Targeting transforming growth factor (TGF)‐βRI inhibits... : Hepatology (original) (raw)

Hepatobiliary Malignancies

Targeting transforming growth factor (TGF)‐βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma†

Fransvea, Emilia1,‡; Mazzocca, Antonio1,2,‡; Antonaci, Salvatore1; Giannelli, Gianluigi*,1,§

1Department of Internal Medicine, Immunology and Infectious Diseases, Section of Internal Medicine; University of Bari Medical School, Bari, Italy

2Department of Pathology, Vanderbilt University Medical Center, Nashville, TN

Dipartimento di Clinica Medica, Immunologia e Malattie Infettive, Sezione di Medicina Interna, Policlinico, piazza G. Cesare 11, 70124 Bari, Italy===

Received August 29, 2008

Accepted October 28, 2008