from redgram. The compound CCA1 seems to be the first report on hypolipidemic activity from methanol extract of redgram.

Tropical Journal of Pharmaceutical Research, 2022

Purpose: To develop a reversed phase high performance liquid chromatography (HPLC) method for the... more Purpose: To develop a reversed phase high performance liquid chromatography (HPLC) method for the determination of dehydroepiandrosterone (DHEA) in dietary supplements. Methods: A reversed-phase high performance liquid chromatography (HPLC) method was developed for the determination of DHEA in dietary supplements. An isocratic system consisting of methanol and water (70:30 v/v) was run at a flow rate of 1 mL/min on a C18 HPLC column to achieve the separation. The method was validated with regard to linearity, intra-day and inter-day precision, and limits of both detection and quantification. Results: The method achieved a retention time of 10.8 min, a resolution of 4.12, a detection limit (LOD) of 50 ng/μL, a quantification limit (LOQ) of 166.7 ng/μL and a label claim of 108.6 % with a relative standard deviation (RSD) of 0.38 % over a range of 0.0625 – 0.50 mg/mL with a correlation coefficient of 0.9997. Conclusion: The method is simple, cost effective, time-saving and reliable for...

Journal of Herbs, Spices & Medicinal Plants, 2010

Plant samples from wild populations of Hypericum triquetrifolium were collected from different se... more Plant samples from wild populations of Hypericum triquetrifolium were collected from different sections of Jordan and introduced for cultivation under nitrogen fertilization treatments for 2 years. The cultivated populations varied widely in plant height, width, dry weight, hypericin content, number of days to flowering and fruit capsule formation, and response to nitrogen fertilization. In general, hypericin content of the plant

Journal of Decision Systems, 1995

Acutalización de la integración del comité editorial de esta casa. Especialistas que tienen a su ... more Acutalización de la integración del comité editorial de esta casa. Especialistas que tienen a su cargo la selección y evaluación de materiales así como la dirección de las diferentes colecciones que componen nuestro catálogo.

International Journal of Research in Pharmaceutical Sciences, 2020

Helicobacter pylori, a gram-negative bacterium, known factor for chronic active gastritis, stomac... more Helicobacter pylori, a gram-negative bacterium, known factor for chronic active gastritis, stomach and peptic ulceration, which may progress to gastric cancer. It is also associated with other non-gastric diseases such as stroke, diabetes mellitus and alzheimer’s disease. Although conventional treatment achieved a great advancements in controlling H.pylori infection nowadays it is not effective thus it’s intended to find some other alternative sources that may be used alone or in combination with antibiotics to eradicate the infection. Recently published literature of natural sources such as plant -derived bioactive compounds and probiotics are studied for their reduced side effects and for being safe and inexpensive. However, the mechanism of action by which these herbs and probiotics exert their medicinal properties in H.pylori treatment is still not fully clear. In this review, we highlight the potential antibacterial mechanisms of some traditionally used bioactive compounds and ...

Journal of Diseases and Medicinal Plants, 2019

Journal of Ethnobiology and Ethnomedicine, 2013

Background This study aims to analyze and record orally transmitted knowledge of medicinal plants... more Background This study aims to analyze and record orally transmitted knowledge of medicinal plants from the indigenous people living in Hallasan National Park of Korea. Methods Data was collected through the participatory rural appraisal method involving interviews, informal meetings, open and group discussions, and overt observations with semi-structured questionnaires. Results In this study, a total of 68 families, 141 genera, and 171 species of plants that showed 777 ways of usage were recorded. Looking into the distribution of the families, 14 species of Asteraceae occupied 11.1% of the total followed by 13 species of Rosaceae, 10 species of Rutaceae, and nine species of Apiaceae which occupied 5.0%, 7.1% and 3.0% of the whole, respectively. 32 kinds of plant-parts were used for 47 various medicinal purposes. Values for the informant consensus factor regarding the ailment categories were for birth related disorders (0.92), followed by respiratory system disorders (0.90), skin dis...

The Natural Products Journal, Jun 16, 2021

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The nematicidal activity of methanolic extracts (20 µg ml-1) from twenty Jordanian plant species ... more The nematicidal activity of methanolic extracts (20 µg ml-1) from twenty Jordanian plant species against two species of root-knot nematodes in vitro was evaluated. Whole-plant extract of Hypericum androsaemum showed the highest activity (11% mortality) against Meloidogyne javanica after 24 h of incubation. However, leaf extract of Origanum syriacum also increased M. javanica mortality markedly a day later, reaching 59 and 82% after 48 and 72 h of exposure respectively. Against M. incognita the response of leaf extracts was somewhat different, with leaf extract of Artemisia herba alba the most effective causing 22, 51, 54% mortality after 24, 48 and 72 h of exposure respectively. With a tenfold concentration (200 µg ml-1) of those plant extracts thought to contain volatile oils, the secondstage juveniles (J2) mortality of both nematodes increased after 24 and 72 h of incubation. Nematicidal tests of some volatile oils that are active ingredients of the plants tested revealed that geraniol, thymol, and camphor were the most effective against M. javanica J2s, with 91, 60, 56% mortality respectively after 72 h of exposure. Cineole, menthol, and pinene were not effective against this nematode. Against M. incognita J2s, the most effective oil components were carvacol, thymol, and geraniol, with mortalities of 100, 90, and 74% respectively after 72 h of exposure. Cineole was the least effective against M. incognita.

Jordan Journal of Pharmaceutical Sciences, Jun 2, 2011

International Journal of Pharmacology, 2012

In this study, the medicinal plants used in the treatment of diabetes mellitus were inventoried. ... more In this study, the medicinal plants used in the treatment of diabetes mellitus were inventoried. The ethnopharmacological information was obtained from 470 patients suffering from diabetes mellitus in different areas in the North Western and South Western Algeria; 266 of them were of type 2 diabetes. The results indicated that only 28.30% of patients interviewed used medicinal plants as treatment alone or in association with the conventional treatment of diabetes. 60 medicinal plants belonging to 32 families were cited, of which the most cited were: Trigonella foenum-graecum (56 citations), Rosmarinus officinalis (27 citations), Citrullus colocynthis (22 citations), Tetraclinis articulata (21 citations), Artemesia herba alba (20 citations), Origanum compactum (16 citations) and Punica granatum (16 citations). The plants families' which contained the most commonly used species and their antidiabetic effects were: Asteraceae (8 species), Lamiaceae (8 species) and Apiaceae (4 species). Among these medicinal plants, five plants were known to be toxic: Nerium oleander, C. colocynthis, Zygophyllum album, Nigella sativa and Peganum harmala.

UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi

The aim of the present study was to investigate the lipid pattern in Jordanian children with Beta... more The aim of the present study was to investigate the lipid pattern in Jordanian children with Beta-thalassemia major (ß-TM). Twenty six transfusion dependent ß-TM patients, 14 males and 12 females, (mean age 9 ± 5 years) that under-go periodical blood transfusion and desferioxame as a chelating agent, were studied. Twenty controls of matched age and gender were also included in the study. ß-thalassemia major patients showed significantly lower total cholesterol, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol when compared with control. Serum triglycerides levels of TM patients were found to be significantly higher than levels in control subjects. Our results revealed that lipid profile changed in patients with major ß-TM. Many factors such as iron overload, liver injury, hor-monal disturbances and aging might cause these changes. ÖZET ß-Talassemi Majör Hastası Ürdünlü Çocuklarda Lipid Profili Bu çalışmanın amacı, ß-talassemi (ß-TM) majör hastası olan Ürd...

Journal of essential oil-bearing plants JEOP

Background: Gastritis and peptic ulcer are considered major health problems worldwide. It has bee... more Background: Gastritis and peptic ulcer are considered major health problems worldwide. It has been reported that more than 80% of chronic active gastritis are due to the pathogenic bacterium Helicobacter pylori where persistent infection remains for decades. Successful treatment of H. pylori routinely requires the use of multiple agents with different mechanisms including compounds inhibiting acid secretion in conjunction with Antibiotics. However, recent data showed the emergence of resistant clinical strains particularly against metronidazole and clarithromycin. The aim of this study is to test the antimicrobial activity of selected local medicinal herbs and their oils against H. pylori and to determine if the tested plants could have inhibitory activity against H. pylori urease. Materials and Methods: Oils of Cinnamomum zeylanicum, Origanum syriacum, Foeniculum vulgare, Lavandula angustifolia, Coriandrum sativum, Pimpinella anisum, Rosmarinus officinalis, Carum carvi, Syzygium ar...

American Journal of Analytical Chemistry, 2011